Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Dilson E Rassier"'
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0121726 (2015)
Length changes of muscle fibers have previously been shown to result in a temporary reduction in fiber stiffness that is referred to as thixotropy. Understanding the mechanism of this thixotropy is important to our understanding of muscle function si
Externí odkaz:
https://doaj.org/article/7504034dcebc4810935980b9c63701b8
Autor:
Fabio C Minozzo, Dilson E Rassier
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68866 (2013)
The goal of this study was to compare the effects of Ca(2+) and MgADP activation on force development in skeletal muscles during and after imposed length changes. Single fibres dissected from the rabbit psoas were (i) activated in pCa(2+)4.5 and pCa(
Externí odkaz:
https://doaj.org/article/ac8cac7058d0403f89730d138f298747
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29356 (2012)
When skeletal muscles are activated and mechanically shortened, the force that is produced by the muscle fibers decreases in two phases, marked by two changes in slope (P₁ and P₂) that happen at specific lengths (L₁ and L₂). We tested the hyp
Externí odkaz:
https://doaj.org/article/394d80a9e6af4f1ba7bc1154fce139f6
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Release of the ATP hydrolysis product orthophosphate (Pi) from the myosin active site is central in force generation but is poorly understood. Here, Moretto et al. present evidence for multistep Pi-release reconciling apparently contradictory results
Externí odkaz:
https://doaj.org/article/7192ea2e91f44302a27283b4a6501efa
Autor:
Paulo S. Pedrazzani, Tatiana O. P. Araújo, Emilly Sigoli, Isabella R. da Silva, Daiane Leite da Roza, Deise Lucia Chesca, Dilson E. Rassier, Anabelle S. Cornachione
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Duchene muscular dystrophy (DMD) is caused by the absence of the protein dystrophin, which leads to muscle weakness, progressive degeneration, and eventually death due to respiratory failure. Low-intensity eccentric training (LIET) has been
Externí odkaz:
https://doaj.org/article/c24fc3a80e7f4053b5a2b501df4c33fa
Autor:
Ricarda M. Haeger, Dilson E. Rassier
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Abstract When a muscle is stretched during a contraction, the resulting steady-state force is higher than the isometric force produced at a comparable sarcomere length. This phenomenon, also referred to as residual force enhancement, cannot be readil
Externí odkaz:
https://doaj.org/article/577b09f49ddf4df1ad8556ae2f6d7ab7
Autor:
Alf Månsson, Dilson E. Rassier
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12084 (2022)
Bottom-up mechanokinetic models predict ensemble function of actin and myosin based on parameter values derived from studies using isolated proteins. To be generally useful, e.g., to analyze disease effects, such models must also be able to predict e
Externí odkaz:
https://doaj.org/article/e12da89fef2947bcafe862e12c69d45e
Autor:
Feng Liang, Guillaume Emeriaud, Dilson E. Rassier, Dong Shang, Ekaterina Gusev, Sabah N. A. Hussain, Michael Sage, Benjamin Crulli, Etienne Fortin-Pellerin, Jean-Paul Praud, Basil J. Petrof
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-10 (2019)
Abstract Background Diaphragm weakness occurs rapidly in adult animals treated with mechanical ventilation (MV), but the effects of MV on the neonatal diaphragm have not been determined. Furthermore, it is unknown whether co-existent lung disease exa
Externí odkaz:
https://doaj.org/article/936b198f33944622bcd44ba3a219c342
Autor:
Enrico Pierantozzi, Péter Szentesi, Cecilia Paolini, Beatrix Dienes, János Fodor, Tamás Oláh, Barbara Colombini, Dilson E. Rassier, Egidio Maria Rubino, Stephan Lange, Daniela Rossi, László Csernoch, Maria Angela Bagni, Carlo Reggiani, Vincenzo Sorrentino
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1319 (2022)
Obscurin is a giant sarcomeric protein expressed in striated muscles known to establish several interactions with other proteins of the sarcomere, but also with proteins of the sarcoplasmic reticulum and costameres. Here, we report experiments aiming
Externí odkaz:
https://doaj.org/article/f90b0f4dbf77435398a6de274560e28c
Autor:
Alf Månsson, Marko Usaj, Luisa Moretto, Oleg Matusovsky, Lok Priya Velayuthan, Ran Friedman, Dilson E Rassier
Release of the ATP hydrolysis product inorganic phosphate (Pi) from the active site of myosin is central in chemo-mechanical energy transduction and closely associated with the main force-generating structural change, the power-stroke. Despite intens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebdb24c5b9860b4e25509196daa52b2c
https://doi.org/10.1101/2023.04.12.535196
https://doi.org/10.1101/2023.04.12.535196