Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Dimitrios Gatos"'
Solid-Phase Synthesis of 2-Benzothiazolyl and 2-(Aminophenyl)benzothiazolyl Amino Acids and Peptides
Publikováno v:
Molecules, Vol 28, Iss 14, p 5412 (2023)
2-benzothiazoles and 2-(aminophenyl)benzothiazoles represent biologically interesting heterocycles with high pharmacological activity. The combination of these heterocycles with amino acids and peptides is of special interest, as such structures comb
Externí odkaz:
https://doaj.org/article/d5c1bc4b9d3643f68c6ce5226bde464a
Publikováno v:
Molecules, Vol 25, Iss 1, p 218 (2020)
Thioether containing peptides were obtained following three synthetic routes. In route A, halo acids esterified on 2-chlorotrityl(Cltr) resin were reacted with N-fluorenylmethoxycarbonyl (Fmoc) aminothiols. These were either cleaved from the resin to
Externí odkaz:
https://doaj.org/article/d3dd34c8aa3a497fb8ded99716be55aa
Autor:
Theodore Tselios, Mihalis Aggelidakis, Anthi Tapeinou, Vivian Tseveleki, Ioannis Kanistras, Dimitrios Gatos, John Matsoukas
Publikováno v:
Molecules, Vol 19, Iss 11, Pp 17968-17984 (2014)
Experimental autoimmune encephalomyelitis (EAE) is a demyelinating disease of the central nervous system and is an animal model of multiple sclerosis (MS). Although the etiology of MS remains unclear, there is evidence T-cell recognition of immunodom
Externí odkaz:
https://doaj.org/article/c76c0bc6598c41e2a3a6f2d37628313c
Publikováno v:
Molecules, Vol 24, Iss 23, p 4261 (2019)
N-mercaptoalkylglycine residues were inserted into peptides by reacting N-free amino groups of peptides, which were initially synthesized on 2-chlorotrityl resin (Cltr) using the Fmoc/tBu method, with bromoacetic acid and subsequent nucleophilic repl
Externí odkaz:
https://doaj.org/article/f80b220065fb4f3f8ff28ecff74f3053
Autor:
Spyridon Mourtas, Panayiota Christodoulou, Pavlos Klepetsanis, Dimitrios Gatos, Kleomenis Barlos, Sophia G. Antimisiaris
Publikováno v:
Molecules, Vol 24, Iss 8, p 1540 (2019)
Amyloid β (Aβ) species are considered as potential targets for the development of diagnostics/therapeutics towards Alzheimer’s disease (AD). Nanoliposomes which are decorated with molecules having high affinity for Aβ species may be considered a
Externí odkaz:
https://doaj.org/article/7d108859d5f64cf69708e7ffaeead530
Publikováno v:
Molecules
Volume 25
Issue 1
Molecules, Vol 25, Iss 1, p 218 (2020)
Volume 25
Issue 1
Molecules, Vol 25, Iss 1, p 218 (2020)
Thioether containing peptides were obtained following three synthetic routes. In route A, halo acids esterified on 2-chlorotrityl(Cltr) resin were reacted with N-fluorenylmethoxycarbonyl (Fmoc) aminothiols. These were either cleaved from the resin to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c6b6e2cae51cf8d736269675a5528d
http://europepmc.org/articles/PMC6983143
http://europepmc.org/articles/PMC6983143
Publikováno v:
Amino Acids. 49:995-1004
Chloramphenicol peptides were recently established as useful tools for probing nascent polypeptide chain interaction with the ribosome, either biochemically, or structurally. Here, we present a new 10mer chloramphenicol peptide, which exerts a dual i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8a23f4e9b787252de26197518d92cf
https://doi.org/10.1007/s00726-017-2406-5
https://doi.org/10.1007/s00726-017-2406-5
Autor:
Kirsty Elizabeth High, Theodore Tselios, Matthaia Ieronymaki, Kirsty Penkman, Dimitrios Gatos, Anna Pantelia, Irene Friligou, Maria Eleni Androutsou, Molly Crisp
Publikováno v:
Biopolymers. 104:506-514
A fast and efficient microwave (MW)-assisted solid-phase peptide synthesis protocol using the 2-chlorotrityl chloride resin and the Fmoc/tBu methodology, has been developed. The established protocol combines the advantages of MW irradiation and the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8303d3da56e9a5bf4d378302b11d7cd6
https://doi.org/10.1002/bip.22710
https://doi.org/10.1002/bip.22710
Autor:
Nikolaos Dimisianos, Fotios Karagiannis, Athanasia Mouzaki, Loukas Synodinos, Theodore Tselios, Dimitrios Gatos, Vasso Apostolopoulos, George Deraos, Panayiotis Plotas, Panagiotis Papathanasopoulos, Kokona Chatzantoni, Apostolos Papalois, Hubert Kalbacher, John Matsoukas, Maria Rodi
Publikováno v:
European Journal of Medicinal Chemistry. 101:13-23
Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous system, and it has been established that autoreactive T helper (Th) cells play a crucial role in its pathogenesis. Myelin basic protein (MBP) epitopes are major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5766645d0b78fa5c4b981fca806227b3
https://doi.org/10.1016/j.ejmech.2015.06.015
https://doi.org/10.1016/j.ejmech.2015.06.015
Autor:
Ioannis Kanistras, Anthi Tapeinou, Dimitrios Gatos, Vivian Tseveleki, Mihalis Aggelidakis, Theodore Tselios, John Matsoukas
Publikováno v:
Molecules
Volume 19
Issue 11
Pages 17968-17984
Molecules, Vol 19, Iss 11, Pp 17968-17984 (2014)
Volume 19
Issue 11
Pages 17968-17984
Molecules, Vol 19, Iss 11, Pp 17968-17984 (2014)
Experimental autoimmune encephalomyelitis (EAE) is a demyelinating disease of the central nervous system and is an animal model of multiple sclerosis (MS). Although the etiology of MS remains unclear, there is evidence T-cell recognition of immunodom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26cae54def0b467373800db01a12904d
http://europepmc.org/articles/PMC6270842
http://europepmc.org/articles/PMC6270842