Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Dina Popova"'
Publikováno v:
Current Research in Neurobiology, Vol 4, Iss , Pp 100069- (2023)
Primary neuronal cultures have proven to be a powerful tool for studying mechanisms in neuroscience. It is technically challenging and expensive to reproduce high quality viable neuronal cultures. Laboratories that are not experienced or equipped to
Externí odkaz:
https://doaj.org/article/e925d087ab8746e8a3786a1a3d8bc932
Autor:
Hanna Antila, Maria Ryazantseva, Dina Popova, Pia Sipilä, Ramon Guirado, Samuel Kohtala, Ipek Yalcin, Jesse Lindholm, Liisa Vesa, Vinicius Sato, Joshua Cordeira, Henri Autio, Mikhail Kislin, Maribel Rios, Sâmia Joca, Plinio Casarotto, Leonard Khiroug, Sari Lauri, Tomi Taira, Eero Castrén, Tomi Rantamäki
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract A brief burst-suppressing isoflurane anesthesia has been shown to rapidly alleviate symptoms of depression in a subset of patients, but the neurobiological basis of these observations remains obscure. We show that a single isoflurane anesthe
Externí odkaz:
https://doaj.org/article/9b0a9c01a2904ac9a4a5d9e945138f61
Publikováno v:
BMC Pharmacology and Toxicology, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract Background Exposure to chemicals might be toxic to the developing brain. There is a need for simple and robust in vitro cellular models for evaluation of chemical-induced neurotoxicity as a complement to traditional studies on animals. In th
Externí odkaz:
https://doaj.org/article/d262b54aff564407a752b7e214dac904
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166750 (2016)
3,4-methylenedioxymethamphetamine (MDMA; ecstasy) is a commonly abused recreational drug that causes neurotoxic effects in both humans and animals. The mechanism behind MDMA-induced neurotoxicity is suggested to be species-dependent and needs to be f
Externí odkaz:
https://doaj.org/article/6824adfc5a0f458286cae36b6c8c7d88
Autor:
Fulin Ma, Himanshu Akolkar, Jianquan Xu, Yang Liu, Dina Popova, Jiaan Xie, Mark M. Youssef, Ryad Benosman, Ronald P. Hart, Karl Herrup
Publikováno v:
The Journal of Neuroscience. 43:1830-1844
The amyloid precursor protein (APP) is linked to the genetics and pathogenesis of Alzheimer's disease (AD). It is the parent protein of the β-amyloid (Aβ) peptide, the main constituent of the amyloid plaques found in an AD brain. The pathways from
Autor:
Iya Prytkova, Yiyuan Liu, Michael Fernando, Isabel Gameiro-Ros, Dina Popova, Chella Kamarajan, Xiaoling Xuei, David B. Chorlian, Howard J. Edenberg, Jay A. Tischfield, Bernice Porjesz, Zhiping P. Pang, Ronald P. Hart, Alison Goate, Paul A. Slesinger
Publikováno v:
bioRxiv
SUMMARYGenome-wide association analysis of electroencephalographic endophenotypes for alcohol use disorder has identified non-coding polymorphisms within theKCNJ6gene.KCNJ6encodes the GIRK2 protein, a subunit of a G-protein-coupled inwardly-rectifyin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e14fcd5e6cb7ed030584e557640734
https://europepmc.org/articles/PMC10055374/
https://europepmc.org/articles/PMC10055374/
Autor:
Dina Popova, Isabel Gameiro-Ros, Mark M. Youssef, Petronio Zalamea, Ayeshia D. Morris, Iya Prytkova, Azadeh Jadali, Kelvin Y. Kwan, Chella Kamarajan, Jessica E. Salvatore, Xiaoling Xuei, David B. Chorlian, Bernice Porjesz, Samuel Kuperman, Danielle M. Dick, Alison Goate, Howard J. Edenberg, Jay A. Tischfield, Zhiping P. Pang, Paul A. Slesinger, Ronald P. Hart
Publikováno v:
Molecular psychiatry.
Synonymous and noncoding single nucleotide polymorphisms (SNPs) in the KCNJ6 gene, encoding G protein-gated inwardly rectifying potassium (GIRK2) channel subunit 2, have been linked with increased electroencephalographic frontal theta event-related o
The small Aβ peptide has been hypothesized to be the main driver of Alzheimer’s disease (AD). Aβ is a proteolytic cleavage product of a larger protein, the amyloid precursor protein (APP), whose normal functions remain largely unexplored. We repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd293c87178374246c4b30b06b1b446c
https://doi.org/10.1101/2022.01.23.477413
https://doi.org/10.1101/2022.01.23.477413
Publikováno v:
The Journal of Neuroscience. 39:5685-5696
Mu-opioid receptors (MORs) are the primary site of action of opioid drugs, both licit and illicit. Susceptibility to opioid addiction is associated with variants in the gene encoding the MOR, OPRM1. Varying with ethnicity, ∼25% of humans carry a si
Autor:
Ramon Guirado, Sari E. Lauri, Vinicius Sato, Mikhail Kislin, Liisa Vesa, Maria Ryazantseva, Leonard Khiroug, Sâmia R.L. Joca, Jesse Lindholm, Joshua Cordeira, Ipek Yalcin, Eero Castrén, Pia Sipilä, Dina Popova, Plinio C. Casarotto, Tomi Rantamäki, Samuel Kohtala, Henri Autio, Hanna Antila, Maribel Rios, Tomi Taira
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Antila, H, Ryazantseva, M, Popova, D, Sipilä, P, Guirado, R, Kohtala, S, Yalcin, I, Lindholm, J, Vesa, L, Sato, V, Cordeira, J, Autio, H, Kislin, M, Rios, M, Joca, S, Casarotto, P, Khiroug, L, Lauri, S, Taira, T, Castrén, E & Rantamäki, T 2017, ' Isoflurane produces antidepressant effects and induces TrkB signaling in rodents ', Scientific Reports, vol. 7, no. 1, pp. 7811 . https://doi.org/10.1038/s41598-017-08166-9
Scientific Reports
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Antila, H, Ryazantseva, M, Popova, D, Sipilä, P, Guirado, R, Kohtala, S, Yalcin, I, Lindholm, J, Vesa, L, Sato, V, Cordeira, J, Autio, H, Kislin, M, Rios, M, Joca, S, Casarotto, P, Khiroug, L, Lauri, S, Taira, T, Castrén, E & Rantamäki, T 2017, ' Isoflurane produces antidepressant effects and induces TrkB signaling in rodents ', Scientific Reports, vol. 7, no. 1, pp. 7811 . https://doi.org/10.1038/s41598-017-08166-9
A brief burst-suppressing isoflurane anesthesia has been shown to rapidly alleviate symptoms of depression in a subset of patients, but the neurobiological basis of these observations remains obscure. We show that a single isoflurane anesthesia produ