Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Dina Polyak"'
Autor:
Irene Scarfò, Stephen Santoro, Aaron Cooper, Jun Feng, Dina Polyak, Michelle Nguyen, James Zhang, Hongruo Yun, Jasper Williams, Jessica Fuhriman, Jennifer McDevitt
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/8e6c0996f9bb47a1a706990875c81c33
Autor:
Yingmei Li, Dina Polyak, Layton Lamsam, Ian David Connolly, Eli Johnson, Lina Khav Khoeur, Stephanie Andersen, Monica Granucci, Geoff Stanley, Boxiang Liu, Seema Nagpal, Melanie Hayden Gephart
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-8 (2021)
Abstract Non-small cell lung cancer (NSCLC) metastatic to the brain leptomeninges is rapidly fatal, cannot be biopsied, and cancer cells in the cerebrospinal fluid (CSF) are few; therefore, available tissue samples to develop effective treatments are
Externí odkaz:
https://doaj.org/article/e3071f0cb1e5411ca282118af6fa15b4
Autor:
Jason Hall, Stephen Santoro, Aaron Cooper, Natalie Bezman, Jun Feng, Kanika Chawla, Jaspar Williams, John Gagnon, Dina Polyak, Angela Boroughs, Michelle Nguyen, Suchismita Mohanty, Adam Litterman, Jeff Granja, David DeTomaso, Grace Zheng, Jenessa Smith, Drake LeFace, Tarjei Mikkelsen, Susie Jun
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/3de68468bbeb414eb0074915461c96fd
Autor:
Alice Chang, Sophia Phillips, Max Lee, Elizabeth Huang, Navneet Anand, Hayden Ko, Stella Tran, Lindsay Rios, Rory Dai, Anton Nguyen, Anu Vasudevan, Rona Harari Steinfeld, Dina Polyak, Jessica Fuhriman, Hongruo Yun, Jun Feng, Haixia Wang, Ben Tran, Jenessa Smith, Tim Sirichoke
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Melanie Hayden Gephart, Derek Yecies, Steven Chu, Saba Shevidi, Yilei Li, Dina Polyak, Eli Johnson, Adam de la Zerda
Publikováno v:
IEEE Trans Med Imaging
Conventional ultrasound imaging is based on the scattering of sound from inhomogeneities in the density and the speed of sound and is often used in medicine to resolve pathologic compared to normal tissue. Here we demonstrate a difference-frequency u
Autor:
Jun Feng, Drake LeFace, Aaron Cooper, Michelle L.T. Nguyen, Suchismita Mohanty, Angela C. Boroughs, Jason F. Hall, Adam J. Litterman, Jenessa B. Smith, Jeff Granja, Dina Polyak, John D. Gagnon, Jaspar Williams, Kanika Chawla, Susie Jun, Stephen Santoro, Tarjei S. Mikkelsen, Grace X.Y. Zheng, Natalie Bezman, David DeTomaso
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundIn solid tumors, CAR T cell efficacy is limited by off-tumor toxicity and suppression by the tumor microenvironment (TME). AB-X is an integrated circuit T cell (ICT cell) intended for the treatment of ovarian cancer. AB-X includes a transge
Autor:
Monica Granucci, Stephanie Andersen, Lina Khoeur, Eli Johnson, Dina Polyak, Geoff Stanley, Layton Lamsam, Boxiang Liu, Ian D. Connolly, Seema Nagpal, Melanie Hayden Gephart, Yingmei Li
Publikováno v:
NPJ Precision Oncology
npj Precision Oncology, Vol 5, Iss 1, Pp 1-8 (2021)
npj Precision Oncology, Vol 5, Iss 1, Pp 1-8 (2021)
Non-small cell lung cancer (NSCLC) metastatic to the brain leptomeninges is rapidly fatal, cannot be biopsied, and cancer cells in the cerebrospinal fluid (CSF) are few; therefore, available tissue samples to develop effective treatments are severely
Autor:
John Gagnon, Adam J. Litterman, Jason A. Hall, Dina Polyak, Stanley Zhou, Sahil Joshi, Oliver Takacsi-Nagy, Hans Pope, luisa silva, brenal K. Singh, jeffrey M. Granja, david DeTomaso, Edgar Aristil-Lepe, Michelle Tan, Brendan Galvin, Grace X. Zheng, Stephen Santoro, Aaron Cooper, Natalie Bezman, W Nicholas Haining
Publikováno v:
Cancer Research. 82:2830-2830
Cell therapies have shown limited efficacy in solid tumors, in part due to limitations in CAR T cell survival, expansion, and resistance to immunosuppressive pathways operating in the tumor microenvironment (TME). To overcome these hurdles, we screen
Autor:
Jasper Williams, Kevin Martinez, Angela Boroughs, Laura Lim, Marian Sandoval, Cate Sue, Matthew Drever, Anzhi Yao, Joseph Choe, Maxim Sidorov, Sophia Phillips, Dina Polyak, Suchismita Mohanty, Stephen Santoro, Aaron Cooper, W. Nicholas Haining
Publikováno v:
Cancer Research. 82:2854-2854
CAR T cell therapies for solid tumors are limited by a paucity of tumor-specific single target antigens and insufficient potency due to limitations of CAR T biology. Logic gated (LG) CARs increase control of cell therapy activation and target cell ki
CMET-27. EVALUATION OF DYNAMIN 2 (DNM2) AS A THERAPEUTIC TARGET IN LEPTOMENINGEAL METASTATIC DISEASE
Autor:
Dina Polyak, Eli Johnson, Lina Khoeur, Rie von Eyben, Ian D. Connolly, Jiaojiao Deng, Geoff Stanley, Hriday P. Bhambhvani, Kevin Tran, Yingmei Li, Annie Joyce, Sheila Tsau, Kerriann M. Casey, Sophia B. Chernikova, Seema Nagpal, Melanie Hayden Gephart
Publikováno v:
Neuro Oncol
Leptomeningeal metastasis (LM), a spread of cancer to the meninges and cerebrospinal fluid, carries extremely poor prognosis due to fast progression and no effective treatment. Given that LM mostly develops in specific types of cancer, notably melano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eef88e1f918809c6476a480ca175dee
https://europepmc.org/articles/PMC6847315/
https://europepmc.org/articles/PMC6847315/