Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Dimitris Missirlis"'
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract The precise mechanisms through which insoluble, cell-adhesive ligands induce and regulate directional cell migration remain obscure. We recently demonstrated that elevated surface density of physically adsorbed plasma fibronectin (FN) promot
Externí odkaz:
https://doaj.org/article/f05ac0fbbf9a498f9e9f5b297e6e308e
Autor:
Dimitris Missirlis
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96548 (2014)
Substrate mechanical properties have emerged as potent determinants of cell functions and fate. We here tested the hypothesis that different forms of endocytosis are regulated by the elasticity of the synthetic hydrogels cells are cultured on. Toward
Externí odkaz:
https://doaj.org/article/63391a0a841a4fe6a62b715e1a64f79b
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54611 (2013)
BACKGROUND: Peptide amphiphiles (PAs) are a class of amphiphilic molecules able to self-assemble into nanomaterials that have shown efficient in vivo targeted delivery. Understanding the interactions of PAs with cells and the mechanisms of their inte
Externí odkaz:
https://doaj.org/article/1b8fea25077149d7952be6b35a24d6c6
Publikováno v:
ACS Applied Materials & Interfaces
ACS Applied Materials and Interfaces
ACS Applied Materials and Interfaces
We here present a micropatterning strategy to introduce small molecules and ligands on patterns of arbitrary shapes on the surface of poly(acrylamide)-based hydrogels. The main advantages of the presented approach are the ease of use, the lack of nee
Autor:
Carolina Diaz, Dimitris Missirlis
Publikováno v:
Advanced Healthcare Materials
Amyloid fibrils may serve as building blocks for the preparation of novel hydrogel materials from abundant, low cost and biocompatible polypeptides. Here, we present the formation of physically cross-linked, self-healing hydrogels based on bovine ser
Publikováno v:
Biomaterials
The established link between deregulated tissue mechanics and various pathological states calls for the elucidation of the processes through which cells interrogate and interpret the mechanical properties of their microenvironment. In this work, we d
Autor:
Dimitris Missirlis, Christine Lansche, Marilou Tétard, Anil K. Dasanna, Benjamin Fröhlich, Benoit Gamain, Ulrich S. Schwarz, Cecilia P. Sanchez, Katharina A. Quadt, Bernd Buchholz, Motomu Tanaka, Michael Lanzer
Publikováno v:
Communications Biology, Vol 1, Iss 1, Pp 1-14 (2018)
Communications Biology
Communications Biology, Nature Publishing Group, 2018, 1 (1), ⟨10.1038/s42003-018-0223-3⟩
Communications Biology
Communications Biology, Nature Publishing Group, 2018, 1 (1), ⟨10.1038/s42003-018-0223-3⟩
Sickle cell trait, a common hereditary blood disorder, protects carriers from severe disease in infections with the human malaria parasite Plasmodium falciparum. Protection is associated with a reduced capacity of parasitized erythrocytes to cytoadhe
Publikováno v:
Biophys J
The mechanics of fibronectin-rich extracellular matrix regulate cell physiology in a number of diseases, prompting efforts to elucidate cell mechanosensing mechanisms at the molecular and cellular scale. Here, the use of fibronectin-functionalized si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a8324efa3947853164d44459428d04
https://doi.org/10.1101/2020.05.15.098046
https://doi.org/10.1101/2020.05.15.098046
Autor:
Carolina, Diaz, Stefanie, Neubauer, Florian, Rechenmacher, Horst, Kessler, Dimitris, Missirlis
Publikováno v:
Journal of cell science. 133(1)
The major fibronectin (FN)-binding α
Publikováno v:
ACS Nano
The extracellular environment is a complex medium in which cells secrete and consume metabolites. Molecular gradients are thereby created near cells, triggering various biological and physiological responses. However, investigating these molecular gr