Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Dina Tzemach"'
Autor:
Yuval Avnir, Keren Turjeman, Deborah Tulchinsky, Alex Sigal, Pablo Kizelsztein, Dina Tzemach, Alberto Gabizon, Yechezkel Barenholz
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25721 (2011)
We report here the design, development and performance of a novel formulation of liposome- encapsulated glucocorticoids (GCs). A highly efficient (>90%) and stable GC encapsulation was obtained based on a transmembrane calcium acetate gradient drivin
Externí odkaz:
https://doaj.org/article/44c7dc348cca484491d1671a0c8e1def
Autor:
Patricia Ohana, Yasmine Amitay, Lidia Mak, Hilary Shmeeda, Jenny Gorin, Alberto A. Gabizon, Dina Tzemach
Publikováno v:
Cancer drug resistance (Alhambra, Calif.). 4(2)
Autor:
Patricia Ohana, Yogita Patil, Lidia Mak, Hilary Shmeeda, Alberto Gabizon, Jenny Gorin, Yasmine Amitay, Dina Tzemach
Publikováno v:
Pharmaceutical Research. 33:686-700
Pegylated liposomal (PL) mitomycin C lipid-based prodrug (MLP) has recently entered clinical testing. We studied here the preclinical pharmacology of PL-MLP. The stability, pharmacokinetics, biodistribution, and other pharmacologic parameters of PL-M
Publikováno v:
Journal of Controlled Release. 167:265-275
Background Zoledronic acid (Zol) is a potent inhibitor of farnesyl-pyrophosphate synthase with broad clinical use in the treatment of osteoporosis, and bone metastases. We have previously shown that encapsulation of Zol in liposomes targeted to the f
Autor:
Stephan T. Stern, Alberto Gabizon, Yasmine Amitay, Lidia Mak, Hilary Shmeeda, Yechezkel Barenholz, Jenny Gorin, Dina Tzemach
Publikováno v:
Journal of drug targeting. 24(9)
We developed a pegylated liposome formulation of a dissociable salt of a nitrogen-containing bisphosphonate, alendronate (Ald), coencapsulated with the anthracycline, doxorubicin (Dox), a commonly used chemotherapeutic agent. Liposome-encapsulated am
Publikováno v:
Journal of Controlled Release. 160:245-253
Background A mitomycin-C lipid-based prodrug (MLP) formulated in pegylated liposomes (PL-MLP) was previously reported to have significant antitumor activity and reduced toxicity in mouse tumor models (Clin Cancer Res 12:1913–20, 2006). MLP is activ
Autor:
Dina Tzemach, Jenny Gorin, Lidia Mak, Hilary Shmeeda, Samuel Zalipsky, Yasmine Amitay, Alberto Gabizon
Publikováno v:
Cancer Chemotherapy and Pharmacology. 66:43-52
The folate receptor (FR) is overexpressed in a broad spectrum of malignant tumors and represents an attractive target for selective delivery of anti-cancer agents to FR-expressing tumors. Targeting liposomes to the FR has been proposed as a way to en
Publikováno v:
Journal of Controlled Release. 136:155-160
Background Receptor-directed targeting of ligand-bearing liposomes to tumor cells may enhance therapeutic efficacy by intracellular delivery of a concentrated payload of liposomal drug. The goal of this study was to assess whether Her2-targeted pegyl
Publikováno v:
Journal of Computational Acoustics. 15:1-22
The scalar wave equation in a two-dimensional semi-infinite wave guide is considered. The recently proposed Hagstrom–Warburton (H–W) local high-order absorbing boundary conditions (ABCs), which are based on a modification of the Higdon ABCs, are
Autor:
Alberto Gabizon, Dina Tzemach, Deborah Tulchinsky, Alex Sigal, Yechezkel Barenholz, Pablo Kizelsztein, Keren Turjeman, Yuval Avnir
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25721 (2011)
PLoS ONE
PLoS ONE
We report here the design, development and performance of a novel formulation of liposome- encapsulated glucocorticoids (GCs). A highly efficient (>90%) and stable GC encapsulation was obtained based on a transmembrane calcium acetate gradient drivin