Zobrazeno 1 - 10
of 210
pro vyhledávání: '"Dimitrios I. Zeugolis"'
Autor:
Adrian Djalali-Cuevas, Mandy Rettel, Frank Stein, Mikhail Savitski, Stephen Kearns, Jack Kelly, Manus Biggs, Ioannis Skoufos, Athina Tzora, Nikitas Prassinos, Nikolaos Diakakis, Dimitrios I. Zeugolis
Publikováno v:
Materials Today Bio, Vol 25, Iss , Pp 100977- (2024)
Although human tenocytes and dermal fibroblasts have shown promise in tendon engineering, no tissue engineered medicine has been developed due to the prolonged ex vivo time required to develop an implantable device. Considering that macromolecular cr
Externí odkaz:
https://doaj.org/article/5b8a4a72beb64a32962082aa003501bd
Publikováno v:
Advanced NanoBiomed Research, Vol 4, Iss 1, Pp n/a-n/a (2024)
Cells sense extracellular matrix‐induced biophysical signals, which are transduced into intracellular signaling cascades, and trigger a series of cell responses, including adhesion, migration, and lineage commitment. Traditionally, in in vitro cont
Externí odkaz:
https://doaj.org/article/54e6655452c549dd9172c97f47fa5cf0
Autor:
Sofia Ribeiro, Eugenia Pugliese, Stefanie H. Korntner, Emanuel M. Fernandes, Manuela E. Gomes, Rui L. Reis, Alan O'Riordan, Stephen Kearns, Jack L. Kelly, Manus Biggs, Yves Bayon, Dimitrios I. Zeugolis
Publikováno v:
Biomedical Engineering Advances, Vol 6, Iss , Pp 100098- (2023)
Tissue engineering strategies for tendon repair and regeneration rely heavily on the use of tendon derived cells. However, these cells frequently undergo phenotypic drift in vitro, which compromises their therapeutic potential. In order to maintain t
Externí odkaz:
https://doaj.org/article/4bbc8c49c86e4384b796d34f1db7d478
Publikováno v:
Life, Vol 14, Iss 4, p 435 (2024)
Even though tissue-engineered medicines are under intense academic, clinical, and commercial investigation, only a handful of products have been commercialised, primarily due to the costs associated with their prolonged manufacturing. While macromole
Externí odkaz:
https://doaj.org/article/ba5255e5dedf4182bd0074737ea91cc2
Autor:
Christina N.M. Ryan, Eugenia Pugliese, Naledi Shologu, Diana Gaspar, Peadar Rooney, Md Nahidul Islam, Alan O'Riordan, Manus J. Biggs, Matthew D. Griffin, Dimitrios I. Zeugolis
Publikováno v:
Biomaterials and Biosystems, Vol 11, Iss , Pp 100079- (2023)
Due to their inherent plasticity, dermal fibroblasts hold great promise in regenerative medicine. Although biological signals have been well-established as potent regulators of dermal fibroblast function, it is still unclear whether physiochemical cu
Externí odkaz:
https://doaj.org/article/0c197c3228874bf5bd13c62a5869656e
Autor:
Sofia Ribeiro, Eugenia Pugliese, Stefanie H. Korntner, Emanuel M. Fernandes, Manuela E. Gomes, Rui L. Reis, Alan O'Riordan, Yves Bayon, Dimitrios I. Zeugolis
Publikováno v:
Engineering in Life Sciences, Vol 22, Iss 10, Pp 619-633 (2022)
Abstract The combined effect of surface topography and substrate rigidity in stem cell cultures is still under‐investigated, especially when biodegradable polymers are used. Herein, we assessed human bone marrow stem cell response on aliphatic poly
Externí odkaz:
https://doaj.org/article/feabdfdf044a46209fca24b5451c9ab8
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-19 (2022)
Abstract Foot ulceration is a major complication of diabetes mellitus, which results in significant human suffering and a major burden on healthcare systems. The cause of impaired wound healing in diabetic patients is multifactorial with contribution
Externí odkaz:
https://doaj.org/article/15ee09c1c3344e4688649ff41c80a073
Autor:
Eugenia Pugliese, Ignacio Sallent, Sofia Ribeiro, Alexandre Trotier, Stefanie H. Korntner, Yves Bayon, Dimitrios I. Zeugolis
Publikováno v:
Materials Today Bio, Vol 19, Iss , Pp 100584- (2023)
Enthesis repair remains a challenging clinical indication. Herein, a three-layer scaffold composed of a tendon-like layer of collagen type I, a fibrocartilage-like layer of collagen type II and a bone-like layer of collagen type I and hydroxyapatite,
Externí odkaz:
https://doaj.org/article/05877c7403a242a5aacdae22cda0acd8
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Background: Cell culture media containing undefined animal-derived components and prolonged in vitro culture periods in the absence of native extracellular matrix result in phenotypic drift of human bone marrow stromal cells (hBMSCs).Methods: Herein,
Externí odkaz:
https://doaj.org/article/c6712ead920a4bdb9828366c032d11c1
Autor:
Caglar Ersanli, Chrysoula (Chrysa) Voidarou, Athina Tzora, Konstantina Fotou, Dimitrios I. Zeugolis, Ioannis Skoufos
Publikováno v:
Journal of Functional Biomaterials, Vol 14, Iss 9, p 481 (2023)
Herbal extracts have been used in traditional remedies since the earliest myths. They have excellent antimicrobial, anti-inflammatory, and antioxidant activities owing to various bioactive components in their structure. However, due to their inabilit
Externí odkaz:
https://doaj.org/article/12bebdbc66094d7aae8253f593d00f82