Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Dina Dabaghie"'
Autor:
Dina Dabaghie, Emmanuelle Charrin, Pernilla Tonelius, Birgitta Rosengren, Gizem Korkut, Anna B. Granqvist, Mark Lal, Jaakko Patrakka
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Natriuretic peptides (NPs) are cardio-derived hormones that have a crucial role in maintaining cardiovascular homeostasis. Physiological effects of NPs are mediated by binding to natriuretic peptide receptors 1 and 2 (NPR1/2), whereas natriu
Externí odkaz:
https://doaj.org/article/75df1190c0e3459c94c0b9234d83dafc
Autor:
Emmanuelle Charrin, Dina Dabaghie, Ilke Sen, David Unnersjö-Jess, Katja Möller-Hackbarth, Mikhail Burmakin, Rik Mencke, Sonia Zambrano, Jaakko Patrakka, Hannes Olauson
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Transgenic overexpression of αKlotho in hepatocytes results in protection against renal insults, possibly through modulation of the ER stress response by circulating αKlotho. In contrast, αKlotho overexpressed in podocytes is not renoprotective.
Externí odkaz:
https://doaj.org/article/619b3e82d9e24b86ae6db800031da9d4
Autor:
Bing He, Ping Chen, Sonia Zambrano, Dina Dabaghie, Yizhou Hu, Katja Möller-Hackbarth, David Unnersjö-Jess, Gül Gizem Korkut, Emmanuelle Charrin, Marie Jeansson, Maria Bintanel-Morcillo, Anna Witasp, Lars Wennberg, Annika Wernerson, Bernhard Schermer, Thomas Benzing, Patrik Ernfors, Christer Betsholtz, Mark Lal, Rickard Sandberg, Jaakko Patrakka
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
The molecular identity of renal glomerular cells is poorly characterized and rodent glomerulopathy models translate poorly to humans. Here, the authors show molecular signatures of glomerulus-associated cells using single cell RNA sequencing and high
Externí odkaz:
https://doaj.org/article/fe04160ada134a20a0af7aef65e1f106
Autor:
Guillem Genové, Dina Dabaghie, Jaakko Patrakka, Katja Möller-Hackbarth, Mark Lal, Xidan Li, Annika Wernerson, Sonia Zambrano, Emmanuelle Charrin
Publikováno v:
Kidney International. 100:809-823
Inflammatory pathways are activated in most glomerular diseases but molecular mechanisms driving them in kidney tissue are poorly known. We identified retinoic acid receptor responder 1 (Rarres1) as a highly podocyte-enriched protein in healthy kidne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef24ab6dca4ec5587f0eb43ebbca63f7
https://doi.org/10.1016/j.kint.2021.05.036
https://doi.org/10.1016/j.kint.2021.05.036
Autor:
Dina Dabaghie, Jaakko Patrakka, Katja Möller-Hackbarth, Hannes Olauson, Emmanuelle Charrin, Rik Mencke, Ilke Sen, Sonia Zambrano
Publikováno v:
Nephrology Dialysis Transplantation. 36
Background and Aims Podocyte integrity is crucial for the maintenance of glomerular function in health and disease. Numerous studies have reported that Klotho overexpression, or treatment with recombinant Klotho, reduces glomerular and tubular damage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::947726ffe1b21f0a12248f9a31334e6c
https://doi.org/10.1093/ndt/gfab104.0021
https://doi.org/10.1093/ndt/gfab104.0021
Autor:
Gül Gizem Korkut, Katja Möller-Hackbarth, David Unnersjö-Jess, Annika Wernerson, Yizhou Hu, Sonia Zambrano, Marie Jeansson, Rickard Sandberg, Dina Dabaghie, Emmanuelle Charrin, Ping Chen, Lars Wennberg, Thomas Benzing, Patrik Ernfors, Anna Witasp, Christer Betsholtz, Jaakko Patrakka, Bernhard Schermer, Maria Bintanel-Morcillo, Bing He, Mark Lal
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Molecular characterization of the individual cell types in human kidney as well as model organisms are critical in defining organ function and understanding translational aspects of biomedical research. Previous studies have uncovered gene expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3a4f29f09880dc96b34a15c5c64cda
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-455805
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-455805
Autor:
Frans G. M. Russel, Alexander H. van Asbeck, Janny G. P. Peters, Neslihan N. Tavraz, Rosalinde Masereeuw, Thomas Friedrich, Tom T. G. Nieskens, Martijn J. Wilmer, Daphne Korte, Katja Jansen, Dina Dabaghie
Publikováno v:
Drug Metabolism and Disposition, 46, 592-599
Drug Metabolism and Disposition, 46, 5, pp. 592-599
Drug Metabolism and Disposition, 46, 5, pp. 592-599
Contains fulltext : 193213.pdf (Publisher’s version ) (Open Access) Cisplatin is a cytostatic drug used for treatment of solid organ tumors. The main adverse effect is organic cation transporter 2 (OCT2)-mediated nephrotoxicity, observed in 30% of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095afbd7d7437c076bc1c5acad7a4e00
http://hdl.handle.net/2066/193213
http://hdl.handle.net/2066/193213