Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Dina, Michael S."'
Autor:
Georgette Castanedo, Shirley A. Brunton, Susan Wong, James C. Marsters, Lesley J. Murray, Laurent Salphati, Karen Kotkow, Cyrus Khojasteh, Kevin Lau, Stanley Mark S, Michael F. T. Koehler, Dina Michael S, Lee L. Rubin, Wei Jia, Hank La, Daniel P. Sutherlin, Leslie Lee, Shumei Wang, Jason Halladay, Changgeng Qian, John H. A. Stibbard, Savita Ubhayaker, Janet L. Gunzner, Kirk Robarge, Stephen E. Gould, Oivin Guichert, Minli Xie, Lalonde Rebecca, Richard Goldsmith, Yong Cui, Derek Marshall
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:5576-5581
SAR for a wide variety of heterocyclic replacements for a benzimidazole led to the discovery of functionalized 2-pyridyl amides as novel inhibitors of the hedgehog pathway. The 2-pyridyl amides were optimized for potency, PK, and drug-like properties
Autor:
Robarge, Kirk D., Brunton, Shirley A., Castanedo, Georgette M., Cui, Yong, Dina, Michael S., Goldsmith, Richard, Gould, Stephen E., Guichert, Oivin, Gunzner, Janet L., Halladay, Jason, Jia, Wei, Khojasteh, Cyrus, Koehler, Michael F.T., Kotkow, Karen, La, Hank, LaLonde, Rebecca L., Lau, Kevin, Lee, Leslie, Marshall, Derek, Marsters, James C., Jr., Murray, Lesley J., Qian, Changgeng, Rubin, Lee L., Salphati, Laurent, Stanley, Mark S., Stibbard, John H.A., Sutherlin, Daniel P., Ubhayaker, Savita, Wang, Shumei, Wong, Susan, Xie, Minli
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 2009 19(19):5576-5581
Autor:
Rob Webb, Kirk Robarge, Dina Michael S, Weese Kenneth J, Alan G. Olivero, Todd C. Somers, Brent Blackburn, Ignacio Aliagas, Maureen H. Tischler, Thomas E. Rawson, Arthur Lee
Publikováno v:
Bioorganicmedicinal chemistry. 6(12)
Antagonists of the glycoprotein GPIIb/IIIa are a promising class of antithrombotic agents offering potential advantages over present antiplatelet agents (i.e., aspirin and ticlopidine). Novel tricyclic nonpeptidal GPIIb/IIIa antagonists have been pre
Autor:
Janet L. Gunzner, Dina Michael S, Laurent Salphati, Karen Kotkow, James C. Marsters, Richard Goldsmith, Lesley J. Murray, Yong Cui, Hank La, Wei Jia, Jason Halladay, Kirk Robarge, Daniel P. Sutherlin, Lalonde Rebecca, Derek Marshall, Savita Ubhayaker, Shirley A. Brunton, Changgeng Qian, John H. A. Stibbard, Georgette Castanedo, Susan Wong, Leslie Lee, Cyrus Khojasteh, Lee L. Rubin, Shumei Wang, Stanley Mark S, Michael F. T. Koehler, Kevin Lau, Stephen E. Gould, Oivin Guichert, Minli Xie
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:771
Kirk D. Robarge *, Shirley A. Brunton , Georgette M. Castanedo , Yong Cui , Michael S. Dina , Richard Goldsmith , Stephen E. Gould , Oivin Guichert , Janet L. Gunzner , Jason Halladay , Wei Jia , Cyrus Khojasteh , Michael F. T. Koehler , Karen Kotkow
Autor:
Robarge, Kirk D., Brunton, Shirley A., Castanedo, Georgette M., Cui, Yong, Dina, Michael S., Goldsmith, Richard, Gould, Stephen E., Guichert, Oivin, Gunzner, Janet L., Halladay, Jason, Jia, Wei, Khojasteh, Cyrus, Koehler, Michael F.T., Kotkow, Karen, La, Hank, LaLonde, Rebecca L., Lau, Kevin, Lee, Leslie, Marshall, Derek, Marsters, James C., Jr., Murray, Lesley J., Qian, Changgeng, Rubin, Lee L., Salphati, Laurent, Stanley, Mark S., Stibbard, John H.A., Sutherlin, Daniel P., Ubhayaker, Savita, Wang, Shumei, Wong, Susan, Xie, Minli
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 2010 20(2):771-771
Autor:
Robarge, Kirk D., Dina, Michael S., Somers, Todd C., Lee, Arthur, Rawson, Thomas E., Olivero, Alan G., Tischler, Maureen H., Webb, Robert R., Weese, Kenneth J., Aliagas, Ignacio, Blackburn, Brent K.
Publikováno v:
Bioorganic & Medicinal Chemistry; 1998, Vol. 6 Issue: 12 p2345-2381, 37p
Akademický článek
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Autor:
Mylari, Banavara L., Oates, Peter J., Beebe, David A., Brackett, Nathaniel S., Coutcher, James B., Dina, Michael S., Zembrowski, William J.
Publikováno v:
ChemInform; Dec2001, Vol. 32 Issue 49, pno-no, 1p
Autor:
Mylari BL; Pfizer Global Research and Development, Pfizer Inc., Groton, Connecticut 06340, USA. blmylari@aol.com, Armento SJ, Beebe DA, Conn EL, Coutcher JB, Dina MS, O'Gorman MT, Linhares MC, Martin WH, Oates PJ, Tess DA, Withbroe GJ, Zembrowski WJ
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2005 Oct 06; Vol. 48 (20), pp. 6326-39.
Autor:
Mylari BL; Pfizer Global Research and Development, Pfizer Inc., Groton, Connecticut 06340, USA. blmylari@aol.com, Armento SJ, Beebe DA, Conn EL, Coutcher JB, Dina MS, O'Gorman MT, Linhares MC, Martin WH, Oates PJ, Tess DA, Withbroe GJ, Zembrowski WJ
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2003 Jun 05; Vol. 46 (12), pp. 2283-6.