Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Dimitrios, Mougiakakos"'
Autor:
Tobias Ronny Haage, Emmanouil Charakopoulos, Vikas Bhuria, Conny K. Baldauf, Mark Korthals, Juliane Handschuh, Peter Müller, Juan Li, Kunjan Harit, Gopala Nishanth, Stephanie Frey, Martin Böttcher, Klaus-Dieter Fischer, Jan Dudeck, Anne Dudeck, Daniel B. Lipka, Burkhart Schraven, Anthony R. Green, Andreas J. Müller, Dimitrios Mougiakakos, Thomas Fischer
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-23 (2024)
Abstract Background Neutrophils play a crucial role in inflammation and in the increased thrombotic risk in myeloproliferative neoplasms (MPNs). We have investigated how neutrophil-specific expression of JAK2-V617F or CALRdel re-programs the function
Externí odkaz:
https://doaj.org/article/de0cb7b1744d4527b1c4f8287f2223f4
Autor:
Dimitrios Mougiakakos
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/2e5a0e2aa1604febaf725721ea591aa0
Autor:
Vikas Bhuria, Tobias Franz, Conny Baldauf, Martin Böttcher, Nicolas Chatain, Steffen Koschmieder, Tim H. Brümmendorf, Dimitrios Mougiakakos, Burkhart Schraven, Sascha Kahlfuß, Thomas Fischer
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Background Calcium (Ca2+) signaling regulates various vital cellular functions, including integrin activation and cell migration. Store-operated calcium entry (SOCE) via calcium release-activated calcium (CRAC) channels represents a major pa
Externí odkaz:
https://doaj.org/article/db493b9498e045b9a9db0c8fc03508d6
Autor:
Alexander Biedermann, Maria Patra-Kneuer, Dimitrios Mougiakakos, Maike Büttner-Herold, Doris Mangelberger-Eberl, Johannes Berges, Christian Kellner, Sarah Altmeyer, Jörg Thomas Bittenbring, Christian Augsberger, Kristina Ilieva-Babinsky, Stefan Haskamp, Fabian Beier, Christopher Lischer, Julio Vera, Anja Lührmann, Simone Bertz, Simon Völkl, Benedikt Jacobs, Stefan Steidl, Andreas Mackensen, Heiko Bruns
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Macrophages are one of the key mediators of the therapeutic effects exerted by monoclonal antibodies, such as the anti-CD19 antibody tafasitamab, approved in combination with lenalidomide for the treatment of relapsed or refractory (r/r) diffuse larg
Externí odkaz:
https://doaj.org/article/83e0d53a47ba41ce83058f40a666be1f
Autor:
Lukas Häselbarth, Sara Gamali, Domenica Saul, Manuela Krumbholz, Romy Böttcher-Loschinski, Martin Böttcher, Deyu Zou, Markus Metzler, Axel Karow, Dimitrios Mougiakakos
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Chronic myeloid leukemia (CML) is effectively treated with tyrosine kinase inhibitors (TKIs), targeting the BCR::ABL1 oncoprotein. Still, resistance to therapy, relapse after treatment discontinuation, and side effects remain significant iss
Externí odkaz:
https://doaj.org/article/21d4649d4b6548ffaf9e27d12209e88a
Autor:
Denis M. Schewe, Fotini Vogiatzi, Ira A. Münnich, Tobias Zeller, Roland Windisch, Christian Wichmann, Kristina Müller, Hilal Bhat, Elisa Felix, Dimitrios Mougiakakos, Heiko Bruns, Lennart Lenk, Thomas Valerius, Andreas Humpe, Matthias Peipp, Christian Kellner
Publikováno v:
HemaSphere, Vol 8, Iss 2, Pp n/a-n/a (2024)
Abstract CD19‐directed immunotherapy has become a cornerstone in the therapy of B‐cell precursor acute lymphoblastic leukemia (BCP‐ALL). CD19‐directed cellular and antibody‐based therapeutics have entered therapy of primary and relapsed dis
Externí odkaz:
https://doaj.org/article/9fd66e3abc514ac88a3fe38bc7edfa67
Publikováno v:
RMD Open, Vol 9, Iss 4 (2023)
Autoimmune disorders occur when immune cells go wrong and attack the body’s own tissues. Currently, autoimmune disorders are largely treated by broad immunosuppressive agents and blocking antibodies, which can manage the diseases but often are not
Externí odkaz:
https://doaj.org/article/f23e0b3ee37445099126896b758290ec
Autor:
Francesca Sacco, Giorgia Massacci, Venafra Veronica, Valeria Bica, Sara Latini, Thomas Fischer, Dimitrios Mougiakakos, Martin Böttcher, Livia Perfetto, Natalie Krahmer, Felix Klingelhuber, Monia Pugliese
Publikováno v:
HemaSphere, Vol 7, p e310578d (2023)
Externí odkaz:
https://doaj.org/article/65da723653484a1c9710aed59454bb77
Autor:
Vikas Bhuria, Tobias Franz, Conny Baldauf, Martin Böttcher, Nicolas Chatain, Steffen Koschmieder, Tim H Brümmendorf, Dimitrios Mougiakakos, Burkhart Schraven, Sascha Kahlfuß, Thomas Fischer
Publikováno v:
HemaSphere, Vol 7, p e21609c8 (2023)
Externí odkaz:
https://doaj.org/article/5506c27cb8d042049a0c79cc874e1248
Autor:
Vanja Zeremski, Siegfried Kropf, Michael Koehler, Niklas Gebauer, Ellen D. McPhail, Thomas Habermann, Francesca Schieppati, Dimitrios Mougiakakos
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Background and aimHigh-grade B cell lymphomas with concomitant MYC and BCL2 and/or BCL6 rearrangements (HGBCL-DH/TH) have a poor prognosis when treated with the standard R-CHOP-like chemoimmunotherapy protocol. Whether this can be improved using inte
Externí odkaz:
https://doaj.org/article/484559a385b44966ac79785b972561b2