Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Din Selmanovic"'
Autor:
Stuart B. Fass, Bernard Mulvey, Rebecca Chase, Wei Yang, Din Selmanovic, Sneha M. Chaturvedi, Eric Tycksen, Lauren A. Weiss, Joseph D. Dougherty
Publikováno v:
Biology of Sex Differences, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Background Sex differences in the brain may play an important role in sex-differential prevalence of neuropsychiatric conditions. Methods In order to understand the transcriptional basis of sex differences, we analyzed multiple, large-scale,
Externí odkaz:
https://doaj.org/article/659267bf36424f10b6dc38a41aa18e59
Autor:
Tomas Lagunas, Stephen P. Plassmeyer, Anthony D. Fischer, Ryan Z. Friedman, Michael A. Rieger, Din Selmanovic, Simona Sarafinovska, Yvette K. Sol, Michael J. Kasper, Stuart B. Fass, Alessandra F. Aguilar Lucero, Joon-Yong An, Stephan J. Sanders, Barak A. Cohen, Joseph D. Dougherty
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract The function of regulatory elements is highly dependent on the cellular context, and thus for understanding the function of elements associated with psychiatric diseases these would ideally be studied in neurons in a living brain. Massively
Externí odkaz:
https://doaj.org/article/1be3cfd23894463dbf386a6bfd6edefd
Publikováno v:
Biological Psychiatry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14ae3b893582d0eda33217bf01547c4a
https://doi.org/10.1016/j.biopsych.2023.02.009
https://doi.org/10.1016/j.biopsych.2023.02.009
Autor:
Joseph D. Dougherty, Natasha Marrus, Susan E. Maloney, Benjamin Yip, Sven Sandin, Tychele N. Turner, Din Selmanovic, Kristen L. Kroll, David H. Gutmann, John N. Constantino, Lauren A. Weiss
Publikováno v:
Neuron, vol 110, iss 20
Male sex is a strong risk factor for autism spectrum disorder (ASD). The leading theory for a "female protective effect" (FPE) envisions males and females have "differing thresholds" under a "liability threshold model" (DT-LTM). Specifically, this mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9584b7d63502551a4d8982e9fd2fb832
https://escholarship.org/uc/item/7048860t
https://escholarship.org/uc/item/7048860t
Genome-wide association studies have discovered blocks of common variants—likely transcriptional-regulatory—associated with major depressive disorder (MDD), though the functional subset and their biological impacts remain unknown. Likewise, why d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e86d655f64ec195b9aaa88289bf0035c
https://doi.org/10.1101/2021.11.01.466849
https://doi.org/10.1101/2021.11.01.466849
Autor:
Tomas Lagunas, Stephen P. Plassmeyer, Anthony D. Fischer, Ryan Z. Friedman, Michael A. Rieger, Din Selmanovic, Simona Sarafinovska, Alessandra F. Aguilar Lucero, Joon-Yong An, Stephan J. Sanders, Barak A. Cohen, Joseph D. Dougherty
Human genetic studies have identified a large number of disease-associated de novo variants in presumptive regulatory regions of the genome that pose a challenge for interpretation of their effects: the impact of regulatory variants is highly depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5db31e91a8bfe4e901e442c6d89dc0c
https://doi.org/10.1101/2021.05.17.444514
https://doi.org/10.1101/2021.05.17.444514
Autor:
Prakash Chinnaiyan, Din Selmanovic, Shanshan Zhang, Jill Jones, Jasmin Sponagel, Cheryl Frankfater, Joseph E. Ippolito, Joshua B. Rubin
Publikováno v:
Neuro-oncology Advances
Glioblastoma (GBM) is the most aggressive primary brain tumor in adults. GBM occurs more commonly in males but female patients survive significantly longer. Understanding the molecular mechanisms underlying this clinical sex disparity could support n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a41ce1eb2064e99ae90fc5c4f5a033
https://doi.org/10.1093/noajnl/vdab024.082
https://doi.org/10.1093/noajnl/vdab024.082
Autor:
Marissa Maltry, Christina M. Estrada, Elizabeth T. Nguyen, Matia B. Solomon, Ana Franco-Villanueva, Din Selmanovic, Rachel Morano
Publikováno v:
Hormones and Behavior. 126:104852
Stress confers risk for the development and progression of Alzheimer's disease (AD). Relative to men, women are disproportionately more likely to be diagnosed with this neurodegenerative disease. We hypothesized that sex differences in endocrine stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad3c7eedb0ec8054ad685e7654b48da3
https://doi.org/10.1016/j.yhbeh.2020.104852
https://doi.org/10.1016/j.yhbeh.2020.104852