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pro vyhledávání: '"Dina Zuckerman"'
Publikováno v:
American journal of hematology. 45(3)
Platelet function in 16 patients with metastatic renal cell carcinoma and melanoma was studied sequentially over the first 96 hr of treatment with moderate and high-dose interleukin-2 (IL-2). During the first 96 hr of therapy, an increased ex vivo pl
Autor:
Dina Zuckerman, Paolo Alberto Paciucci, Leslie Oleksowicz, James F. Holland, Anthony Colorito, Jacob H. Rand
Publikováno v:
Journal of immunotherapy : official journal of the Society for Biological Therapy. 10(5)
We recently reported that thrombocytopenia and bleeding are often limiting effects of immunotherapy with interleukin-2 (IL-2). In order to understand the mechanisms that lead to this unexpected clinical toxicity, we studied the effects of IL-2 on in