Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Dimitris Konstantopoulos"'
Autor:
Fani Roumelioti, Christos Tzaferis, Dimitris Konstantopoulos, Dimitra Papadopoulou, Alejandro Prados, Maria Sakkou, Anastasios Liakos, Panagiotis Chouvardas, Theodore Meletakos, Yiannis Pandis, Niki Karagianni, Maria C Denis, Maria Fousteri, Maria Armaka, George Kollias
Publikováno v:
eLife, Vol 13 (2024)
miRNAs constitute fine-tuners of gene expression and are implicated in a variety of diseases spanning from inflammation to cancer. miRNA expression is deregulated in rheumatoid arthritis (RA); however, their specific role in key arthritogenic cells s
Externí odkaz:
https://doaj.org/article/e5d50d4d00c3408c8809b26c70ef81cd
Autor:
Prodromos Sidiropoulos, George Bertsias, Despoina Kosmara, Chrysoula Stathopoulou, Konstantina Pambouka, Sofia Papanikolaou, Dimitra Nikoleri, Dimitris Konstantopoulos, Maria Semitekolou
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 1 (2024)
Externí odkaz:
https://doaj.org/article/2311f7ff16aa49cfbdc3b2cd86a89d0f
Autor:
Prodromos Sidiropoulos, George Bertsias, Despoina Kosmara, Aggelos Banos, Dimitrios Boumpas, Chrysoula Stathopoulou, Sofia Papanikolaou, Dimitris Konstantopoulos, Giannis Vatsellas
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 1 (2024)
Externí odkaz:
https://doaj.org/article/698e815a91aa4d4dad4f91291d4030d2
Autor:
Christos Tzaferis, Evangelos Karatzas, Fotis A. Baltoumas, Georgios A. Pavlopoulos, George Kollias, Dimitris Konstantopoulos
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 5382-5393 (2023)
Analysis and interpretation of high-throughput transcriptional and chromatin accessibility data at single-cell (sc) resolution are still open challenges in the biomedical field. The existence of countless bioinformatics tools, for the different analy
Externí odkaz:
https://doaj.org/article/be96fafcfd7b4b45b40395e5e4eea19f
Autor:
Smaragda Fanourgakis, Anna-Chloe Synacheri, Matthieu D. Lavigne, Dimitris Konstantopoulos, Maria Fousteri
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 614-629 (2023)
The timing and location of writing and erasing of histone modifications determine gene expression programs and are tightly controlled processes. One such modification is the monoubiquitination of histone H2B (H2Bub), whose precise level during transc
Externí odkaz:
https://doaj.org/article/5dc450684361456cbf8abbd316841ff8
Autor:
Marietta Armaka, Dimitris Konstantopoulos, Christos Tzaferis, Matthieu D. Lavigne, Maria Sakkou, Anastasios Liakos, Petros P. Sfikakis, Meletios A. Dimopoulos, Maria Fousteri, George Kollias
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-25 (2022)
Abstract Background Synovial fibroblasts (SFs) are specialized cells of the synovium that provide nutrients and lubricants for the proper function of diarthrodial joints. Recent evidence appreciates the contribution of SF heterogeneity in arthritic p
Externí odkaz:
https://doaj.org/article/e3d563008788498999bef7a57c3f48e0
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
A transcription-driven cellular response is activated upon UV stress. Here the authors reveal mechanistic insights into the regulatory process affecting transcription and chromatin dynamics, showing how maintaining Pol II firing safeguards the integr
Externí odkaz:
https://doaj.org/article/de13ff9326e049b98166cdb29b54b7f9
Autor:
Matthieu D. Lavigne, Dimitris Konstantopoulos, Katerina Z. Ntakou-Zamplara, Anastasios Liakos, Maria Fousteri
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Precise orchestration of gene expression regulation upon DNA damage is essential for genome integrity. Here the authors identify a novel widespread stress-triggered defence mechanism that promotes rapid transcription-driven genomic surveillance thus
Externí odkaz:
https://doaj.org/article/43adcd781e174d94a8fcc1b10dd0a0dd
Autor:
Nikiana Simigdala, Anna Chalari, Aimilia D. Sklirou, Evangelia Chavdoula, George Papafotiou, Pelagia Melissa, Aimilia Kafalidou, Nikolaos Paschalidis, Ioannis S. Pateras, Emmanouil Athanasiadis, Dimitris Konstantopoulos, Ioannis P. Trougakos, Apostolos Klinakis
Publikováno v:
Cellular and Molecular Life Sciences. 80
Deep sequencing of human tumours has uncovered a previously unappreciated role for epigenetic regulators in tumorigenesis. H3K4 methyltransferase KMT2C/MLL3 is mutated in several solid malignancies, including more than 10% of breast tumours. To study
Autor:
Christos Tzaferis, Evangelos Karatzas, Fotis A. Baltoumas, Georgios A. Pavlopoulos, George Kollias, Dimitris Konstantopoulos
Analysis and interpretation of high-throughput transcriptional and chromatin accessibility data at single cell resolution are still open challenges in the biomedical field. In this article, we present SCALA, a bioinformatics tool for analysis and vis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::085ec79fe7d2fd51843f3b09f8020971
https://doi.org/10.1101/2022.11.24.517826
https://doi.org/10.1101/2022.11.24.517826