Zobrazeno 1 - 10
of 273
pro vyhledávání: '"Dimitrios Vlachakis"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8256 (2024)
Exosomes, natural nanovesicles that contain a cargo of biologically active molecules such as lipids, proteins, and nucleic acids, are released from cells to the extracellular environment. They then act as autocrine, paracrine, or endocrine mediators
Externí odkaz:
https://doaj.org/article/2eb9bc42f31e455293a2089d913c6f82
Autor:
Margaritis Tsifintaris, Michail Sitmalidis, Maria Tokamani, Christina Anastasiadi, Maria Georganta, Ilias Tsochantaridis, Dimitrios Vlachakis, Panagiotis Tsikouras, Nikolaos Nikolettos, George P. Chrousos, Raphael Sandaltzopoulos, Antonis Giannakakis
Publikováno v:
Nutrients, Vol 16, Iss 14, p 2175 (2024)
Milk is a biological fluid with a dynamic composition of micronutrients and bioactive molecules that serves as a vital nutrient source for infants. Milk composition is affected by multiple factors, including genetics, geographical location, environme
Externí odkaz:
https://doaj.org/article/5164d7d9710547fb9ab44c3269210206
Autor:
Louis Papageorgiou, Lefteria Papa, Eleni Papakonstantinou, Antonia Mataragka, Konstantina Dragoumani, Dimitrios Chaniotis, Apostolos Beloukas, Costas Iliopoulos, Erik Bongcam-Rudloff, George P. Chrousos, Sofia Kossida, Elias Eliopoulos, Dimitrios Vlachakis
Publikováno v:
Genes, Vol 15, Iss 5, p 529 (2024)
The evolutionary conserved Notch signaling pathway functions as a mediator of direct cell–cell communication between neighboring cells during development. Notch plays a crucial role in various fundamental biological processes in a wide range of tis
Externí odkaz:
https://doaj.org/article/40671169631b48e2ac8adbd342decc5a
Autor:
Dimitra Siori, Dimitrios Vlachakis, Periklis Makrythanasis, Joanne Traeger-Synodinos, Danai Veltra, Afrodite Kampouraki, George P. Chrousos
Publikováno v:
Genes, Vol 15, Iss 5, p 525 (2024)
Infantile onset transient hypomyelination (IOTH) is a rare form of leukodystrophy that is associated with transient motor impairment and delayed central nervous system myelination. Here, we report a case of a new mutation in the transmembrane protein
Externí odkaz:
https://doaj.org/article/d9f1790fb03d444297ee8e43965657db
Autor:
Dimitrios Vlachakis, Konstantinos Tsilafakis, Ioanna Kostavasili, Sophia Kossida, Manolis Mavroidis
Publikováno v:
Cells, Vol 13, Iss 7, p 603 (2024)
Understanding the structure and function of intermediate filaments (IFs) is necessary in order to explain why more than 70 related IF genes have evolved in vertebrates while maintaining such dramatically tissue-specific expression. Desmin is a member
Externí odkaz:
https://doaj.org/article/8f242e5a039f400d8b5284af5bb1da50
Autor:
Rafailia A. A. Beta, Athanasios Kyritsis, Veroniki Douka, Eirini Papanastasi, Marianna Rizouli, Demetres D. Leonidas, Dimitrios Vlachakis, Nikolaos A. A. Balatsos
Publikováno v:
FEBS Open Bio, Vol 12, Iss 5, Pp 1036-1049 (2022)
The 24‐h molecular clock is based on the stability of rhythmically expressed transcripts. The shortening of the poly(A) tail of mRNAs is often the first and rate‐limiting step that determines the lifespan of a mRNA and is catalyzed by deadenylase
Externí odkaz:
https://doaj.org/article/96c2b72e4e1b4f3cb35595297c948d75
Publikováno v:
Genes, Vol 14, Iss 6, p 1246 (2023)
Ankyloblepharon-ectodermal defects-cleft lip/palate (AEC) syndrome is a rare autosomal dominant disorder. AEC is caused by mutations in the TP63 gene that encodes the tumor suppressor p63 protein, itself involved in the regulation of epidermal prolif
Externí odkaz:
https://doaj.org/article/576a537f37fc488d9a590064bbe6ef82
Autor:
Vassos Neocleous, Pavlos Fanis, Meropi Toumba, Barbara Gorka, Ioanna Kousiappa, George A. Tanteles, Michalis Iasonides, Nicolas C. Nicolaides, Yiolanda P. Christou, Kyriaki Michailidou, Stella Nicolaou, Savvas S. Papacostas, Athanasios Christoforidis, Andreas Kyriakou, Dimitrios Vlachakis, Nicos Skordis, Leonidas A. Phylactou
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
BackgroundCentral precocious puberty (CPP) due to premature activation of GnRH secretion results in early epiphyseal fusion and to a significant compromise in the achieved final adult height. Currently, few genetic determinants of children with CPP h
Externí odkaz:
https://doaj.org/article/6419e03e08384921a33f330e4e460fac
Integrated Deadenylase Genetic Association Network and Transcriptome Analysis in Thoracic Carcinomas
Autor:
Athanasios Kyritsis, Eirini Papanastasi, Ioanna Kokkori, Panagiotis Maragozidis, Demetra S. M. Chatzileontiadou, Paschalina Pallaki, Maria Labrou, Sotirios G. Zarogiannis, George P. Chrousos, Dimitrios Vlachakis, Konstantinos I. Gourgoulianis, Nikolaos A. A. Balatsos
Publikováno v:
Molecules, Vol 27, Iss 10, p 3102 (2022)
The poly(A) tail at the 3′ end of mRNAs determines their stability, translational efficiency, and fate. The shortening of the poly(A) tail, and its efficient removal, triggers the degradation of mRNAs, thus, regulating gene expression. The process
Externí odkaz:
https://doaj.org/article/e965df14203a4a619fcc0f2090e61b89
Autor:
Isabel Moreno-Indias, Leo Lahti, Miroslava Nedyalkova, Ilze Elbere, Gennady Roshchupkin, Muhamed Adilovic, Onder Aydemir, Burcu Bakir-Gungor, Enrique Carrillo-de Santa Pau, Domenica D’Elia, Mahesh S. Desai, Laurent Falquet, Aycan Gundogdu, Karel Hron, Thomas Klammsteiner, Marta B. Lopes, Laura Judith Marcos-Zambrano, Cláudia Marques, Michael Mason, Patrick May, Lejla Pašić, Gianvito Pio, Sándor Pongor, Vasilis J. Promponas, Piotr Przymus, Julio Saez-Rodriguez, Alexia Sampri, Rajesh Shigdel, Blaz Stres, Ramona Suharoschi, Jaak Truu, Ciprian-Octavian Truică, Baiba Vilne, Dimitrios Vlachakis, Ercument Yilmaz, Georg Zeller, Aldert L. Zomer, David Gómez-Cabrero, Marcus J. Claesson
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The human microbiome has emerged as a central research topic in human biology and biomedicine. Current microbiome studies generate high-throughput omics data across different body sites, populations, and life stages. Many of the challenges in microbi
Externí odkaz:
https://doaj.org/article/58ddf268165e41df95208c7ec045cc9d