Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Dimethandrolone-undecanoate"'
Autor:
Rachelle Bross, Jill Long, Ronald S. Swerdloff, Laura Hull, Arthi Thirumalai, Diana L. Blithe, Peter Liu, Frances A Fernando, Stephanie T. Page, Christina Wang, Youngju Pak, Fiona Yuen
Publikováno v:
Andrology
Background Dimethandrolone (DMA) and 11β-methyl-19-nortestosterone (11β-MNT) are two novel compounds with both androgenic and progestational activity that are under investigation as potential male hormonal contraceptives. Their metabolic effects ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0322986d0d5b62bb84fecdfcce05ba35
https://doi.org/10.1111/andr.13025
https://doi.org/10.1111/andr.13025
Publikováno v:
J Clin Endocrinol Metab
BackgroundThe advent of new methods of male contraception would increase contraceptive options for men and women and advance male contraceptive agency. Pharmaceutical R&D for male contraception has been dormant since the 1990s. The Eunice Kennedy Shr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d58321b277a85cd84ca387e86c0f2b1d
https://doi.org/10.1210/clinem/dgab034
https://doi.org/10.1210/clinem/dgab034
Autor:
John K. Amory, Stephanie T. Page, Peter Liu, Arthi Thirumalai, Ronald S. Swerdloff, Jill Long, Fiona Yuen, Andrew N. Hoofnagle, Christina Wang, Diana L. Blithe
Publikováno v:
J Clin Endocrinol Metab
Context Dimethandrolone undecanoate (DMAU) is being developed as a male contraceptive. Daily oral administration of DMAU, a potent androgen that is not aromatized, markedly suppresses serum testosterone (T) and estradiol (E2) in healthy men. E2 defic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5248f0689530abf4c49420a1d1c993ea
https://doi.org/10.1210/clinem/dgaa761
https://doi.org/10.1210/clinem/dgaa761
Autor:
Theodore Danoff, Ronald S. Swerdloff, F. Bai, Jonas Čeponis, Andrew Leung, James Longstreth, Robert E Dudley, Laura Hull, Christina Wang
Publikováno v:
Andrology
Background Ex vivo androgen prodrug conversion by blood esterases after oral androgen ester administration may result in an overestimation of the measured blood androgens. Objective We investigated whether blood collection tubes with esterase inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d9b1583a2ab74e4e44f6b909c5d3a4
http://europepmc.org/articles/PMC6519384
http://europepmc.org/articles/PMC6519384
Publikováno v:
Clinical Chemistry. 65:153-160
BACKGROUNDDevelopment of new methods of male contraception would address an unmet need for men to control their fertility and could increase contraceptive options for women. Pharmaceutical research and development for male contraception was active in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::109c8c7c6bea766a87e2559568e50047
https://doi.org/10.1373/clinchem.2018.295089
https://doi.org/10.1373/clinchem.2018.295089
Akademický článek
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Autor:
Arthi Thirumalai, John K. Amory
Publikováno v:
Fertil Steril
Despite significant interests in contraception by men, effective methods of male contraception are limited to vasectomy and condoms. Recently, there have been several promising advances in male contraceptive research. This review will update readers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc30c8a46a4e2d90a800f378dd6e2db
https://pubmed.ncbi.nlm.nih.gov/33931201
https://pubmed.ncbi.nlm.nih.gov/33931201
В данной статье обобщены данные различных видах гормональной мужской контрацепции. Авторами проведено сравнение методов доставки преп
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16bd262db7e56ad341e23cdf362f1c84
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Jing H. Chao, A. Christy, Peter Liu, R. Ayoub, Diana L. Blithe, William J. Bremner, Stephanie T. Page, John K. Amory, Christina Wang, Andrew Leung, Ronald S. Swerdloff, Laura Hull
Publikováno v:
Andrology. 5:278-285
Dimethandrolone (DMA, 7α,11β-dimethyl-19-nortestosterone) has both androgenic and progestational activities, ideal properties for a male hormonal contraceptive. In vivo, dimethandrolone undecanoate (DMAU) is hydrolyzed to DMA. We showed previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f87c97339184417fc4185b27b9bbd646
https://doi.org/10.1111/andr.12303
https://doi.org/10.1111/andr.12303