Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Dimitry Topolnik"'
Autor:
Felix Michaud, Ruggiero Francavilla, Dimitry Topolnik, Parisa Iloun, Suhel Tamboli, Frederic Calon, Lisa Topolnik
Publikováno v:
eLife, Vol 13 (2024)
Alzheimer’s disease (AD) leads to progressive memory decline, and alterations in hippocampal function are among the earliest pathological features observed in human and animal studies. GABAergic interneurons (INs) within the hippocampus coordinate
Externí odkaz:
https://doaj.org/article/d9e5304ffee34b25896f700dee2e3aff
Autor:
Suhel Tamboli, Dimitry Topolnik, Risna Radhakrishnan, Daphnée Veilleux-Lemieux, Lisa Topolnik
Publikováno v:
STAR Protocols, Vol 5, Iss 4, Pp 103407- (2024)
Summary: Fiber photometry technique allows investigation of in vivo neural activity during behavior allowing understanding of brain-behavior relationship. Here, we provide a protocol for synchronized wireless fiber photometry and video recordings in
Externí odkaz:
https://doaj.org/article/8bb942071f2545c58cce50f4a7274a71
Autor:
Suhel Tamboli, Sanjay Singh, Dimitry Topolnik, Mohamed El Amine Barkat, Risna Radhakrishnan, Alexandre Guet-McCreight, Lisa Topolnik
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114115- (2024)
Summary: In the CA1 hippocampus, vasoactive intestinal polypeptide-expressing interneurons (VIP-INs) play a prominent role in disinhibitory circuit motifs. However, the specific behavioral conditions that lead to circuit disinhibition remain uncertai
Externí odkaz:
https://doaj.org/article/0014c5e195b04b84a385ab3d1dcc7df4
Autor:
Sona Amalyan, Suhel Tamboli, Ivan Lazarevich, Dimitry Topolnik, Leandra Harriet Bouman, Lisa Topolnik
Publikováno v:
Cell Reports, Vol 40, Iss 1, Pp 111043- (2022)
Summary: Information and action coding by cortical circuits relies on a balanced dialogue between excitation and inhibition. Circuit hyperexcitability is considered a potential pathophysiological mechanism in various brain disorders, but the underlyi
Externí odkaz:
https://doaj.org/article/41eb4a2f0bae451b88078ce23b977c81
Autor:
Ruggiero Francavilla, Alexandre Guet-McCreight, Sona Amalyan, Chin Wai Hui, Dimitry Topolnik, Félix Michaud, Beatrice Marino, Marie-Ève Tremblay, Frances K. Skinner, Lisa Topolnik
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Learning and memory deficits are hallmarks of the aging brain, with cortical neuronal circuits representing the main target in cognitive deterioration. While GABAergic inhibitory and disinhibitory circuits are critical in supporting cognitive process
Externí odkaz:
https://doaj.org/article/64575d5eb46b43aeb170a4dc28f9bbe1