Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Dimitri Avramopoulos"'
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-20 (2022)
Abstract Multifactorial diseases are characterized by inter-individual variation in etiology, age of onset, and penetrance. These diseases tend to be relatively common and arise from the combined action of genetic and environmental factors; however,
Externí odkaz:
https://doaj.org/article/3898560943bc4ba1a5fd657cbd35d2ad
Autor:
Gwenn S. Smith, Hillary Protas, Hiroto Kuwabara, Alena Savonenko, Najlla Nassery, Neda F. Gould, Michael Kraut, Dimitri Avramopoulos, Daniel Holt, Robert F. Dannals, Ayon Nandi, Yi Su, Eric M. Reiman, Kewei Chen
Publikováno v:
NeuroImage: Clinical, Vol 37, Iss , Pp 103322- (2023)
Background: Degeneration of the serotonin system has been observed in Alzheimer’s disease (AD) and in mild cognitive impairment (MCI). In transgenic amyloid mouse models, serotonin degeneration is detected prior to widespread cortical beta-amyloid
Externí odkaz:
https://doaj.org/article/9f77b3ae48cb4778880522ffadcdb828
Autor:
Gwenn S. Smith, Clifford I. Workman, Hillary Protas, Yi Su, Alena Savonenko, Hiroto Kuwabara, Neda F. Gould, Michael Kraut, Jin Hui Joo, Ayon Nandi, Dimitri Avramopoulos, Eric M. Reiman, Kewei Chen
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Depression in late-life is associated with increased risk of cognitive decline and development of all-cause dementia. The neurobiology of late-life depression (LLD) may involve both neurochemical and neurodegenerative mechanisms that are com
Externí odkaz:
https://doaj.org/article/01ad391dea8843638cdd171ec1cb677d
Autor:
Michel Guipponi, Federico A Santoni, Vincent Setola, Corinne Gehrig, Maud Rotharmel, Macarena Cuenca, Olivier Guillin, Dimitris Dikeos, Georgios Georgantopoulos, George Papadimitriou, Logos Curtis, Alexandre Méary, Franck Schürhoff, Stéphane Jamain, Dimitri Avramopoulos, Marion Leboyer, Dan Rujescu, Ann Pulver, Dominique Campion, David P Siderovski, Stylianos E Antonarakis
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141630 (2015)
Externí odkaz:
https://doaj.org/article/963ed32e16e74ae781d3e8f65c32befa
Autor:
Michel Guipponi, Federico A Santoni, Vincent Setola, Corinne Gehrig, Maud Rotharmel, Macarena Cuenca, Olivier Guillin, Dimitris Dikeos, Georgios Georgantopoulos, George Papadimitriou, Logos Curtis, Alexandre Méary, Franck Schürhoff, Stéphane Jamain, Dimitri Avramopoulos, Marion Leboyer, Dan Rujescu, Ann Pulver, Dominique Campion, David P Siderovski, Stylianos E Antonarakis
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112745 (2014)
Schizophrenia (SCZ) is a severe, debilitating mental illness which has a significant genetic component. The identification of genetic factors related to SCZ has been challenging and these factors remain largely unknown. To evaluate the contribution o
Externí odkaz:
https://doaj.org/article/64361a017d1d41eb8033734ff0470ebd
DPYSL2/CRMP2is a microtubule-stabilizing protein crucial for neurogenesis and associated with numerous psychiatric and neurodegenerative disorders.DPYSL2has multiple RNA and protein isoforms, but few studies have differentiated between them or explor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::497c5745ca2fd25e9b80d8a16903397a
https://doi.org/10.1101/2022.11.19.517191
https://doi.org/10.1101/2022.11.19.517191
Autor:
Hillary Protas, Dimitri Avramopoulos, Kewei Chen, Eric M. Reiman, Gwenn S. Smith, Jin Hui Joo, Alena Savonenko, Yi Su, Neda F Gould, Ayon Nandi, Hiroto Kuwabara, Clifford I. Workman, Michael A. Kraut
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Depression in late-life is associated with increased risk of cognitive decline and development of all-cause dementia. The neurobiology of late-life depression (LLD) may involve both neurochemical and neurodegenerative mechanisms that are common to de
Epigenetics in Psychiatry, Second Edition covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cogni
Autor:
Deborah A. Nickerson, Pengfei Liu, Nara Sobreira, Jessica X. Chong, Eric Boerwinkle, Davut Pehlivan, Samantha Baxter, Nan Wu, V. Reid Sutton, David Valle, Jill A. Rosenfeld, Dimitri Avramopoulos, Tamar Harel, Anne H. O’Donnell-Luria, Murat Gunel, Jennifer E. Posey, Tara C. Matise, Richard P. Lifton, James R. Lupski, Heidi L. Rehm, Donna M. Muzny, Claudia M.B. Carvalho, Steven Buyske, Zeynep Coban Akdemir, Daniel G. MacArthur, C. D. Boehm, Mark Gerstein, Kimberly F. Doheny, Janson White, Richard A. Gibbs, Sushant Kumar, Shalini N. Jhangiani, Michael J. Bamshad, Shrikant Mane, P. Dane Witmer, Ada Hamosh
Identifying genes and variants contributing to rare disease phenotypes and Mendelian conditions informs biology and medicine, yet potential phenotypic consequences for variation of >75% of the ~20,000 annotated genes in the human genome are lacking.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d520799dffb7cfa41be7ecb5193816e3
https://europepmc.org/articles/PMC6691975/
https://europepmc.org/articles/PMC6691975/
Autor:
David S. Thylur, Jennifer G. Mulle, Ann E. Pulver, Karen N. Conneely, Brad D. Pearce, Dimitri Avramopoulos, Adriana Lori, Fernando S. Goes
Publikováno v:
Schizophrenia Bulletin
Background Exposure to Toxoplasma gondii (TOXO) has been consistently associated with the development of schizophrenia, but the neurobiological mechanism through which this occurs is not well elucidated. Emerging data has broadly implicated the adapt