Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Dimithree Kahanda"'
Autor:
Reema McMullen, Colton L. Starcher, Edward A. Motea, Zakari Ishak-Boushaki, Chloe C. DiTusa, Dimithree Kahanda, Naveen Singh, Jason D. Slinker, Ashan P. Wettasinghe
Publikováno v:
ACS Sens
Here, we utilize electrochemical DNA devices to quantify and understand the cancer-specific DNA-damaging activity of an emerging drug in cellular lysates at femtomolar and attomolar concentrations. Isobutyl-deoxynyboquinone (IB-DNQ), a potent and tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c8d2152cd5911b1f7d6e648167d019d
https://pubmed.ncbi.nlm.nih.gov/34156840
https://pubmed.ncbi.nlm.nih.gov/34156840
Autor:
Chia-Ping Tseng, Dimithree Kahanda, Joshua T. Atkinson, Jinyoung Kim, Jonathan J. Silberg, George N. Bennett, Rafael Verduzco, Othneil N. Sparks, Ian J. Campbell
Publikováno v:
ACS synthetic biology. 9(12)
Homologous recombination can be used to create enzymes that exhibit distinct activities and stabilities from proteins in nature, allowing researchers to overcome component limitations in synthetic biology. To investigate how recombination affects the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7939a3655a94c2809f990ad781c3ae2
https://pubmed.ncbi.nlm.nih.gov/33226772
https://pubmed.ncbi.nlm.nih.gov/33226772
Autor:
Weijun Xu, Othneil N. Sparks, Jonathan J. Silberg, George N. Bennett, Mitchell D. Miller, Ian J. Campbell, Dimithree Kahanda, Joshua T. Atkinson, Jose L. Olmos, George N. Phillips
Publikováno v:
J Biol Chem
Marine cyanobacteria are infected by phages whose genomes encode ferredoxin (Fd) electron carriers. These Fds are thought to redirect the energy harvested from light to phage-encoded oxidoreductases that enhance viral fitness, but it is unclear how t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d0afb37d4349ccbb4096c9be1bf330
https://europepmc.org/articles/PMC7397100/
https://europepmc.org/articles/PMC7397100/
Autor:
Dimithree Kahanda, George N. Phillips, George N. Bennett, Jose L. Olmos, Othneil N. Sparks, Joshua T. Atkinson, Jonathan J. Silberg, Weijun Xu, Mitchell D. Miller, Ian J. Campbell
Marine cyanobacteria are infected by phage whose genomes encode ferredoxin (Fd) electron carriers. While these Fds are thought to redirect the energy harvested from light to phage-encoded oxidoreductases that enhance viral fitness, it is not clear ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15f2a7676dca845f04ee223be0dd94a3
https://doi.org/10.1101/2020.02.07.937771
https://doi.org/10.1101/2020.02.07.937771
Publikováno v:
Biosensors and Bioelectronics. 119:1-9
There is a great need to track the selectivity of anticancer drug activity and to understand the mechanisms of associated biological activity. Here we focus our studies on the specific NQO1 bioactivatable drug, s-lapachone, which is in several Phase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510eb227547528459cfaaa730248a567
https://doi.org/10.1016/j.bios.2018.07.059
https://doi.org/10.1016/j.bios.2018.07.059
One challenge with controlling electron flow in cells is the lack of biomolecules that directly couple the sensing of environmental conditions to electron transfer efficiency. To overcome this protein component limitation, we randomly inserted the li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206de1bc32b0b53eeffcc99b161f483c
https://doi.org/10.1101/645978
https://doi.org/10.1101/645978
Autor:
Jason D. Slinker, Dimithree Kahanda, David A. Boothman, Marc A. McWilliams, Gaurab Chakrabarti
Publikováno v:
Biosensors and Bioelectronics. 80:647-653
It is beneficial to develop systems that reproduce complex reactions of biological systems while maintaining control over specific factors involved in such processes. We demonstrated a DNA device for following the repair of DNA damage produced by a r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa9f551068a66f3e36d5145deba3b001
https://doi.org/10.1016/j.bios.2016.02.026
https://doi.org/10.1016/j.bios.2016.02.026
Autor:
Marc A. McWilliams, Jason D. Slinker, Li Fan, Chris Wohlgamuth, Eduardo Hilario, Kevin DuPrez, Dimithree Kahanda
Publikováno v:
Analytical chemistry, vol 90, iss 3
Much remains to be understood about the kinetics and thermodynamics of DNA helicase binding and activity. Here, we utilize probe-modified DNA monolayers on multiplexed gold electrodes as a sensitive recognition element and morphologically responsive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0866689818e72741933187da877e3e89
https://escholarship.org/uc/item/81m756wq
https://escholarship.org/uc/item/81m756wq