Baloxavir Marboxil Single-dose Treatment in Influenza-infected Children

Autor: Baker, Jeffrey, Block, Stanley L., Matharu, Balpreet, Burleigh Macutkiewicz, Laura, Wildum, Steffen, Dimonaco, Sophie, Collinson, Neil, Clinch, Barry, Piedra, Pedro A.

Publikováno v: The Pediatric Infectious Disease Journal

Background: Baloxavir marboxil (baloxavir) is a novel, cap-dependent endonuclease inhibitor that has previously demonstrated efficacy in the treatment of influenza in adults and adolescents. We assessed the safety and efficacy of baloxavir in otherwi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::79be66748e98f135c03affa56baa2d32
http://europepmc.org/articles/PMC7360097

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Transaminase Levels and Hepatic Events During Tocilizumab Treatment:Pooled Analysis of Long-Term Clinical Trial Safety Data in Rheumatoid Arthritis

Autor: Genovese, Mark C., Kremer, Joel M., van Vollenhoven, Ronald F., Alten, Rieke, Scali, Juan Jose, Kelman, Ariella, Dimonaco, Sophie, Brockwell, Laura

Publikováno v: Genovese, M C, Kremer, J M, van Vollenhoven, R F, Alten, R, Scali, J J, Kelman, A, Dimonaco, S & Brockwell, L 2017, ' Transaminase Levels and Hepatic Events During Tocilizumab Treatment : Pooled Analysis of Long-Term Clinical Trial Safety Data in Rheumatoid Arthritis ', Arthritis and Rheumatology, vol. 69, no. 9, pp. 1751-1761 . https://doi.org/10.1002/art.40176
Arthritis & rheumatology (Hoboken, N.J.), 69(9), 1751-1761. John Wiley and Sons Ltd
Arthritis and Rheumatology, 69(9), 1751-1761. John Wiley and Sons Ltd

Objective: To investigate liver enzyme abnormalities and hepatic adverse events (AEs) during long-term tocilizumab treatment for rheumatoid arthritis in clinical trials. Methods: Data were pooled from patients who received intravenous tocilizumab (4,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b72d606b93d982e48d7b20b9a26d37d8
https://research.vumc.nl/en/publications/d37796c0-e85a-42b7-aa52-11cebb2d0779

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