Zobrazeno 1 - 10
of 244
pro vyhledávání: '"Dineo Khabele"'
Autor:
David Standing, Prasad Dandawate, Sumedha Gunewardena, Obdulia Covarrubias-Zambrano, Katherine F. Roby, Dineo Khabele, Andrea Jewell, Ossama Tawfik, Stefan H. Bossmann, Andrew K. Godwin, Scott J. Weir, Roy A. Jensen, Shrikant Anant
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-16 (2024)
Abstract Advanced epithelial ovarian cancer (EOC) survival rates are dishearteningly low, with ~25% surviving beyond 5 years. Evidence suggests that cancer stem cells contribute to acquired chemoresistance and tumor recurrence. Here, we show that IRA
Externí odkaz:
https://doaj.org/article/a34cd1f4ae354f69b2bfaed9395015fa
Autor:
Mary M. Mullen, Whitney R. Grither, Hannah Millimet, David G. Mutch, Andrea R. Hagemann, Carolyn K. McCourt, Matthew A. Powell, Premal H.Thaker, Dineo Khabele, Lindsay M. Kuroki
Publikováno v:
Gynecologic Oncology Reports, Vol 55, Iss , Pp 101476- (2024)
No prospective data have been described to inform guidelines on antibiotic prophylaxis for partial vulvectomies. Thus, we conducted a single-center, pilot, double-blind randomized controlled trial to assess the effectiveness of prophylactic antibioti
Externí odkaz:
https://doaj.org/article/6f5b609b75aa4ab9991e5977d56f02d0
Autor:
Emilee N. Kotnik, Mary M. Mullen, Nicholas C. Spies, Tiandao Li, Matthew Inkman, Jin Zhang, Fernanda Martins-Rodrigues, Ian S. Hagemann, Carolyn K. McCourt, Premal H. Thaker, Andrea R. Hagemann, Matthew A. Powell, David G. Mutch, Dineo Khabele, Gregory D. Longmore, Elaine R. Mardis, Christopher A. Maher, Christopher A. Miller, Katherine C. Fuh
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract High-grade serous ovarian cancer (HGSC) is the most lethal histotype of ovarian cancer and the majority of cases present with metastasis and late-stage disease. Over the last few decades, the overall survival for patients has not significant
Externí odkaz:
https://doaj.org/article/12406fa62eb94e7ab6b8f750b0d58be6
Autor:
Evan B. Glass, Alyssa A. Hoover, Kennady K. Bullock, Matthew Z. Madden, Bradley I. Reinfeld, Whitney Harris, Dominique Parker, Demetra H. Hufnagel, Marta A. Crispens, Dineo Khabele, W. Kimryn Rathmell, Jeffrey C. Rathmell, Andrew J. Wilson, Todd D. Giorgio, Fiona E. Yull
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-19 (2022)
Abstract Background Current cancer immunotherapies have made tremendous impacts but generally lack high response rates, especially in ovarian cancer. New therapies are needed to provide increased benefits. One understudied approach is to target the l
Externí odkaz:
https://doaj.org/article/695878c019a54c44a19092e66e5e5079
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 24, Iss 2, Pp 63-75 (2022)
Histone deacetylase inhibitors (HDACi) sensitize homologous recombination (HR)-proficient human ovarian cancer cells to PARP inhibitors (PARPi). To investigate mechanisms of anti-tumor effects of combined HDACi/PARPi treatment we performed transcript
Externí odkaz:
https://doaj.org/article/8bc38eee187b4be7af6ce79aa0344d9a
Autor:
Abigail S. Zamorano, Angela L. Mazul, Christine Marx, Mary M. Mullen, Molly Greenwade, L. Stewart Massad, Carolyn K. McCourt, Andrea R. Hagemann, Premal H. Thaker, Katherine C. Fuh, Matthew A. Powell, David G. Mutch, Dineo Khabele, Lindsay M. Kuroki
Publikováno v:
Gynecologic Oncology Reports, Vol 44, Iss , Pp 101075- (2022)
Objective: Given the importance of understanding neighborhood context and geographic access to care on individual health outcomes, we sought to investigate the association of community primary care (PC) access on postoperative outcomes and survival i
Externí odkaz:
https://doaj.org/article/b7febea31b1c413c97af000167911e6c
Autor:
Shaina F. Bruce, Bridget Huysman, Jinai Bharucha, L. Stewart Massad, Mary M. Mullen, Andrea R. Hagemann, Katherine C. Fuh, Carolyn K. McCourt, Premal H. Thaker, Dineo Khabele, Matthew A. Powell, David G. Mutch, Lindsay M. Kuroki
Publikováno v:
Gynecologic Oncology Reports, Vol 39, Iss , Pp 100928- (2022)
Objective: To evaluate the impact of the COVID-19 pandemic on referral to and delivery of gynecologic oncology care at a National Cancer Institute-designated Comprehensive Cancer Center. Methods: We conducted a retrospective cohort study of patients
Externí odkaz:
https://doaj.org/article/cd58a6485c204bb4bb721ee713cba000
Autor:
Alyssa A. Hoover, Demetra H. Hufnagel, Whitney Harris, Kennady Bullock, Evan B. Glass, Esther Liu, Whitney Barham, Marta A. Crispens, Dineo Khabele, Todd D. Giorgio, Andrew J. Wilson, Fiona E. Yull
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-16 (2020)
Abstract Background New treatment options for ovarian cancer are urgently required. Tumor-associated macrophages (TAMs) are an attractive target for therapy; repolarizing TAMs from M2 (pro-tumor) to M1 (anti-tumor) phenotypes represents an important
Externí odkaz:
https://doaj.org/article/1721307f4b964b83b11c876f207a8f61
Autor:
Demetra H. Hufnagel, Andrew J. Wilson, Jamie Saxon, Timothy S. Blackwell, Jaclyn Watkins, Dineo Khabele, Marta A. Crispens, Fiona E. Yull, Alicia Beeghly-Fadiel
Publikováno v:
Biomarker Research, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract Background The canonical and non-canonical nuclear factor-kappaB (NF-κB) signaling pathways have key roles in cancer, but studies have previously evaluated only the association of canonical transcription factors and ovarian cancer survival.
Externí odkaz:
https://doaj.org/article/64b228fc34df4340b790ce58498187c7
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 15, Iss 7-8, Pp 1851-1855 (2019)
Objective: The primary aim of this study is to assess and characterize correlates of human papillomavirus (HPV) vaccine series completion among young adult women evaluated by gynecological (GYN) providers at a single institution and to measure change
Externí odkaz:
https://doaj.org/article/c69e3db4306748dd8094b4b198fbe567