Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Dinah, Misner"'
Autor:
Xuan G Luong, Sarah K Stevens, Andreas Jekle, Tse-I Lin, Kusum Gupta, Dinah Misner, Sushmita Chanda, Sucheta Mukherjee, Caroline Williams, Antitsa Stoycheva, Lawrence M Blatt, Leonid N Beigelman, Julian A Symons, Pierre Raboisson, David McGowan, Koen Vandyck, Jerome Deval
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0240338 (2020)
Thyroid hormones are important modulators of metabolic activity in mammals and alter cholesterol and fatty acid levels through activation of the nuclear thyroid hormone receptor (THR). Currently, there are several THRβ agonists in clinical trials fo
Externí odkaz:
https://doaj.org/article/9888716071a5408e90bb5d9370ea3a38
Autor:
WeiYu Lin, Daqi Xu, Cary D. Austin, Patrick Caplazi, Kate Senger, Yonglian Sun, Surinder Jeet, Judy Young, Donnie Delarosa, Eric Suto, Zhiyu Huang, Juan Zhang, Donghong Yan, Cesar Corzo, Kai Barck, Sharmila Rajan, Carrie Looney, Vineela Gandham, Justin Lesch, Wei-Ching Liang, Elaine Mai, Hai Ngu, Navneet Ratti, Yongmei Chen, Dinah Misner, Tori Lin, Dimitry Danilenko, Paula Katavolos, Estelle Doudemont, Hirdesh Uppal, Jeffrey Eastham, Judy Mak, Patricia E. de Almeida, Katherine Bao, Azadeh Hadadianpour, Mary Keir, Richard A. D. Carano, Lauri Diehl, Min Xu, Yan Wu, Robby M. Weimer, Jason DeVoss, Wyne P. Lee, Mercedesz Balazs, Kevin Walsh, Kathila R. Alatsis, Flavius Martin, Ali A. Zarrin
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Colony-stimulating factor 1 (CSF1) and interleukin 34 (IL34) signal via the CSF1 receptor to regulate macrophage differentiation. Studies in IL34- or CSF1-deficient mice have revealed that IL34 function is limited to the central nervous system and sk
Externí odkaz:
https://doaj.org/article/f5bbd900f7f94b86b15fbd853c8ad352
Autor:
Sultan Chowdhury, Christoph Martin Dehnhardt, Tao Sheng, Clint Young, Rainbow Kwan, Michael Scott Wilson, Jun Chen, Matthew Waldbrook, Dinah Misner, C. Lee Robinette, Rebecca M. Reese, Elaine Chang, Henry Verschoof, Tanja S. Zabka, Girish Bankar, Philippe Bergeron, Luis Sojo, Karen Nelkenbrecher, Daniel P. Sutherlin, Amy Kim, Ivan William Hemeon, Andrea Lindgren, Jae H. Chang, Alla Yurevna Zenova, Shaoyi Sun, Jonathan Maher, Shannon D. Shields, Jun Li, Daniel F. Ortwine, David H. Hackos, Zhiwei Xie, Thilo Focken, Charles J. Cohen, Richard T. Dean, Shannon Decker, Janette Mezeyova, Kuldip Khakh, Antonio G. DiPasquale, Chien-An Chen, Andrew D. White, Brian Safina, Jodie Pang, Qi Jia, Sophia Lin, Jean-Christophe Andrez, J. P. Johnson, Steven J. McKerrall
Publikováno v:
Journal of Medicinal Chemistry. 64:2953-2966
Nav1.7 is an extensively investigated target for pain with a strong genetic link in humans, yet in spite of this effort, it remains challenging to identify efficacious, selective, and safe inhibitors. Here, we disclose the discovery and preclinical p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a8a9431d81bf8ca2eed0fbbfbb36905
https://doi.org/10.1021/acs.jmedchem.1c00049
https://doi.org/10.1021/acs.jmedchem.1c00049
Autor:
Joseph W. Lubach, Jennifer Vogt, Wendy B. Young, Charles Eigenbrot, Arna Katewa, James J. Crawford, Dinah Misner, Harvey Wong, Hans E. Purkey, Wendy Lee, Adam R. Johnson, Karin Reif, Jacob Z. Chen, Satoko Kakiuchi-Kiyota, Lichuan Liu, Julia Heidmann, Christine Yu, James R. Kiefer, Kelly J. Delatorre
Publikováno v:
ACS Med Chem Lett
[Image: see text] Bruton’s tyrosine kinase (Btk) is thought to play a pathogenic role in chronic immune diseases such as rheumatoid arthritis and lupus. While covalent, irreversible Btk inhibitors are approved for treatment of hematologic malignanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::741c155f1116115d9a133dcec622d3c8
https://doi.org/10.1021/acsmedchemlett.0c00249
https://doi.org/10.1021/acsmedchemlett.0c00249
Autor:
Leonid Beigelman, Jerome Deval, Lawrence M. Blatt, Dorothée Bardiot, Laura Vangeel, Sandro Boland, Johan Neyts, Cheng Liu, Steven Dejonghe, Dinah Misner, Andreas Jekle, Pierre Raboisson, Sushmita Mukherjee Chanda, Vladimir Serebryany, Caroline S. Foo, Koen Vandyck, Arnaud Marchand, Suping Ren, Julian A. Symons, Patrick Chaltin, Kusum Gupta, Antitsa Dimitrova Stoycheva, Dirk Jochmans, Rana Abdelnabi
Publikováno v:
Biochemical and Biophysical Research Communications
There is an urgent need for antivirals targeting the SARS-CoV-2 virus to fight the current COVID-19 pandemic. The SARS-CoV-2 main protease (3CLpro) represents a promising target for antiviral therapy. The lack of selectivity for some of the reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f364b0af0bca75044f48bf96844cbe8
https://lirias.kuleuven.be/handle/123456789/673810
https://lirias.kuleuven.be/handle/123456789/673810
Autor:
Brian S, Safina, Steven J, McKerrall, Shaoyi, Sun, Chien-An, Chen, Sultan, Chowdhury, Qi, Jia, Jun, Li, Alla Y, Zenova, Jean-Christophe, Andrez, Girish, Bankar, Philippe, Bergeron, Jae H, Chang, Elaine, Chang, Jun, Chen, Richard, Dean, Shannon M, Decker, Antonio, DiPasquale, Thilo, Focken, Ivan, Hemeon, Kuldip, Khakh, Amy, Kim, Rainbow, Kwan, Andrea, Lindgren, Sophia, Lin, Jonathan, Maher, Janette, Mezeyova, Dinah, Misner, Karen, Nelkenbrecher, Jodie, Pang, Rebecca, Reese, Shannon D, Shields, Luis, Sojo, Tao, Sheng, Henry, Verschoof, Matthew, Waldbrook, Michael S, Wilson, Zhiwei, Xie, Clint, Young, Tanja S, Zabka, David H, Hackos, Daniel F, Ortwine, Andrew D, White, J P, Johnson, C Lee, Robinette, Christoph M, Dehnhardt, Charles J, Cohen, Daniel P, Sutherlin
Publikováno v:
Journal of medicinal chemistry. 64(6)
Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d744b2a5894fa87236be1caf92c75b8b
https://pubmed.ncbi.nlm.nih.gov/33682420
https://pubmed.ncbi.nlm.nih.gov/33682420
Autor:
Andreas Jekle, Julian A. Symons, Sushmita Mukherjee Chanda, Vladimir Serebryany, Leonid Beigelman, Cheng Liu, Rana Abdelnabi, Suping Ren, Steven Dejonghe, Sandro Boland, Johan Neyts, Dorothée Bardiot, Dinah Misner, Antitsa Dimitrova Stoycheva, Patrick Chaltin, Jerome Deval, Pierre Raboisson, Kusum Gupta, Koen Vandyck, Dirk Jochmans, Caroline S. Foo, Arnaud Marchand, Lawrence M. Blatt, Laura Vangeel
There is an urgent need for antivirals targeting the SARS-CoV-2 virus to fight the current COVID-19 pandemic. The SARS-CoV-2 main protease (3CLpro) represents a promising target for antiviral therapy. The lack of selectivity for some of the reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b7502a8f400fdb028d390f18fc0e96d
https://doi.org/10.1101/2021.02.14.431129
https://doi.org/10.1101/2021.02.14.431129
Autor:
Qingling Zhang, Sandrine Vendeville, Vladimir Serebryany, Michael Welch, Jyanwei Liu, Caroline Williams, Yannick Debing, Andreas Jekle, Sarah Stevens, Jerome Deval, Tse-I Lin, Dinah Misner, Sushmita Chanda, Raymond F Schinazi, Pierre Raboisson, Julian Symons, Lawrence Blatt, Leonid Beigelman, David Smith
Publikováno v:
Journal of Hepatology. 73:S880-S881
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c713245d075a3f7f79675b8f04f1ab0e
https://doi.org/10.1016/s0168-8278(20)32200-5
https://doi.org/10.1016/s0168-8278(20)32200-5
Autor:
Jin Hong, Rajendra Pandey, Vivek Rajwanshi, Dinah Misner, Hua Tan, John Cortez, Yuchun Nie, Suping Ren, Dana Cho, Laxman Eltepu, Tilani De Costa, Priya Mishra, Kang Hyunsoon, Aneerban Bhattacharya, Sushmita Chanda, David Smith, Julian Symons, Lawrence Blatt, Leonid Beigelman
Publikováno v:
Journal of Hepatology. 73:S869-S870
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a32afbb7ebcd82d03ede2f573f25859
https://doi.org/10.1016/s0168-8278(20)32181-4
https://doi.org/10.1016/s0168-8278(20)32181-4
Autor:
Sharmila Rajan, Eric Suto, Judy Young, Kevin Walsh, Wyne P. Lee, Yongmei Chen, Elaine Mai, Dinah Misner, Kate Senger, Dimitry M. Danilenko, Navneet Ratti, Ali A. Zarrin, Mary E. Keir, Patrícia de Almeida, Justin Lesch, Judy Mak, Kai H. Barck, Cary D. Austin, Cesar A. Corzo, Zhiyu Huang, Flavius Martin, Carrie Looney, Hirdesh Uppal, Hai Ngu, Yonglian Sun, Vineela D. Gandham, Wei-Ching Liang, Lauri Diehl, Surinder Jeet, Estelle Doudemont, Tori Lin, Jason DeVoss, Jeffrey Eastham, Wei Yu Lin, Azadeh Hadadianpour, Kathila R. Alatsis, Donnie Delarosa, Paula Katavolos, Juan Zhang, Katherine Bao, Richard A.D. Carano, Patrick Caplazi, Min Xu, Yan Wu, Robby M. Weimer, Mercedesz Balazs, Donghong Yan, Daqi Xu
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
Colony-stimulating factor 1 (CSF1) and interleukin 34 (IL34) signal via the CSF1 receptor to regulate macrophage differentiation. Studies in IL34- or CSF1-deficient mice have revealed that IL34 function is limited to the central nervous system and sk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fac9dee7283906729daedd8a3091d3c
https://doi.org/10.3389/fimmu.2019.02019
https://doi.org/10.3389/fimmu.2019.02019