Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Dina P. Matheos"'
Autor:
Ashley A. Keiser, Tri N. Dong, Enikö A. Kramár, Christopher W. Butler, Siwei Chen, Dina P. Matheos, Jacob S. Rounds, Alyssa Rodriguez, Joy H. Beardwood, Agatha S. Augustynski, Ameer Al-Shammari, Yasaman Alaghband, Vanessa Alizo Vera, Nicole C. Berchtold, Sharmin Shanur, Pierre Baldi, Carl W. Cotman, Marcelo A. Wood
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Exercise has beneficial effects on cognition throughout the lifespan. Here, we demonstrate that specific exercise patterns transform insufficient, subthreshold training into long-term memory in mice. Our findings reveal a potential molecular
Externí odkaz:
https://doaj.org/article/883add3029f74138861d225be22db9ea
Autor:
Stefania Forner, Shimako Kawauchi, Gabriela Balderrama-Gutierrez, Enikö A. Kramár, Dina P. Matheos, Jimmy Phan, Dominic I. Javonillo, Kristine M. Tran, Edna Hingco, Celia da Cunha, Narges Rezaie, Joshua A. Alcantara, David Baglietto-Vargas, Camden Jansen, Jonathan Neumann, Marcelo A. Wood, Grant R. MacGregor, Ali Mortazavi, Andrea J. Tenner, Frank M. LaFerla, Kim N. Green
Publikováno v:
Scientific Data, Vol 8, Iss 1, Pp 1-16 (2021)
Measurement(s) Protein Expression • gene expression • electrophysiology data • protein measurement • behavior Technology Type(s) immunofluorescence microscopy assay • RNA sequencing • electrophysiology assay • Electrochemiluminescence I
Externí odkaz:
https://doaj.org/article/b2396bfe67d3413cbec4c74a4d952aef
Autor:
David Baglietto-Vargas, Stefania Forner, Lena Cai, Alessandra C. Martini, Laura Trujillo-Estrada, Vivek Swarup, Marie Minh Thu Nguyen, Kelly Do Huynh, Dominic I. Javonillo, Kristine Minh Tran, Jimmy Phan, Shan Jiang, Enikö A. Kramár, Cristina Nuñez-Diaz, Gabriela Balderrama-Gutierrez, Franklin Garcia, Jessica Childs, Carlos J. Rodriguez-Ortiz, Juan Antonio Garcia-Leon, Masashi Kitazawa, Mohammad Shahnawaz, Dina P. Matheos, Xinyi Ma, Celia Da Cunha, Ken C. Walls, Rahasson R. Ager, Claudio Soto, Antonia Gutierrez, Ines Moreno-Gonzalez, Ali Mortazavi, Andrea J. Tenner, Grant R. MacGregor, Marcelo Wood, Kim N. Green, Frank M. LaFerla
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Most instances of Alzheimer’s disease (AD) are sporadic or not associated with a particular mutation. Here, the authors develop knock-in mice that express wildtype human Aβ under control of the mouse App locus, which may have potential for modelli
Externí odkaz:
https://doaj.org/article/1e311a8bbdd34a96bb987b252f4dfaaf
Autor:
Dominic I. Javonillo, Kristine M. Tran, Jimmy Phan, Edna Hingco, Enikö A. Kramár, Celia da Cunha, Stefania Forner, Shimako Kawauchi, Giedre Milinkeviciute, Angela Gomez-Arboledas, Jonathan Neumann, Crystal E. Banh, Michelle Huynh, Dina P. Matheos, Narges Rezaie, Joshua A. Alcantara, Ali Mortazavi, Marcelo A. Wood, Andrea J. Tenner, Grant R. MacGregor, Kim N. Green, Frank M. LaFerla
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2022)
Animal models of disease are valuable resources for investigating pathogenic mechanisms and potential therapeutic interventions. However, for complex disorders such as Alzheimer’s disease (AD), the generation and availability of innumerous distinct
Externí odkaz:
https://doaj.org/article/677dc4105eff49cab8550eb3df2b59bd
Autor:
Andra Ionescu-Tucker, Christopher W. Butler, Nicole C. Berchtold, Dina P. Matheos, Marcelo A. Wood, Carl W. Cotman
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Exercise improves cognition in the aging brain and is a key regulator of neuronal plasticity genes such as BDNF. However, the mechanism by which exercise modifies gene expression continues to be explored. The repressive histone modification H3K9me3 h
Externí odkaz:
https://doaj.org/article/08f0a863f4714ce0a19cea8bcaa589d1
Autor:
Janine L. Kwapis, Yasaman Alaghband, Enikö A. Kramár, Alberto J. López, Annie Vogel Ciernia, André O. White, Guanhua Shu, Diane Rhee, Christina M. Michael, Emilie Montellier, Yu Liu, Christophe N. Magnan, Siwei Chen, Paolo Sassone-Corsi, Pierre Baldi, Dina P. Matheos, Marcelo A. Wood
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Circadian rhythms are known to modulate memory, but it’s not known whether clock genes in the hippocampus are required for memory consolidation. Here, the authors show that epigenetic regulation of clock gene Period1 in the hippocampus regulates me
Externí odkaz:
https://doaj.org/article/8214879eac4444f79329a0009fdad2ee
Autor:
André O. White, Enikö A. Kramár, Alberto J. López, Janine L. Kwapis, John Doan, David Saldana, M. Felicia Davatolhagh, Yasaman Alaghband, Mathew Blurton-Jones, Dina P. Matheos, Marcelo A. Wood
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Epigenetic mechanisms play a key role in drug-associated memories and behaviors. Here authors show that mice deficient of BAF53b, a nucleosome remodeling complex subunit, display deficits in synaptic plasticity and cocaine-associated memory, both of
Externí odkaz:
https://doaj.org/article/37dbd22580704fe786b26acb2218046b
Autor:
Lilyana V. Pham, Rianne R. Campbell, Alberto J. López, Siwei Chen, Dina P. Matheos, Marcelo A. Wood, Vivek Swarup, Joy H. Beardwood, Ashley M. Keiser, Jessica E. Childs, Pierre Baldi
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, vol 46, iss 10
Neuropsychopharmacology
Neuropsychopharmacology
During the initial stages of drug use, cocaine-induced neuroadaptations within the ventral tegmental area (VTA) are critical for drug-associated cue learning and drug reinforcement processes. These neuroadaptations occur, in part, from alterations to
Autor:
A S Augustynski, Rianne R. Campbell, J Banihani, L Pham, Enikö A. Kramár, Om Chitnis, Dina P. Matheos, J H Beardwood, Alberto J. López, G Delima, Marcelo A. Wood
Publikováno v:
The Journal of Neuroscience
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 41, iss 13
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 41, iss 13
Epigenetic mechanisms regulate processes of neuroplasticity critical to cocaine-induced behaviors. This includes the Class I histone deacetylase (HDAC) HDAC3, known to act as a negative regulator of cocaine-associated memory formation within the nucl
Autor:
Dominic I. Javonillo, Kristine M. Tran, Jimmy Phan, Edna Hingco, Enikö A. Kramár, Celia da Cunha, Stefania Forner, Shimako Kawauchi, Jonathan Neumann, Crystal E. Banh, Michelle Huynh, Dina P. Matheos, Narges Rezaie, Joshua A. Alcantara, Ali Mortazavi, Marcelo A. Wood, Andrea J. Tenner, Grant R. MacGregor, Kim N. Green, Frank M. LaFerla
Animal models of disease are valuable resources for investigating pathogenic mechanisms and potential therapeutic interventions. However, for complex disorders such as Alzheimer’s disease (AD), the generation and availability of innumerous distinct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94ade48321cfcfd85cb03139b1340bb0
https://doi.org/10.1101/2021.10.01.462640
https://doi.org/10.1101/2021.10.01.462640