Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Dimitra Thomaidou"'
Autor:
Elsa Papadimitriou, Dimitra Thomaidou
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 9, Pp 1929-1939 (2024)
Neurogenesis is a tightly regulated process in time and space both in the developing embryo and in adult neurogenic niches. A drastic change in the transcriptome and proteome of radial glial cells or neural stem cells towards the neuronal state is ac
Externí odkaz:
https://doaj.org/article/0e1ee622baa04689811b9f8be9130fdd
Autor:
Evangelia Xingi, Paraskevi N. Koutsoudaki, Irini Thanou, Minh-Son Phan, Maria Margariti, Anja Scheller, Jean-Yves Tinevez, Frank Kirchhoff, Dimitra Thomaidou
Publikováno v:
Cells, Vol 12, Iss 10, p 1418 (2023)
The Neurovascular Unit (NVU), composed of glia (astrocytes, oligodendrocytes, microglia), neurons, pericytes and endothelial cells, is a dynamic interface ensuring the physiological functioning of the central nervous system (CNS), which gets affected
Externí odkaz:
https://doaj.org/article/81f10eed7d9444e49d62446a2137aa91
Autor:
Ilianna Zoi, Michalis V. Karamouzis, Evangelia Xingi, Panagiotis Sarantis, Dimitra Thomaidou, Panayiotis Lembessis, Stamatios Theocharis, Athanasios G. Papavassiliou
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-16 (2019)
Abstract Background ERBB-2 is overexpressed in about 20% of breast cancers (BCs), indicating poor prognosis. The receptor activator of nuclear factor-κB (RANK) pathway is implicated in ERBB-2 (+) BC. The purpose of this study was to elucidate the un
Externí odkaz:
https://doaj.org/article/9cf8a3ec7bf3431e92081a5db160d475
Autor:
Ilias Roufagalas, Maria Avloniti, Alexandra Fortosi, Evangelia Xingi, Dimitra Thomaidou, Lesley Probert, Vasiliki Kyrargyri
Publikováno v:
Neurobiology of Disease, Vol 157, Iss , Pp 105449- (2021)
Microglia are key players in Multiple Sclerosis (MS), expressing many susceptibility genes for this disease. They constantly survey the brain microenvironment, but the precise functional relationships between microglia and pathological processes rema
Externí odkaz:
https://doaj.org/article/4942f21d41f64628929d2760d9a96963
Autor:
Yassemi Koutmani, Ioannis A. Gampierakis, Alexia Polissidis, Methodios Ximerakis, Paraskevi N. Koutsoudaki, Alexandros Polyzos, George Agrogiannis, Sevasti Karaliota, Dimitra Thomaidou, Lee L. Rubin, Panagiotis K. Politis, Katia P. Karalis
Publikováno v:
Cell Reports, Vol 29, Iss 4, Pp 932-945.e7 (2019)
Summary: Local cues in the adult neurogenic niches dynamically regulate homeostasis in neural stem cells, whereas their identity and associated molecular mechanisms remain poorly understood. Here, we show that corticotropin-releasing hormone (CRH), t
Externí odkaz:
https://doaj.org/article/4c2927ca07724a1996222ea2435ef2cb
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Huntington’s Disease (HD) is a neurodegenerative disorder caused by a CAG expansion in the exon-1 of the IT15 gene encoding the protein Huntingtin. Expression of mutated Huntingtin in humans leads to dysfunction and ultimately degeneration of selec
Externí odkaz:
https://doaj.org/article/3f51ff8724c14a06b6f4cc60e87e7e5f
Autor:
Katerina Aravantinou-Fatorou, Felipe Ortega, Dafni Chroni-Tzartou, Nasia Antoniou, Cornelia Poulopoulou, Panagiotis K. Politis, Benedikt Berninger, Rebecca Matsas, Dimitra Thomaidou
Publikováno v:
Stem Cell Reports, Vol 5, Iss 3, Pp 405-418 (2015)
Recent studies demonstrate that astroglia from non-neurogenic brain regions can be reprogrammed into functional neurons through forced expression of neurogenic factors. Here we explored the effect of CEND1 and NEUROG2 on reprogramming of mouse cortic
Externí odkaz:
https://doaj.org/article/adc94e0bc89e4496a5f98c1d5f1282ef
Publikováno v:
The International Journal of Developmental Biology. 66:199-209
Direct reprogramming of glial cells into induced-neurons is a promising strategy for CNS repair after acute injury or neurodegenerative diseases. Grey matter astrocytes, which exhibit features of neural stem cells when activated, are an ideal cell so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e604e8cf04273aabc92c63f524bd58f
https://doi.org/10.1387/ijdb.210148dt
https://doi.org/10.1387/ijdb.210148dt
Autor:
Dimitra Thomaidou, Alexandra Fortosi, Evangelia Xingi, Ilias Roufagalas, Maria Avloniti, Vasiliki Kyrargyri, Lesley Probert
Publikováno v:
Neurobiology of Disease, Vol 157, Iss, Pp 105449-(2021)
Microglia are key players in Multiple Sclerosis (MS), expressing many susceptibility genes for this disease. They constantly survey the brain microenvironment, but the precise functional relationships between microglia and pathological processes rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84833e08b4bd8b8caa7e745a451e6d6
https://pubmed.ncbi.nlm.nih.gov/34274460
https://pubmed.ncbi.nlm.nih.gov/34274460
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2155
Direct neuronal reprogramming, rewiring the epigenetic and transcriptional network of a differentiated cell type to neuron, apart from being a very promising approach for the treatment of brain injury and neurodegeneration, also offers a prime opport
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95b28caae146370e1c44850eb8aa3e26
https://pubmed.ncbi.nlm.nih.gov/32474866
https://pubmed.ncbi.nlm.nih.gov/32474866