Výsledky vyhledávání - "Dina M. E. Amin"

Design, synthesis of new anti-inflammatory agents with a pyrazole core: COX-1/COX-2 inhibition assays, anti-inflammatory, ulcerogenic, histopathological, molecular Modeling, and ADME studies

Autor: Eman K. A. Abdelall, Phoebe F. Lamie, El-Shaymaa El-Nahaas, Khaled R.A. Abdellatif, Dina M. E. Amin, Heba A.H. Elshemy

Publikováno v: Journal of Molecular Structure. 1240:130554

Novel anti-inflammatory pyrazole derivatives (4a,b, 5a,b, 6a,b, 7a,b, 8a,b, 11a-c, 12a-c, 13a-c and 14a-c) were designed as coxib analogues, synthesized and evaluated for both in vitro and in vivo inhibitory activity. Compounds 4a, 4b, 5a, 6a, 6b, 13

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::415818707cf5c08f429e4767fbd566e7
https://doi.org/10.1016/j.molstruc.2021.130554

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Design, synthesis and biological evaluation of new 4-(4-substituted-anilino)quinoline derivatives as anticancer agents

Autor: Khaled R.A. Abdellatif, Eman K. A. Abdelall, Mohamed A. Abdelgawad, Hany A. Omar, Dina M. E. Amin

Publikováno v: Medicinal Chemistry Research. 26:929-939

A new series of 4-(4-substituted-anilino)quinoline derivatives 6a–f was synthesized from amine derivatives via Gould–Jacobs reaction. All synthesized compounds were evaluated for their cytotoxic activity against two human cancer cell lines; breas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d5d29a6d8c85559688da3cd848bbb377
https://doi.org/10.1007/s00044-017-1798-9

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