Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Dimitri Conomos"'
Autor:
Hannah Crimmins, David Guérit, Dimitri Conomos, Agnel Sfeir, Emmanuelle Querido, Michael Joseph Smith, Pascal Chartrand, Emilie Pourret, Hadrien Laprade
Extension of telomeres is a critical step in the immortalization of cancer cells. This complex reaction requires proper spatio-temporal coordination of telomerase and telomeres, and remains poorly understood at the cellular level. To understand how c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cfb21475dbc7fb9a2cae4dbda2e7f51
Autor:
Emmanuelle Querido, Dimitri Conomos, Michael Joseph Smith, Agnel Sfeir, Emilie Pourret, David Guérit, Hadrien Laprade, Pascal Chartrand, Hannah Crimmins
Publikováno v:
Molecular Cell. 79:115-126.e6
Extension of telomeres is a critical step in the immortalization of cancer cells. This complex reaction requires proper spatiotemporal coordination of telomerase and telomeres and remains poorly understood at the cellular level. To understand how can
Autor:
Dimitri Conomos, Roger R. Reddel, Mark Hills, Rebecca A. Dagg, Michael D. Stutz, Hilda A. Pickett, Michael Lee, Loretta Lau
Publikováno v:
Nucleic Acids Research
Telomeres are terminal repetitive DNA sequences on chromosomes, and are considered to comprise almost exclusively hexameric TTAGGG repeats. We have evaluated telomere sequence content in human cells using whole-genome sequencing followed by telomere
Publikováno v:
Nature structuralmolecular biology. 21(9)
Alternative lengthening of telomeres (ALT) is a homologous recombination (HR)-dependent mechanism for de novo synthesis of telomeric DNA in mammalian cells. Nuclear receptors are bound to the telomeres of cells that use ALT. Here we demonstrate that
Publikováno v:
Frontiers in Oncology, Vol 3 (2013)
Frontiers in Oncology
Frontiers in Oncology
To escape from the normal limits on proliferative potential, cancer cells must employ a means to counteract the gradual telomere attrition that accompanies semi-conservative DNA replication. While the majority of human cancers do this by up-regulatin
Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells
Autor:
Michael D. Stutz, Mark Hills, Roger R. Reddel, Dimitri Conomos, Hilda A. Pickett, Axel A. Neumann, Tracy M. Bryan
Publikováno v:
The Journal of Cell Biology
Variant repeats interspersed throughout ALT telomeres recruit nuclear receptors, leading to the destabilized telomere architecture and enhanced telomeric recombination.
Telomeres in cells that use the recombination-mediated alternative lengtheni
Telomeres in cells that use the recombination-mediated alternative lengtheni
Autor:
Jeffrey B. Pettis, Maria Gwyn McDowell, Augustine Casiday, Peter C. Bouteneff, Dimitri Conomos, Matthew J. Pereira, John A. McGuckin, George E. Demacopoulos, Sotirios A. Vlavianos, Theodor Damian, Philip Zymaris, Andrew Louth, Marcus Plested, Konstantin Gavrilkin, Julia Konstantinovsky, Theodore G. Stylianopoulos, Vera Shevzov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e72266584e02f190578f6b31da95cfec
https://doi.org/10.1002/9781444392555.ch16
https://doi.org/10.1002/9781444392555.ch16
Autor:
Justin M. Lasser, Dimitri Conomos, John A. McGuckin, Matthew J. Pereira, Jeffrey B. Pettis, Nicholas Birns, Sergey Trostyanskiy, M. C. Steenberg, Sotirios A. Vlavianos, Maria Gwyn McDowell, Philip Zymaris, Thomas Kitson, John Chryssavgis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4074c63b4770d538f3dacff58b77c34
https://doi.org/10.1002/9781444392555.ch1
https://doi.org/10.1002/9781444392555.ch1