Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Dimitrios Voukantsis"'
Autor:
Pahala Gedara Jayathilake, Pedro Victori, Clara E Pavillet, Chang Heon Lee, Dimitrios Voukantsis, Ana Miar, Anjali Arora, Adrian L Harris, Karl J Morten, Francesca M Buffa
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 3, p e1011944 (2024)
Deregulated metabolism is one of the hallmarks of cancer. It is well-known that tumour cells tend to metabolize glucose via glycolysis even when oxygen is available and mitochondrial respiration is functional. However, the lower energy efficiency of
Externí odkaz:
https://doaj.org/article/0eb01951447743aaa95598c797984cf8
Autor:
Christos E. Zois, Anne M. Hendriks, Syed Haider, Elisabete Pires, Esther Bridges, Dimitra Kalamida, Dimitrios Voukantsis, B. Christoffer Lagerholm, Rudolf S. N. Fehrmann, Wilfred F. A. den Dunnen, Andrei I. Tarasov, Otto Baba, John Morris, Francesca M. Buffa, James S. O. McCullagh, Mathilde Jalving, Adrian L. Harris
Publikováno v:
Cell Death and Disease, Vol 13, Iss 6, Pp 1-15 (2022)
Abstract Channelling of glucose via glycogen, known as the glycogen shunt, may play an important role in the metabolism of brain tumours, especially in hypoxic conditions. We aimed to dissect the role of glycogen degradation in glioblastoma (GBM) res
Externí odkaz:
https://doaj.org/article/b1ef617fb3104ffda4ec574e955e7b3f
Autor:
Andrés Noé, Mehreen S. Datoo, Amy Flaxman, Mohammad Ali Husainy, Daniel Jenkin, Duncan Bellamy, Rebecca A. Makinson, Richard Morter, Fernando Ramos Lopez, Jonathan Sheridan, Dimitrios Voukantsis, Naveen Prasad, Adrian V. S. Hill, Katie J. Ewer, Alexandra J. Spencer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Protection from liver-stage malaria requires high numbers of CD8+ T cells to find and kill Plasmodium-infected cells. A new malaria vaccine strategy, prime-target vaccination, involves sequential viral-vectored vaccination by intramuscular and intrav
Externí odkaz:
https://doaj.org/article/54935d5124fa4127948dd2701b4b673f
Autor:
Jakob R Kaeppler, Jianzhou Chen, Mario Buono, Jenny Vermeer, Pavitra Kannan, Wei‐Chen Cheng, Dimitrios Voukantsis, James M Thompson, Mark A Hill, Danny Allen, Ana Gomes, Veerle Kersemans, Paul Kinchesh, Sean Smart, Francesca Buffa, Claus Nerlov, Ruth J Muschel, Bostjan Markelc
The effect of radiation therapy on tumor vasculature has long been a subject of debate. Increased oxygenation and perfusion have been documented during radiation therapy. Conversely, apoptosis of endothelial cells in irradiated tumors has been propos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc2e6aacda242853e980d0c79943b9e
https://ora.ox.ac.uk/objects/uuid:05bc5075-f9bf-4480-aa4a-b9f30439bd33
https://ora.ox.ac.uk/objects/uuid:05bc5075-f9bf-4480-aa4a-b9f30439bd33
microC is a multiscale virtual microenvironment for perturbation biology. It enables experiments that link genotype to phenotype taking into account the surrounding microenvironment. microC has a modular architecture that enables a wide variety of ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfccb7aa1062eaf231e90b029ad6fc87
https://doi.org/10.17504/protocols.io.wtjfekn
https://doi.org/10.17504/protocols.io.wtjfekn
Publikováno v:
GigaScience
A cell’s phenotype is the set of observable characteristics resulting from the interaction of the genotype with the surrounding environment, determining cell behaviour. Deciphering genotype-phenotype relationships has been crucial to understand nor
microC is a multiscale virtual microenvironment for perturbation biology. It enables experiments that link genotype to phenotype taking into account the surrounding microenvironment. microC has a modular architecture that enables a wide variety of ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0c4a2c010b6642c21849862e7480eab
https://doi.org/10.17504/protocols.io.vxue7nw
https://doi.org/10.17504/protocols.io.vxue7nw