Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Dimitrij Plachov"'
Autor:
Olga Okladnova, Susanne Schneider, Anna Maria Musti, Andrej Poleev, Brigitta Royer-Pokora, Dimitrij Plachov
Publikováno v:
Scopus-Elsevier
The conserved structure of the transcription factors of the Pax gene family may reflect functional conservation. We have demonstrated that the human Pax8 transcription factor is organized in several functional domains and contains two regions respons
Publikováno v:
Genomics. 42:452-461
λ phage clones containing the murine Pax 8 gene were isolated from a C57BL/6 kidney genomic mouse library using mouse cDNA fragments as probes. A clone encompassing about 16 kb of the 5′ untranslated region of the murine Pax 8 gene was isolated fr
Autor:
Helmut Fickenscher, Stefan Mundlos, Bernhard Zabel, Andreas Winterpacht, Andrew Fidler, Peter Gruss, Andrej Poleev, Dimitrij Plachov
Publikováno v:
Development. 116:611-623
Recent evidence indicates a crucial role for paired box genes in mouse and human embryogenesis. The murine Pax8 gene encodes a sequence-specific transcription factor and is expressed in the developing secretory system as well as in the developing and
Autor:
Kamal Chowdhury, Claudia Walther, Jean-Louis Guénet, Dominique Simon, Peter Gruss, Dimitrij Plachov
Publikováno v:
Development. 110:643-651
Several mouse genes designated ‘Pax genes’ contain a highly conserved DNA sequence homologous to the paired box of Drosophila. Here we describe the isolation of Pax8, a novel paired box containing clone from an 8.5 day p.c. mouse embryo cDNA libr
Publikováno v:
Molecular and cellular biology. 12(9)
The Pax-8 gene, a member of the murine family of paired box-containing genes (Pax genes), is expressed in adult thyroid and in cultured thyroid cell lines. The Pax-8 protein binds, through its paired domain, to the promoters of thyroglobulin and thyr
Autor:
Peter Gruss, Dominique Simon, Birgit Jostes, Claudia Walther, Rudi Balling, Jean-Louis Guénet, Martyn Goulding, Dimitrij Plachov, Urban Deutsch
Publikováno v:
Genomics. 11(2)
A murine multigene family has been identified that shares a conserved sequence motif, the paired box, with developmental control and tissue-specific genes of Drosophila. To date five murine pai red bo x -containing genes (Pax genes) have been describ
Autor:
Margot Meyer-Delius, Dimitrij Plachov, Gernot Gradehandt, Hans-Gregor Gattner, Johannes Hampl, Hubert Kalbacher, Wolfgang Voelter, Erwin Rüde
Publikováno v:
Molecular immunology. 28(4-5)
The requirements for insulin presentation and recognition by A alpha b A beta b- and A alpha b A beta k-restricted mouse T cells were studied using a variety of derivatives of the insulin A chain. It was found that A chain peptides with irreversibly
Publikováno v:
Immunological reviews. 106
In this study we investigated aspects of antigen processing using insulin and insulin A chain-derived fragments as model antigens in Ab alpha Ak beta-restricted T-cell stimulation. Similarly to other proteins, the immunodominant region of insulin rec
Publikováno v:
Molecular immunology. 25(7)
A series of T cell clones was developed from (B10 × B10.BR)F1 mice immunized with the isolated A chain of pig insulin. The T cell clones show considerable diversity as denned by their distinct reactivities to pig, beef, sheep and horse insulins in c