Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Dinendra L Abeyawardhane"'
Autor:
Rodrigo Lázaro‐Gorines, Patricia Pérez, Ignacio Heras‐Murillo, Irene Adán‐Barrientos, Guillermo Albericio, David Astorgano, Sara Flores, Joanna Luczkowiak, Nuria Labiod, Seandean L. Harwood, Alejandro Segura‐Tudela, Laura Rubio‐Pérez, Yudhi Nugraha, Xiaoran Shang, Yuxing Li, Carlos Alfonso, Kaylin A. Adipietro, Dinendra L. Abeyawardhane, Rocío Navarro, Marta Compte, Wenbo Yu, Alexander D. MacKerell Jr, Laura Sanz, David J. Weber, Francisco J. Blanco, Mariano Esteban, Edwin Pozharski, Raquel Godoy‐Ruiz, Inés G. Muñoz, Rafael Delgado, David Sancho, Juan García‐Arriaza, Luis Álvarez‐Vallina
Publikováno v:
Advanced Science, Vol 10, Iss 34, Pp n/a-n/a (2023)
Abstract Administration of neutralizing antibodies (nAbs) has proved to be effective by providing immediate protection against SARS‐CoV‐2. However, dual strategies combining virus neutralization and immune response stimulation to enhance specific
Externí odkaz:
https://doaj.org/article/83ee823ecfc342e88a1c1efafa321622
Autor:
Alyson M. Curry, Ricardo D. Fernàndez, Talita D. Pagani, Dinendra L. Abeyawardhane, Morgan L. Trahan, Heather R. Lucas
Publikováno v:
Life, Vol 10, Iss 8, p 124 (2020)
Parkinson’s disease (PD) is the second most common neurological disease and belongs to a group of neurodegenerative disorders called synucleinopathies in which pathological aggregates of N-terminally acetylated α-synuclein (NAcα-Syn) accumulate i
Externí odkaz:
https://doaj.org/article/006ac66b514b49c7a45f769094777a04
Autor:
Joel W Roberts, Heather R. Lucas, Dinendra L Abeyawardhane, Alyson M. Curry, Ashley K. Forney
Publikováno v:
J Biol Inorg Chem
Metal dyshomeostasis has long been linked to Parkinson’s disease (PD), and the amyloidogenic protein α-synuclein (αS) is universally recognized as a key player in PD pathology. Structural consequences upon coordination of copper and iron to αS h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060961e8184a17b469211ab371a0fe54
https://doi.org/10.1007/s00775-019-01738-2
https://doi.org/10.1007/s00775-019-01738-2
Autor:
Kaylin A. Adipietro, Kristen M. Varney, Dinendra L Abeyawardhane, David J. Weber, Edwin Pozharski, Raquel Godoy-Ruiz
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f50c0542516439ff429f88a357263deb
https://doi.org/10.1096/fasebj.2021.35.s1.04607
https://doi.org/10.1096/fasebj.2021.35.s1.04607
Autor:
David J. Weber, Kaylin A. Adipietro, Raquel Godoy-Ruiz, Richard R. Rustandi, Dinendra L Abeyawardhane, E. Pozharski, Kristen M. Varney
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2926, p 2926 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Novel therapeutics are needed to treat pathologies associated with the Clostridioides difficile binary toxin (CDT), particularly when C. difficile infection (CDI) occurs in the elderly or in hospitalized patients having illnesses, in addition to CDI,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae709f02a64e5e700d76dcc5a804ffb
https://www.mdpi.com/1422-0067/22/6/2926
https://www.mdpi.com/1422-0067/22/6/2926
Autor:
Dinendra L Abeyawardhane, Morgan L Trahan, Heather R. Lucas, Ricardo D. Fernández, Talita D Pagani, Alyson M. Curry
Publikováno v:
Life, Vol 10, Iss 124, p 124 (2020)
Life
Volume 10
Issue 8
Life
Volume 10
Issue 8
Parkinson&rsquo
s disease (PD) is the second most common neurological disease and belongs to a group of neurodegenerative disorders called synucleinopathies in which pathological aggregates of N-terminally acetylated &alpha
synuclein (NAc&a
s disease (PD) is the second most common neurological disease and belongs to a group of neurodegenerative disorders called synucleinopathies in which pathological aggregates of N-terminally acetylated &alpha
synuclein (NAc&a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::514243a9d844cdd6fd74f636e129e810
https://www.mdpi.com/2075-1729/10/8/124
https://www.mdpi.com/2075-1729/10/8/124
Autor:
Heather R. Lucas, Madeleine K Crozier, Dinendra L Abeyawardhane, Ricardo D. Fernández, Denver R. Heitger, Julia C Wolver
Publikováno v:
Journal of the American Chemical Society. 140:17086-17094
Aggregation of the neuronal protein α-synuclein (αS) is a critical factor in the pathogenesis of Parkinson’s disease. Analytical methods to detect post-translational modifications of αS are under development, yet the mechanistic underpinnings of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d137f3a953a1799ec6b394f9a25301cf
https://doi.org/10.1021/jacs.8b08947
https://doi.org/10.1021/jacs.8b08947
Autor:
Ashley K. Forney, Dinendra L Abeyawardhane, Ricardo D. Fernández, Heather R. Lucas, Denver R. Heitger
Publikováno v:
ACS Chemical Neuroscience. 10:1402-1410
The structurally dynamic amyloidogenic protein α-synuclein (αS) is universally recognized as a key player in Parkinson’s disease (PD). Copper, which acts as a neuronal signaling agent, is also an effector of αS structure, aggregation, and locali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89a969b63b8e0d54b5997411949b6e7e
https://doi.org/10.1021/acschemneuro.8b00448
https://doi.org/10.1021/acschemneuro.8b00448
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
The etiology of Parkinson’s disease (PD) is linked with cellular inclusions in the substantia nigra pars compacta region of the brain that are enriched in the misfolded presynaptic protein α-synuclein (αS) and death of the dopaminergic neurons. B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3163b99c2a0c5a120841f94d81b76963
http://europepmc.org/articles/PMC6803728
http://europepmc.org/articles/PMC6803728
Autor:
Dinendra L, Abeyawardhane, Denver R, Heitger, Ricardo D, Fernández, Ashley K, Forney, Heather R, Lucas
Publikováno v:
ACS chemical neuroscience. 10(3)
The structurally dynamic amyloidogenic protein α-synuclein (αS) is universally recognized as a key player in Parkinson's disease (PD). Copper, which acts as a neuronal signaling agent, is also an effector of αS structure, aggregation, and localiza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ff33e3c5c7d8f9d45ec6c0bf38ee3f9
https://pubmed.ncbi.nlm.nih.gov/30384594
https://pubmed.ncbi.nlm.nih.gov/30384594