Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Dimitrios Mantzilas"'
Autor:
Julian Grigg, Duncan Hiscock, Bard Indrevoll, Lone Omtvedt, Matthias Glaser, Dimitrios Mantzilas, Sajinder K. Luthra, Shales Jonathan Robert, Peter Iveson
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 62:925-932
An 18 F-labelled human epidermal growth factor receptor (HER2) receptor binding radiotracer is a potential tool to non-invasively identify HER2 positive tumour lesions in subjects with recurrent metastatic breast cancer. Having explored the manual ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92d79f024a8ebb7ea553dd2e7a3ed620
https://doi.org/10.1002/jlcr.3789
https://doi.org/10.1002/jlcr.3789
Autor:
Peter B, Iveson, Matthias, Glaser, Bard, Indrevoll, Jonathan, Shales, Dimitrios, Mantzilas, Lone, Omtvedt, Sajinder K, Luthra, Duncan, Hiscock, Julian, Grigg
Publikováno v:
Journal of labelled compoundsradiopharmaceuticalsREFERENCES. 62(14)
An
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6430a88012f79d95fad9da7a49cb2465
https://pubmed.ncbi.nlm.nih.gov/31339589
https://pubmed.ncbi.nlm.nih.gov/31339589
Autor:
Ella Hirani, Bo Shan, Erik Årstad, Imtiaz Khan, Edward G. Robins, Harry John Wadsworth, Wai-Fung Chau, Sajinder K. Luthra, Joanna Passmore, Yongjun Zhao, Veronique Morisson-Iveson, Sarah Walton, William Trigg, Paul A. Jones, Michelle Avory, Dennis O'shea, Clare Durrant, Rabia Ahmad, Dimitrios Mantzilas
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:2368-2372
A series of novel TSPO ligands based on the tetracyclic class of translocator protein (TSPO) ligands first described by Okubo et al. was synthesised and evaluated as potential positron emitting tomography (PET) ligands for imaging TPSO in vivo. Fluor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394b1e289a06fbfe4bc81df52858121c
https://doi.org/10.1016/j.bmcl.2013.02.057
https://doi.org/10.1016/j.bmcl.2013.02.057
Autor:
Wai-Fung Chau, Dimitrios Mantzilas, Naghmeh Fouladi, Mikkel Thaning, Paul A. Jones, William Trigg, Veronique Morisson-Iveson, Ingvil Gausemel, Clare Durrant, Imtiaz Khan, Andrew Black, Joanna Passmore, Michelle Avory, Dennis O'shea, Harry John Wadsworth, Amanda Ewan, Duncan Wynn
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:1308-1313
A series of tricyclic compounds have been synthesised and evaluated in vitro for affinity against Translocator protein 18 kDa (TSPO) and for preferred imaging properties. The most promising of the compounds were radiolabelled and evaluated in vivo to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9f7aae2c6ef9e829fccfa42f32630ad
https://doi.org/10.1016/j.bmcl.2011.12.084
https://doi.org/10.1016/j.bmcl.2011.12.084
Publikováno v:
Journal of Molecular Biology. 341:1215-1226
The stability of tetrameric malate dehydrogenase from the green phototrophic bacterium Chloroflexus aurantiacus (CaMDH) is at least in part determined by electrostatic interactions at the dimer-dimer interface. Since previous studies had indicated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbfca2ba6848bd5b92355e913f661646
https://doi.org/10.1016/j.jmb.2004.06.079
https://doi.org/10.1016/j.jmb.2004.06.079
Publikováno v:
Journal of Molecular Biology. 334:811-821
Malate dehydrogenase (MDH) from the moderately thermophilic bacterium Chloroflexus aurantiacus (CaMDH) is a tetrameric enzyme, while MDHs from mesophilic organisms usually are dimers. To investigate the potential contribution of the extra dimer-dimer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1194b5de9a31909b53070b5d5f16c5c
https://doi.org/10.1016/j.jmb.2003.10.006
https://doi.org/10.1016/j.jmb.2003.10.006
Publikováno v:
FEBS Letters. 553:423-426
Malate dehydrogenase (MDH) from the moderately thermophilic bacterium Chloroflexus aurantiacus (CaMDH) is a tetrameric enzyme, while MDHs from mesophilic bacteria usually are dimers. Using site-directed mutagenesis, we show here that a network of ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a5c9d9e680ee0e62c8f37ad11a6917
https://doi.org/10.1016/s0014-5793(03)01076-7
https://doi.org/10.1016/s0014-5793(03)01076-7
Autor:
Torild, Wickstrøm, Alan, Clarke, Ingvil, Gausemel, Eric, Horn, Karina, Jørgensen, Imtiaz, Khan, Dimitrios, Mantzilas, Thanushan, Rajanayagam, Dirk-Jan, in 't Veld, William, Trigg
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 57(1)
The level of the translocator protein (TSPO) increases dramatically in microglial cells when the cells are activated in response to neuronal injury and insult. The radiotracer [(18) F]GE-180 binds selectively and with high affinity to TSPO and can th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9536becb9cd35acdf17a446400edca33
https://pubmed.ncbi.nlm.nih.gov/24448744
https://pubmed.ncbi.nlm.nih.gov/24448744
Autor:
Harry, Wadsworth, Paul A, Jones, Wai-Fung, Chau, Clare, Durrant, Naghmeh, Fouladi, Joanna, Passmore, Dennis, O'Shea, Duncan, Wynn, Veronique, Morisson-Iveson, Amanda, Ewan, Mikkel, Thaning, Dimitrios, Mantzilas, Ingvil, Gausemel, Imtiaz, Khan, Andrew, Black, Michelle, Avory, William, Trigg
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(3)
A series of tricyclic compounds have been synthesised and evaluated in vitro for affinity against Translocator protein 18 kDa (TSPO) and for preferred imaging properties. The most promising of the compounds were radiolabelled and evaluated in vivo to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1265dd2071e904eee4ac03f9e25dc25a
https://pubmed.ncbi.nlm.nih.gov/22244939
https://pubmed.ncbi.nlm.nih.gov/22244939
Publikováno v:
Journal of Applied Microbiology. 102
Aim: To purify and analyse antimicrobial substances produced by the tomato pathogen Clavibacter michiganensis ssp. michiganensis (Cmm), with potential application in control of Clavibacter michiganensis ssp. sepedonicus (Cms), the causal agent of bac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a034dad5e032513d88f9a7c8e917430
https://doi.org/10.1111/j.1365-2672.2006.03091.x
https://doi.org/10.1111/j.1365-2672.2006.03091.x