Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Dimitrios N. Vatakis"'
Autor:
Rachel S. Resop, Bradley Salvatore, Shawn J. Kim, Brent R. Gordon, Bianca Blom, Dimitrios N. Vatakis, Christel H. Uittenbogaart
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 13865 (2023)
Regeneration of functional naïve T lymphocytes following the onset of human immunodeficiency virus (HIV) infection remains a crucial issue for people living with HIV (PLWH), even when adhering to antiretroviral therapy (ART). Thus far, reports on th
Externí odkaz:
https://doaj.org/article/bb971304dda143f1b6f29cedd66bbaa9
Autor:
Rachel S. Resop, Bradley Salvatore, Shawn J. Kim, Brent Gordon, Bianca Blom, Dimitrios N. Vatakis, Christel H. Uittenbogaart
Regeneration of functional naïve T lymphocytes following the onset of infection remains a crucial issue for HIV + individuals, even while adhering to Antiretroviral Therapy (ART). Thus far, reports on the impact of HIV-1 infection on the entry of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8e70376b812a5caaf04db3cb337869e
https://doi.org/10.21203/rs.3.rs-2124035/v1
https://doi.org/10.21203/rs.3.rs-2124035/v1
Autor:
Bryan P Burke, Bernard R Levin, Jane Zhang, Anna Sahakyan, Joshua Boyer, Maria V Carroll, Joanna Camba Colón, Naomi Keech, Valerie Rezek, Gregory Bristol, Erica Eggers, Ruth Cortado, Maureen P Boyd, Helen Impey, Saki Shimizu, Emily L Lowe, Gene-Errol E Ringpis, Sohn G Kim, Dimitrios N Vatakis, Louis R Breton, Jeffrey S Bartlett, Irvin S Y Chen, Scott G Kitchen, Dong Sung An, Geoff P Symonds
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 4, Iss C (2015)
We described earlier a dual-combination anti-HIV type 1 (HIV-1) lentiviral vector (LVsh5/C46) that downregulates CCR5 expression of transduced cells via RNAi and inhibits HIV-1 fusion via cell surface expression of cell membrane-anchored C46 antivira
Externí odkaz:
https://doaj.org/article/3e5b33d836f143b2a0a873b4e9851286
Publikováno v:
Global Virology II-HIV and NeuroAIDS ISBN: 9781493972883
Mice have been used in basic science research over decades as small in vivo models to study human immunity and disease. Despite their shortcomings, they have yielded valuable information that lead to the development of effective therapies against can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d25ab0a0b5136da47e5fe28539774cf
https://doi.org/10.1007/978-1-4939-7290-6_22
https://doi.org/10.1007/978-1-4939-7290-6_22
Publikováno v:
Immunologic Research. 48:110-121
The ability of HIV to infect quiescent CD4+ T cells has been a topic of intense debate. While early studies suggested that the virus could not infect this particular T cell subset, subsequent studies using more sensitive protocols demonstrated that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::099998608d04262445f432244945abc3
https://doi.org/10.1007/s12026-010-8171-0
https://doi.org/10.1007/s12026-010-8171-0
Publikováno v:
Journal of Virology. 83:3374-3378
The activation state of CD4 + T cells plays a crucial role in the establishment of a productive human immunodeficiency virus infection. Here, we show that T cells stimulated for 1 day demonstrated delayed kinetics of viral reverse transcription and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184d7eeb8a2f0b18a73fc049cfc369cf
https://doi.org/10.1128/jvi.02161-08
https://doi.org/10.1128/jvi.02161-08
Autor:
Matthew D. Marsden, Jerome A. Zack, Dimitrios N. Vatakis, Bryan P. Burke, Gregory Bristol, Helen Brown
Publikováno v:
Journal of Virology. 81:7424-7434
Quiescent T lymphocytes containing latent human immunodeficiency virus (HIV) provide a long-lived viral reservoir. This reservoir may be the source of active infection that is reinitiated following the cessation of antiretroviral therapy. Therefore,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec0a816882aa25d9df348bde68c5671a
https://doi.org/10.1128/jvi.02838-06
https://doi.org/10.1128/jvi.02838-06
Autor:
Dimitrios N. Vatakis, Dhaval Dixit, Brandon H. Schwartz, Christopher C. Nixon, Jerome A. Zack
Publikováno v:
Scientific Reports. 5
Prenatal exposure to cocaine is a significant source of fetal and neonatal developmental defects. While cocaine associated neurological and cardiac pathologies are well-documented, it is apparent that cocaine use has far more diverse physiological ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38779a57fecc73e6534eae5301dbf993
https://doi.org/10.1038/srep09798
https://doi.org/10.1038/srep09798
Autor:
Dimitrios N. Vatakis, Dhaval Dixit, Cindy Youn, Sohn G. Kim, Jerome A. Zack, Emily L. Lowe, Irene J. Kim, James B. Jung, Robert Rovner
Publikováno v:
Scientific Reports
Cocaine abuse has been shown to have broad-ranging effects on human immunity. With regards to HIV infection, in vitro studies have shown that cocaine enhances infection of stimulated lymphocytes. Moreover, cohort studies in the pre- and post-HAART er
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a853e3015fdaa7ec793404cbe36163
Autor:
Jerome A. Zack, Melissa N. McCracken, Owen N. Witte, Jami McLaughlin, Dimitrios N. Vatakis, Dhaval Dixit
Publikováno v:
The Journal of clinical investigation, vol 125, iss 5
McCracken, MN; Vatakis, DN; Dixit, D; McLaughlin, J; Zack, JA; & Witte, ON. (2015). Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging. JOURNAL OF CLINICAL INVESTIGATION, 125(5), 1815-1826. doi: 10.1172/JCI77326. UCLA: Retrieved from: http://www.escholarship.org/uc/item/1d24g4dt
McCracken, MN; Vatakis, DN; Dixit, D; McLaughlin, J; Zack, JA; & Witte, ON. (2015). Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging. JOURNAL OF CLINICAL INVESTIGATION, 125(5), 1815-1826. doi: 10.1172/JCI77326. UCLA: Retrieved from: http://www.escholarship.org/uc/item/1d24g4dt
Adoptive transfer of tumor-reactive T cells can successfully reduce tumor burden; however, in rare cases, lethal on-target/off-tumor effects have been reported. A noninvasive method to track engineered cells with high sensitivity and resolution would
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2206750b759003e3164b59fad576d5e2
https://escholarship.org/uc/item/1d24g4dt
https://escholarship.org/uc/item/1d24g4dt