Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Dina Ron"'
Autor:
Sabrin Mishel, Boris Shneyer, Lina Korsensky, Orit Goldshmidt-Tran, Tom Haber, Marcelle Machluf, Dina Ron
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Carcinomas constitute over 80% of all human cancer types with no effective therapy for metastatic disease. Here, we demonstrate, for the first time, the efficacy of therapeutic-ultrasound (TUS) to deliver a human tumor suppressor gene, hSef-
Externí odkaz:
https://doaj.org/article/18777b20c254425b9579b5a09b321728
Autor:
Safieh, Jessy, Chazan, Ariel, Saleem, Hanna, Vyas, Pratik, Yael Danin-Poleg, Dina Ron, Haran, Tali E.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 12/5/2023, Vol. 120 Issue 49, p1-9, 22p
Autor:
Shiri Rabinovitz, Dina Ron, Lina Korsensky, Romina Heller, Sasha Haif, Nitsan Dahan, Jumana Haddad-Halloun
Publikováno v:
Cellular Signalling. 59:110-121
The classical NF-κB transcription factor (RelA:p50) and the tumor suppressor Sef axis constitute a negative regulatory loop in which Sef, a target of NF-κB/RelA:p50, fine-tunes NF-κB/RelA:p50 transcriptional-activation in response to inflammatory
Autor:
Marcelle Machluf, Orit Goldshmidt-Tran, Sabrin Mishel, Lina Korsensky, Boris Shneyer, Tom Haber, Dina Ron
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Scientific Reports
Carcinomas constitute over 80% of all human cancer types with no effective therapy for metastatic disease. Here, we demonstrate, for the first time, the efficacy of therapeutic-ultrasound (TUS) to deliver a human tumor suppressor gene, hSef-b, to pro
Autor:
Sagit-Sela Abramovich, Shiri Rabinovitz, Ela Lutwak, Irit Granot, Nava Dekel, Dina Ron, Christopher A Price
Publikováno v:
REPRODUCTION. 148:507-517
Similar expression to FGF (SEF or IL17RD), is a tumor suppressor and an inhibitor of growth factors as well as of pro-inflammatory cytokine signaling. In this study, we examined the regulation ofSefexpression by gonadotropins during ovarian folliculo
Autor:
Ron N. Apte, Amir Orian, Lina Korsensky, Jumana Haddad, Yaron Fuchs, Dina Ron, Simona Zisman-Rozen, Michal Brunwasser, Ruey-Bing Yang, Yaron Carmi, Lilach Koren, Sasha Haif, Jacob Bejar, Boris Shneyer, Orit Goldshmidt-Tran, Mona Abed
Publikováno v:
Developmental Cell. 23:611-623
Summary The NF-κB transcription factor controls diverse biological processes. According to the classical model, NF-κB is retained in the cytoplasm of resting cells via binding to inhibitory, IκB proteins and translocates into the nucleus upon thei
Autor:
Matthias H. Kraus, J Bejar, A Brodski, Yaron Fuchs, Dina Ron, D Fink, Simona Zisman-Rozen, O Ben-Izhak
Publikováno v:
Oncogene. 26:6093-6098
Carcinomas are tumors of epithelial origin accounting for over 80% of all human malignancies. A substantial body of evidence implicates oncogenic signaling by receptor tyrosine kinases (RTKs) in carcinoma development. Here we investigated the express
Autor:
Naama Dym, Tal Zilpa, Dina Ron, Inbal Ziv, Ariel Shabtay, Haggar Harduf, Ella Preger, Yaron Fuchs
Publikováno v:
Journal of Biological Chemistry. 281:39225-39235
Negative feedback is among the key mechanisms for regulating receptor tyrosine kinase (RTK) signaling. Human Sef, a recently identified inhibitor of RTK signaling, encodes different isoforms, including a membrane spanning (hSef-a) and a cytosolic (hS
Autor:
Ifat Sher, Ines Miselevich, Orit Goldshmidt, Ron Shaoul, Yaheli Hamlet, Dina Ron, Liat Eliahu
Publikováno v:
Biochemical and Biophysical Research Communications. 350:825-833
Growth alterations within the gastric mucosa during chronic gastric inflammation are key steps in gastric cancer development. FGF7, a specific mitogen for epithelial cells, is implicated in epithelial tissue repair and cancer. We investigated FGF7 ex
Autor:
Ifat Sher, Yoshihiko Yamada, Dirk Breitkreutz, Norbert E. Fusenig, Simona Zisman-Rozen, John M. Whitelock, Dina Ron, Renato V. Iozzo, Liat Eliahu, Reuven Bergman, Nicole Maas-Szabowski, Eri Arikawa-Hirasawa
Publikováno v:
Journal of Biological Chemistry. 281:5178-5187
Heparin-binding growth factors are crucial for the formation of human epidermis, but little is known about the role of heparan sulfate proteoglycans in this process. Here we investigated the role of the heparan sulfate proteoglycan, perlecan, in the