Výsledky vyhledávání - "Dima Ghannoum"

Akademický článek

Xylosyltransferase I mediates the synthesis of proteoglycans with long glycosaminoglycan chains and controls chondrocyte hypertrophy and collagen fibers organization of in the growth plate

Autor: Mahdia Taieb, Dima Ghannoum, Lydia Barré, Mohamed Ouzzine

Publikováno v: Cell Death and Disease, Vol 14, Iss 6, Pp 1-13 (2023)

Abstract Genetic mutations in the Xylt1 gene are associated with Desbuquois dysplasia type II syndrome characterized by sever prenatal and postnatal short stature. However, the specific role of XylT-I in the growth plate is not completely understood.

Externí odkaz: https://doaj.org/article/7987f4b4c8084bb0b3875fe18b962f37

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A new perfusion mode of culture for WJ‐MSCs expansion in a stirred and online monitored bioreactor

Autor: Bruno Ebel, Emmanuel Guedon, Fanny Gallo, Eric Olmos, Caroline Sion, Natalia de Isla, Dima Ghannoum, Isabelle Chevalot

Publikováno v: Biotechnology and Bioengineering
Biotechnology and Bioengineering, Wiley, 2021, 118 (11), pp.4453-4464. ⟨10.1002/bit.27914⟩

Since a clinical dose requires a minimum of 106 cells per kilogram of patients, it is therefore crucial to develop a scalable method of production of Wharton Jelly Mesenchymal stem cells (WJ-MSCs) with maintained inner characteristics. Scalable expan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3497e58691b365e936e046d119eea813
https://hal.archives-ouvertes.fr/hal-03505287

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