Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Dimitris Skokos"'
Autor:
Bei Wang, Jacquelynn Golubov, Erin M. Oswald, Patrick Poon, Qiaozhi Wei, Clarissa Lett, Fadi Shehadeh, Matthew Kaczynski, Lewis Oscar Felix, Biswajit Mishra, Evangelia K. Mylona, Matthew F. Wipperman, Erica Chio, Sara C. Hamon, Andrea T. Hooper, Selin Somersan-Karakaya, Bret J. Musser, Christopher D. Petro, Jennifer D. Hamilton, Matthew A. Sleeman, George D. Kalliolias, Eleftherios Mylonakis, Dimitris Skokos
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105334- (2024)
Summary: Background: Passive administration of SARS-CoV-2 neutralizing monoclonal antibodies (mAbs), such as CAS + IMD (Casirivimab + Imdevimab) antibody cocktail demonstrated beneficial effects on clinical outcomes in hospitalized patients with COVI
Externí odkaz:
https://doaj.org/article/2b0af8e604764c0bbe87f262c39423c8
Autor:
Allen Y. Leary, Darius Scott, Namita T. Gupta, Janelle C. Waite, Dimitris Skokos, Gurinder S. Atwal, Peter G. Hawkins
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract T Cell Receptor (TCR) antigen binding underlies a key mechanism of the adaptive immune response yet the vast diversity of TCRs and the complexity of protein interactions limits our ability to build useful low dimensional representations of T
Externí odkaz:
https://doaj.org/article/1820b41f4a474b529dd9e7094a5d49f9
Autor:
Israel Lowy, Roman Groisberg, Nehal Lakhani, Melissa Mathias, Siyu Li, Melissa Johnson, Frank Seebach, Matthew Fury, Hyunsil Han, Kerry Casey, Dimitris Skokos
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/4b4e264a11ce43b6979c1d79a9b3d579
Autor:
Xuan Ye, Janelle C. Waite, Ankur Dhanik, Namita Gupta, Maggie Zhong, Christina Adler, Evangelia Malahias, Min Ni, Yi Wei, Cagan Gurer, Wen Zhang, Lynn E. Macdonald, Andrew J. Murphy, Matthew A. Sleeman, Dimitris Skokos
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Clinical observations suggest that responses to cancer immunotherapy are correlated with intra-tumoral T cell receptor (TCR) clonality, tumor mutation burden (TMB) and host HLA genotype, highlighting the importance of host T cell recognition of tumor
Externí odkaz:
https://doaj.org/article/e5e01689ac6541e6844a8430c0033c6b
Autor:
Fabienne Billiard, Sevasti Karaliota, Bei Wang, Dimitrios Stellas, Ioannis Serafimidis, Antigoni Manousopoulou, Yiassemi Koutmani, Elpiniki Ninou, Jacquelynn Golubov, Amanda DaNave, Panagiotis Tsakanikas, Yurong Xin, Wen Zhang, Matthew Sleeman, George D. Yancopoulos, Andrew J. Murphy, Spiros D. Garbis, Katia Karalis, Dimitris Skokos
Publikováno v:
Cell Reports, Vol 22, Iss 4, Pp 895-904 (2018)
Although Notch signaling has been proposed as a therapeutic target for type-2 diabetes, liver steatosis, and atherosclerosis, its direct effect on pancreatic islets remains unknown. Here, we demonstrated a function of Dll4-Notch signaling inhibition
Externí odkaz:
https://doaj.org/article/903bd16654ce4a97829d73e1cec13363
Autor:
Yu Bai, David Wang, Wentian Li, Ying Huang, Xuan Ye, Janelle Waite, Thomas Barry, Kurt H Edelmann, Natasha Levenkova, Chunguang Guo, Dimitris Skokos, Yi Wei, Lynn E Macdonald, Wen Fury
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207020 (2018)
Profiling T cell receptor (TCR) repertoire via short read transcriptome sequencing (RNA-Seq) has a unique advantage of probing simultaneously TCRs and the genome-wide RNA expression of other genes. However, compared to targeted amplicon approaches, t
Externí odkaz:
https://doaj.org/article/f8307da7b8254a5db4491773e8d42ee4
Publikováno v:
International Journal of Inflammation, Vol 2012 (2012)
Externí odkaz:
https://doaj.org/article/fa5d7aec64a54185aca584c72be133d1
Autor:
Janelle C. Waite, Dimitris Skokos
Publikováno v:
International Journal of Inflammation, Vol 2012 (2012)
The proinflammatory activity of T helper 17 (Th17) cells can be beneficial to the host during infection. However, uncontrolled or inappropriate Th17 activation has been linked to several autoimmune and autoinflammatory pathologies. Indeed, preclinica
Externí odkaz:
https://doaj.org/article/a2c8f0eb65ca449e8da0d40958190824
Autor:
April S Chan, Kristian K Jensen, Dimitris Skokos, Stephen Doty, Hannah K Lederman, Rosandra N Kaplan, Shahin Rafii, Stefano Rivella, David Lyden
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7955 (2009)
The bone-bone marrow interface is an area of the bone marrow microenvironment in which both bone remodeling cells, osteoblasts and osteoclasts, and hematopoietic cells are anatomically juxtaposed. The close proximity of these cells naturally suggests
Externí odkaz:
https://doaj.org/article/e4debfe3414c41deb8874fd33d878855
Autor:
Gavin Thurston, Andrew Murphy, Israel Lowy, William Olson, Ella Ioffe, Douglas MacDonald, Markus Mohrs, Jon Popke, Joel Kantrowitz, Dimitris Skokos, Tammy Huang, Joel Martin, William Poueymirou, Ashique Rafique, Elena Garnova, Amanda D’Orvilliers, Qi Wu, Amy Woodruff, Omaira Allbritton, Matt Liu, Seongwon Hong, Venus Lai, Terra Potocky, Janelle Waite, Aynur Hermann, Elena Burova
Measuring binding kinetics of human and mouse PD-1/PD-L1 interactions using surface plasmon resonance.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abdc3e2aa5dabdab092517874e623442
https://doi.org/10.1158/1535-7163.22505004
https://doi.org/10.1158/1535-7163.22505004
