Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Dimitrios L Kalpaxis"'
Autor:
Ourania N Kostopoulou, George E Magoulas, Georgios E Papadopoulos, Athanasia Mouzaki, George P Dinos, Dionissios Papaioannou, Dimitrios L Kalpaxis
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134526 (2015)
As fight against antibiotic resistance must be strengthened, improving old drugs that have fallen in reduced clinical use because of toxic side effects and/or frequently reported resistance, like chloramphenicol (CAM), is of special interest. Chloram
Externí odkaz:
https://doaj.org/article/0ca8fb61f603433ea8dc1089a63d44b3
Autor:
George P. Dinos, Constantinos M. Athanassopoulos, Dionissia A. Missiri, Panagiota C. Giannopoulou, Ioannis A. Vlachogiannis, Georgios E. Papadopoulos, Dionissios Papaioannou, Dimitrios L. Kalpaxis
Publikováno v:
Antibiotics, Vol 5, Iss 2, p 20 (2016)
Chloramphenicol (CAM) is the D-threo isomer of a small molecule, consisting of a p-nitrobenzene ring connected to a dichloroacetyl tail through a 2-amino-1,3-propanediol moiety. CAM displays a broad-spectrum bacteriostatic activity by specifically in
Externí odkaz:
https://doaj.org/article/1c026c2eed274faab59cd55f2b6975d2
Autor:
Dimitrios L. Kalpaxis, Panagiota C. Giannopoulou, Georgia G Kournouto, Eleni Sazakli, George P. Dinos, Michalis Leotsinidis
Publikováno v:
Toxics, Vol 8, Iss 89, p 89 (2020)
Toxics
Volume 8
Issue 4
Toxics
Volume 8
Issue 4
The impact of metals bioaccumulation in marine organisms is a subject of intense investigation. This study was designed to determine the association between oxidative stress induced by seawater enriched with trace metals and protein synthesis using a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee474c72c426eff6386d7c5d220ee9d0
https://doi.org/10.20944/preprints202009.0642.v1
https://doi.org/10.20944/preprints202009.0642.v1
Autor:
Athanasios Tsamandas, Ourania N. Kostopoulou, Dimitrios S. Goumenos, Iason Kyriazis, Panagiotis Kallidonis, Panagiotis Kitrou, Dimitrios L. Kalpaxis, Evangelos Liatsikos, Dimitrios Karnabatidis, Georgios A. Spyroulias, Despoina Liourdi, Kostas D. Marousis
Publikováno v:
Journal of Endourology. 29:580-589
The urothelium represents "the tightest and most impermeable barrier in the body." We investigated the distribution of paclitaxel (PTX) in the ureteral wall after the inflation of a paclitaxel-eluting balloon (PEB) in an attempt to elucidate the poss
Autor:
Dimitrios L. Kalpaxis, Georgia G. Kournoutou, Panagiota C. Giannopoulou, Eleni Sazakli, Michel Leotsinidis
Publikováno v:
Aquatic toxicology (Amsterdam, Netherlands). 192
Numerous studies have shown the ability of trace metals to accumulate in marine organisms and cause oxidative stress that leads to perturbations in many important intracellular processes, including protein synthesis. This study is mainly focused on t
Publikováno v:
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 165:1-8
Polyamines, in particular spermidine and spermine, have been identified as important antioxidants, highly induced by oxidative stress in a variety of organisms. However, little is known about changes in polyamine content of metal-stressed marine orga
Autor:
Athanasia Mouzaki, Ourania N. Kostopoulou, Dionissios Papaioannou, Georgios Papadopoulos, Ekaterini C. Kouvela, Dimitrios L. Kalpaxis, Ioannis Panagoulias, Thomas Garnelis, George E. Magoulas, Maria Rodi, George P. Dinos
Publikováno v:
Nucleic Acids Research
Chloramphenicol (CAM) is a broad-spectrum antibiotic, limited to occasional only use in developed countries because of its potential toxicity. To explore the influence of polyamines on the uptake and activity of CAM into cells, a series of polyamine-
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:472-480
Ketolides, the third generation of expanded-spectrum macrolides, have in the last years become a successful weapon in the endless war against macrolide-resistant pathogens. Ketolides are semisynthetic derivatives of the naturally produced macrolide e
Autor:
Dimitrios L. Kalpaxis, Christos D. Georgiou, Georgia G. Kournoutou, Sofia Pytharopoulou, Michalis Leotsinidis
Publikováno v:
Journal of Hazardous Materials. 260:263-271
The main purpose of this study was to investigate the impact of metal-mediated stress on the protein-synthesis pathway in mussels. To this end, mussels (Mytilus galloprovincialis) underwent a 15 days exposure to 100 μg/L Cu(2+) or Cd(2+). Both metal
Autor:
Konstantinos Grintzalis, Dimitrios L. Kalpaxis, Michel Leotsinidis, Eleni Sazakli, Christos D. Georgiou, Sofia Pytharopoulou
Publikováno v:
Aquatic Toxicology. 105:157-165
Certain metals, like Hg, Cu and Cd, are capable of down-regulating protein synthesis in several marine organisms, including Mytilus galloprovincialis. Nevertheless, due to the complexity of the environmental stress, it is difficult to evaluate the in