Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Dina Morshedi"'
Autor:
Maryam Khaleghi, Fakhri Haghi, Mina Gholami, Hamdam Hourfar, Farshad Shahi, Ali Mir Mousavi Zekoloujeh, Farhang Aliakbari, Ebrahim Ahmadi, Dina Morshedi
Publikováno v:
AMB Express, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract High risk of acute morbidities and even mortality from expanding the antibiotics resistant infectious wounds force indefinite efforts for development of high performance wound-healing materials. Herein, we design a procedure to fabricate a h
Externí odkaz:
https://doaj.org/article/a3f83ef4414845ecbeeb187e3b4e93f5
Autor:
Zahra Nayeri, Farhang Aliakbari, Farzaneh Afzali, Soha Parsafar, Ehsan Gharib, Daniel E. Otzen, Dina Morshedi
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Despite extensive research, the molecular mechanisms underlying the toxicity of αSN in Parkinson’s disease (PD) pathology are still poorly understood. To address this, we used a microarray dataset to identify genes that are induced and differentia
Externí odkaz:
https://doaj.org/article/7f52cb14bb564d0e85ae8119564a3f87
Autor:
Mahdieh Sashourpour, Dina Morshedi, Saber Zahri, Farhang Ali akbari, Marzieh Fottovat, Tayebeh Rajabian
Publikováno v:
Journal of Medicinal Plants, Vol 18, Iss 69, Pp 34-46 (2019)
Many of neurodegenerative diseases (NDs) are associated with formation of the protein aggregates called amyloidal fibrils. Fibrillization of alpha-synuclein seems to be a key stage in the creation and progression of NDs and finding the compounds that
Externí odkaz:
https://doaj.org/article/299a03d492c446f980ff9f99c46a3d1a
Autor:
Soha Parsafar, Zahra Nayeri, Farhang Aliakbari, Farshad Shahi, Mehdi Mohammadi, Dina Morshedi
Publikováno v:
Heliyon, Vol 6, Iss 8, Pp e04737- (2020)
Parkinson's disease (PD) is one of the most prevalent neurodegenerative disorders with no precise etiology. Multiple lines of evidence support that environmental factors, either neurotoxins or neuroinflammation, can induce Parkinsonism. In this study
Externí odkaz:
https://doaj.org/article/7a1dfc1bffad4752bfc8f3039210ba82
Autor:
Maryam Khaleghi, Ebrahim Ahmadi, Mahvash Khodabandeh Shahraki, Farhang Aliakbari, Dina Morshedi
Publikováno v:
Heliyon, Vol 6, Iss 3, Pp e03494- (2020)
Hyaluronic acid (HA), as a safe biomaterial with minimal immunogenicity, is being employed in a broad range of medical applications. Since unmodified HA has a high potential for biodegradation in the physiological condition, herein, an HA-based cross
Externí odkaz:
https://doaj.org/article/3a0612a2d3874a3cad173e4bcca11142
Autor:
Mahdyeh Sashourpour, Saber Zahri, Tayebeh Radjabian, Viktoria Ruf, Francisco Pan-Montojo, Dina Morshedi
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184483 (2017)
Aggregation of alpha-synuclein (α-SN) is a key pathogenic event in Parkinson's disease (PD) leading to dopaminergic degeneration. The identification of natural compounds inhibiting α-SN aggregation may have a major role in treating PD. Different Sc
Externí odkaz:
https://doaj.org/article/a6bb8703391644fc8631db39117021f4
Autor:
Farhang Aliakbari, Seyedeh Felour Mazhar, Rouhollah Karami-Osboo, Parvin Shariati, Dina Morshedi, Davoud Farajzadeh
Publikováno v:
Novelty in Biomedicine, Vol 2, Iss 2, Pp 36-46 (2014)
Background: Essential oils and their major constituents are useful sources of antimicrobial compounds. There are a few reports on the decontamination and antimicrobial activity of essential oils towards Shigella spp.Materials and Methods: In this stu
Externí odkaz:
https://doaj.org/article/a3028f302a964fe088ec98c0d2ef9fc7
Autor:
Zahra Najarzadeh, Hossein Mohammad-Beigi, Jannik Nedergaard Pedersen, Gunna Christiansen, Thorbjørn Vincent Sønderby, Seyed Abbas Shojaosadati, Dina Morshedi, Kristian Strømgaard, Georg Meisl, Duncan Sutherland, Jan Skov Pedersen, Daniel E. Otzen
Publikováno v:
Biomolecules, Vol 9, Iss 11, p 659 (2019)
Self-assembly of proteins to β-sheet rich amyloid fibrils is commonly observed in various neurodegenerative diseases. However, amyloid also occurs in the extracellular matrix of bacterial biofilm, which protects bacteria from environmental stress an
Externí odkaz:
https://doaj.org/article/bbf2bc4a8ca04960946786765ab495de
Autor:
Dina Morshedi, Mahour Nasouti
Publikováno v:
Parkinson's Disease, Vol 2016 (2016)
α-Synuclein (α-Syn) fibrillation links with Parkinson’s disease (PD) and several related syndromes. It is believed that exposure to the factors which promote fibrillation may induce and progress such neurodegenerative diseases (NDs). Herein, the
Externí odkaz:
https://doaj.org/article/2ab4e490dfa8457e91e6d8bf5af7217d
Autor:
Soha Parsafar, Farhang Aliakbari, Sepideh Sadat Seyedfatemi, Zahra Najarzadeh, Hamdam Hourfar, Hassan Bardania, Mohsen Farhadpour, Mehdi Mohammadi, Dina Morshedi
Publikováno v:
Parsafar, S, Aliakbari, F, Seyedfatemi, S S, Najarzadeh, Z, Hourfar, H, Bardania, H, Farhadpour, M, Mohammadi, M & Morshedi, D 2022, ' Insights into the inhibitory mechanism of skullcapflavone II against α-synuclein aggregation and its mediated cytotoxicity ', International Journal of Biological Macromolecules, vol. 209, no. Part A, pp. 426-440 . https://doi.org/10.1016/j.ijbiomac.2022.03.092
The dangerous self-assembled and infectious seeds of α-synuclein (αSN) play primary roles in Parkinson's disease. Accordingly, the inhibition of αSN fibrillation and elimination of toxic aggregates are the main therapeutic strategies. Skullcapflav