Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Dinesh C Joshi"'
Autor:
Dinesh C Joshi, Joanna C Bakowska
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19290 (2011)
Hereditary spastic paraplegias (HSPs) are a group of neurological disorders characterized clinically by spasticity of lower limbs and pathologically by degeneration of the corticospinal tract. Troyer syndrome is an autosomal recessive HSP caused by a
Externí odkaz:
https://doaj.org/article/f63c3e40ec1a48d8adda5db12d3dccb7
Autor:
Uzma Saeed, Lalitha Durgadoss, R Khader Valli, Dinesh C Joshi, Preeti G Joshi, Vijayalakshmi Ravindranath
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2459 (2008)
Mitochondrial dysfunction including that caused by oxidative stress has been implicated in the pathogenesis of neurodegenerative diseases. Glutaredoxin 1 (Grx1), a cytosolic thiol disulfide oxido-reductase, reduces glutathionylated proteins to protei
Externí odkaz:
https://doaj.org/article/64a2dc707bf04962ac03652fc750ebc6
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e21594- (2023)
Due to increased awareness regarding the health-promoting profile of millets, inclination towards their consumption has increased considerably. In the Himalayan region of India, cultivars of the two species of barnyard millet, namely Indian (Echinoch
Externí odkaz:
https://doaj.org/article/7e0460c1a91b42b8a5447cae7dbfcf01
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/c6e2a99f853041ad85c9478213b9f0f0
Autor:
Mario Sechi, Rahul K. Lall, Saheed O Afolabi, Anant Singh, Dinesh C. Joshi, Shing-Yan Chiu, Hasan Mukhtar, Deeba N. Syed
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract The anti-proliferative activity of dietary flavonoid fisetin has been validated in various cancer models. Establishing its precise mechanism of action has proved somewhat challenging given the multiplicity of its targets. We demonstrated tha
Externí odkaz:
https://doaj.org/article/5e2df20b2938453aa0b4f7b03494c319
Autor:
Dinesh C. Joshi, Chuan-Li Zhang, Deepali Mathur, Alex Li, Gaurav Kaushik, Zu-Hang Sheng, Shing-Yan Chiu
Publikováno v:
J Neurosci
The mitochondrial anchor syntaphilin (SNPH) is a key mitochondrial protein normally expressed in axons to maintain neuronal health by positioning mitochondria along axons for metabolic needs. However, in 2019 we discovered a novel form of excitotoxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa5eeaebdbecf65a609d74513fa41eb
https://europepmc.org/articles/PMC9512578/
https://europepmc.org/articles/PMC9512578/
Autor:
Dinesh C. Joshi, Krisztian Kovacs, Collin Laaker, Thanthrige Thiunuwan Priyathilaka, Shing Yan Chiu, TaeHee Kim, Peter Cismaru, Julie A. Kijak, Lee Kissel, Raghu Vemuganti, Matyas Sandor, Martin Hsu, Anders Lindstedt, Zsuzsanna Fabry, Aditya Rayasam
Background: Ischemic stroke is a leading cause of mortality worldwide, largely due to the inflammatory response to brain ischemia during post-stroke reperfusion. Despite ongoing intensive research, there have not been any clinically approved drugs ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::709cb24ba18707a6d07bb2b2b47ab201
https://doi.org/10.21203/rs.3.rs-1032310/v1
https://doi.org/10.21203/rs.3.rs-1032310/v1
Publikováno v:
Biodiversity and Conservation
Selective production of input intensive crops in the present scenario have resulted in productivity stagnation or even decline due to excessive usage of chemicals, affecting the farmers economically. Sustainable agriculture is the way to increase agr
Autor:
Chuan-Li Zhang, Dawiyat Massoudi, Dinesh C. Joshi, Alison M. Muir, Shing Yan Chiu, Guorui Huang, Daniel S. Greenspan
Publikováno v:
Cell Reports, Vol 20, Iss 4, Pp 923-934 (2017)
Regulated inter-mitochondrial fusion/fission is essential for maintaining optimal mitochondrial respiration and control of apoptosis and autophagy. In mammals, mitochondrial fusion is controlled by outer membrane GTPases MFN1 and MFN2 and by inner me
Autor:
Hasan Mukhtar, Rahul K. Lall, Dinesh C. Joshi, Anant Singh, Mario Sechi, Saheed O. Afolabi, Shing Yan Chiu, Deeba N. Syed
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports
Scientific Reports
The anti-proliferative activity of dietary flavonoid fisetin has been validated in various cancer models. Establishing its precise mechanism of action has proved somewhat challenging given the multiplicity of its targets. We demonstrated that YB-1 pr