Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Dimitrios Chondros"'
Autor:
Song Wang, Cecilie L. Bager, Morten A. Karsdal, Dimitrios Chondros, Darin Taverna, Nicholas Willumsen
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Background Extensive extracellular matrix (ECM) remodeling is a hallmark of metastatic pancreatic ductal adenocarcinoma (mPDA). We investigated fragments of collagen types III (C3M, PRO-C3), VI (PRO-C6), and VIII (C8-C), and versican (VCANM)
Externí odkaz:
https://doaj.org/article/ba7e25ea26134c6bb7ed23c4b9dd9e92
Autor:
Eric, Van Cutsem, Margaret A, Tempero, Darren, Sigal, Do-Youn, Oh, Nicola, Fazio, Teresa, Macarulla, Erika, Hitre, Pascal, Hammel, Andrew E, Hendifar, Susan E, Bates, Chung-Pin, Li, Sunil R, Hingorani, Christelle, de la Fouchardiere, Anup, Kasi, Volker, Heinemann, Anthony, Maraveyas, Nathan, Bahary, Laura, Layos, Vaibhav, Sahai, Lei, Zheng, Jill, Lacy, Joon Oh, Park, Fabienne, Portales, Paul, Oberstein, Wilson, Wu, Dimitrios, Chondros, Andrea J, Bullock
Publikováno v:
Scientia
Journal of Clinical Oncology
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Journal of Clinical Oncology
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
PURPOSE To evaluate the efficacy and safety of pegvorhyaluronidase alfa (PEGPH20) plus nab-paclitaxel/gemcitabine (AG) in patients with hyaluronan-high metastatic pancreatic ductal adenocarcinoma (PDA). PATIENTS AND METHODS HALO 109-301 was a phase I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8b97ebf9ba99cec6f3515308b207bd
https://hdl.handle.net/11351/6453
https://hdl.handle.net/11351/6453
Autor:
Fadi Braiteh, Dimitrios Chondros, Mark M. Zalupski, Ping Jiang, Andrea Wang-Gillam, Jie Pu, Paul E. Oberstein, W. Wu, Paul S. Ritch, Tara Elisabeth Seery, Sihem Khelifa, Darren Sigal, William P. Harris, Nathan Bahary, Carrie Aldrich, Sunil R. Hingorani, Andrew Eugene Hendifar, Lei Zheng, Andrea J. Bullock
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 36(4)
Purpose Metastatic pancreatic ductal adenocarcinoma is characterized by excessive hyaluronan (HA) accumulation in the tumor microenvironment, elevating interstitial pressure and impairing perfusion. Preclinical studies demonstrated pegvorhyaluronidas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6b7fd3c05e08299516730e34fd3ca8c
https://pubmed.ncbi.nlm.nih.gov/29684975
https://pubmed.ncbi.nlm.nih.gov/29684975
Autor:
Ping Jiang, Jie Pu, F. Lian, Andrea J. Bullock, Mark M. Zalupski, Tara Elisabeth Seery, W. Wu, Paul S. Ritch, Sunil R. Hingorani, Nathan Bahary, Andrew Eugene Hendifar, Fadi Braiteh, Lei Zheng, William P. Harris, Darren Sigal, Junming Zhu, Dimitrios Chondros
Publikováno v:
Annals of Oncology. 28:v253-v254
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f5be0e3ac79c5ab82c144664ed9a305
https://doi.org/10.1093/annonc/mdx369.126
https://doi.org/10.1093/annonc/mdx369.126
Autor:
Darren Sigal, C.-P. Li, Pippa Corrie, Vaibhav Sahai, Y.-J. Bang, Philip A. Philip, Dimitrios Chondros, D-Y. Oh, Michel Ducreux, E. Van Cutsem, C. Berman, A. Baron, Margaret A. Tempero, Michele Reni, Andrew Eugene Hendifar, Lei Zheng, Andrea J. Bullock, Mark M. Zalupski
Publikováno v:
Annals of Oncology. 29:viii270
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbe81663752dd292acea4fbdc823f91b
https://doi.org/10.1093/annonc/mdy282.172
https://doi.org/10.1093/annonc/mdy282.172
Publikováno v:
Journal of Clinical Oncology. 36:461-461
461 Background: Pancreatic ductal adenocarcinoma (PDA) is highly associated with thromboembolic events (TEs). There is no consensus for prophylaxis of TEs across thromboprophylactic guidelines in ambulatory patient settings. Published ASCO (2014) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4af4e6b0993ef7c71754c7d2c528cf68
https://doi.org/10.1200/jco.2018.36.4_suppl.461
https://doi.org/10.1200/jco.2018.36.4_suppl.461
Autor:
Do-Youn Oh, Mann Muhsin, Dimitrios Chondros, Rachna T. Shroff, Ghassan K. Abou-Alfa, Paul S. Ritch, J. Randolph Hecht, Andrea J. Bullock, Mitesh J. Borad
Publikováno v:
Journal of Clinical Oncology. 36:TPS543-TPS543
TPS543 Background: Cholangiocarcinoma (CCA) is treated with CIS and GEM (CISGEM), but prognosis is poor. Hyaluronan (HA) accumulation in solid tumors may impede drug and immune cell access. PEGPH20 targets tumors that accumulate HA (HA-high). This st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efb7e5ae71826a1922e35964a62f643c
https://doi.org/10.1200/jco.2018.36.4_suppl.tps543
https://doi.org/10.1200/jco.2018.36.4_suppl.tps543
Autor:
Carrie Aldrich, Tara Elisabeth Seery, Andrea J. Bullock, Dimitrios Chondros, W. Wu, Mark M. Zalupski, Darren Sigal, Fadi Braiteh, Ping Jiang, Paul S. Ritch, Sunil R. Hingorani, Andrew Eugene Hendifar, Lei Zheng, Jie Pu, William P. Harris, Sihem Khelifa, Nathan Bahary
Publikováno v:
Annals of Oncology. 28:v261
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3ec386afed4cb80edf3c33c6864188a
https://doi.org/10.1093/annonc/mdx369.145
https://doi.org/10.1093/annonc/mdx369.145
Autor:
William P. Harris, Andrew Eugene Hendifar, Eric Van Cutsem, Lei Zheng, Tara Elisabeth Seery, Andrea J. Bullock, Dimitrios Chondros, Michel Ducreux, Pippa G. Corrie, Michele Reni
Publikováno v:
Cancer Research. 77:CT066-CT066
Background: Poor outcome in pancreatic ductal adenocarcinoma (PDA) is associated partly with stromal hyaluronan (HA) accumulation, which may compromise chemotherapy access to tumors. In animal models, PEGPH20 degrades HA in tumors. Key endpoint data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::946aa542ebf31f8e1eae85fe5c206c93
https://doi.org/10.1158/1538-7445.am2017-ct066
https://doi.org/10.1158/1538-7445.am2017-ct066
Autor:
Tara Elisabeth Seery, Michel Ducreux, C.-P. Li, Pippa Corrie, Andrea J. Bullock, Michele Reni, Y.-J. Bang, E. Van Cutsem, William P. Harris, Dimitrios Chondros, Andrew Eugene Hendifar, Lei Zheng, D-Y. Oh
Publikováno v:
Annals of Oncology. 28:iii24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99fa481bbebe386656ee8ba604f8c256
https://doi.org/10.1093/annonc/mdx261.042
https://doi.org/10.1093/annonc/mdx261.042