Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Dimitrina D Pravtcheva"'
Autor:
Anthony Chang, Ying Wang, Dimitrina D Pravtcheva, David A. Dean, Dilip K. Deb, Richard C Geiger, Shenglin Chen, Kathleen Othelia Heilig, Youli Wang, Minghui Xiang, Charles W. Heilig, Andrew W. Minto, Martin Schlimme
Publikováno v:
Laboratory Investigation. 90:83-97
Reduced nephron numbers may predispose to renal failure. We hypothesized that glucose transporters (GLUTs) may contribute to progression of the renal disease, as GLUTs have been implicated in diabetic glomerulosclerosis and hypertensive renal disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508551f56dbb33590a716c612eb5311d
https://doi.org/10.1038/labinvest.2009.95
https://doi.org/10.1038/labinvest.2009.95
Publikováno v:
Molecular Reproduction and Development. 75:1678-1687
Mammals with excess insulin-like growth factor 2 (IGFII) during embryogenesis have developmental defects that can lead to perinatal lethality. In adults, higher levels of IGFII increase the risk of cancer and may accelerate the development of atheros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec65878770573fb3ef5068233dff504
https://doi.org/10.1002/mrd.20909
https://doi.org/10.1002/mrd.20909
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 529:35-50
Foreign DNA injected into mouse embryos integrates into the host chromosomes and is usually transmitted stably to the progeny. Rare cases of transgene instability have been described, and these can help our understanding of the rules that govern the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be346d468b81c3dcc6496501ce184c3a
https://doi.org/10.1016/s0027-5107(03)00110-6
https://doi.org/10.1016/s0027-5107(03)00110-6
Publikováno v:
Genomics. 72:78-87
Oligosyndactylism (Os) is a radiation-induced mouse mutation associated with recessive lethality and a dominant effect on limb and kidney development. The lethal effect of the mutation is due to a cell-autonomous block in the transition from metaphas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b26aa40210ef8f672f3daf1150634e
https://doi.org/10.1006/geno.2001.6474
https://doi.org/10.1006/geno.2001.6474
Publikováno v:
Genomics. 60:258-271
CpG islands are GC-rich regions located in the promoter regions of housekeeping genes and many tissue-specific genes. While most CpG islands are normally unmethylated, island methylation can occur and is associated with silencing of the corresponding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ac79635ba9a0c05dfac4ed2a8fa30a
https://doi.org/10.1006/geno.1999.5921
https://doi.org/10.1006/geno.1999.5921
Publikováno v:
The Journal of Experimental Zoology. 281:43-57
The insulin-like growth factor II is mitogenic for a number of cell types and can inhibit apoptosis. The frequent expression of this gene in human and experimental animal tumors indicates that insulin-like growth factor-2 may play an important role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d19f5c617866284b88b6227ed888a89d
https://doi.org/10.1002/(sici)1097-010x(19980501)281:1<43::aid-jez7>3.0.co
https://doi.org/10.1002/(sici)1097-010x(19980501)281:1<43::aid-jez7>3.0.co
Publikováno v:
Molecular Reproduction and Development. 48:194-207
The insulin-like growth factor II (IGFII) is a mitogen for a number of cell types in vitro and is required for normal embryonic growth. It has been hypothesized that overexpression of IGF2 is responsible for the increased growth and tumor predisposit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a6dea224f7af0d55791410ea734ce33
https://doi.org/10.1002/(sici)1098-2795(199710)48:2<194::aid-mrd7>3.0.co
https://doi.org/10.1002/(sici)1098-2795(199710)48:2<194::aid-mrd7>3.0.co
Publikováno v:
Genetics. 144:1747-1756
Oligosyndactylism (Os) is a radiation-induced mutation on mouse chromosome 8 associated with early postimplantation lethality in homozygotes and abnormal development of the limbs and kidneys in heterozygotes. The recessive lethal effect of Os is due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::859916844709c3056b14ccadc9bd5ae3
https://doi.org/10.1093/genetics/144.4.1747
https://doi.org/10.1093/genetics/144.4.1747
Autor:
Christine Alibert, Frank H. Ruddle, Dimitrina D. Pravtcheva, Antony P. Jackson, Michelle M. LeBeau, Sreenivasan Ponnambalam, Peter Parham
Publikováno v:
Genomics. 24:440-444
Two human clathrin light-chain genes have been defined. The gene (CLTA) encoding the LCa light chain maps to the long arm of chromosome 12 at 12q23-q24 and that encoding the LCb light chain (CLTB) maps to the long arm of chromosome 4 at 4q2-q3. Isola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22330c02d58b7bdd9980acfede1aefb9
https://doi.org/10.1006/geno.1994.1650
https://doi.org/10.1006/geno.1994.1650
Publikováno v:
Journal of Experimental Zoology. 268:452-468
The sensitivity of small transgenes to position effects on their expression suggests that they could serve as indicators of the chromatin properties at their integration site. In particular, they might be expected to provide information on the functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00d5faaa9c2e258083c9f8351a5cbb3
https://doi.org/10.1002/jez.1402680606
https://doi.org/10.1002/jez.1402680606