Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Dilniya Fattah"'
Autor:
Angela Deakin, Graham Duddy, Steve Wilson, Steve Harrison, Judi Latcham, Mick Fulleylove, Sylvia Fung, Jason Smith, Mike Pedrick, Tom McKevitt, Leigh Felton, Joanne Morley, Diana Quint, Dilniya Fattah, Brian Hayes, Jade Gough, Roberto Solari
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107490 (2014)
Interleukin-2 inducible tyrosine kinase (ITK) is expressed in T cells and plays a critical role in signalling through the T cell receptor. Evidence, mainly from knockout mice, has suggested that ITK plays a particularly important function in Th2 cell
Externí odkaz:
https://doaj.org/article/d1d949c2f0704f36a96334e7c5b4b83c
Autor:
Dilniya Fattah, Bita Manzouri, Santa Jeremy Ono, Masaharu Ohbayashi, Andrea Leonardi, Daniel F P Larkin
Publikováno v:
British Journal of Ophthalmology. 94:1662-1667
Background Dendritic cells (DCs) are the most potent antigen-presenting cells involved in initiating the immune response, presenting antigens to T cells and leading to T cell proliferation. In an immature state, DCs lack accessory signals required fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442796964e36b78ac5cbe48990f2a8db
https://doi.org/10.1136/bjo.2009.177774
https://doi.org/10.1136/bjo.2009.177774
Autor:
Jason C. Smith, Mike Pedrick, Tom McKevitt, Steve Wilson, Joanne Morley, Sylvia Fung, Angela M. Deakin, Leigh M. Felton, Graham Duddy, Steve Mark Harrison, Roberto Solari, Dilniya Fattah, Judi Latcham, Brian Hayes, Mick Fulleylove, Diana Quint, Jade Gough
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107490 (2014)
PLoS ONE
PLoS ONE
Interleukin-2 inducible tyrosine kinase (ITK) is expressed in T cells and plays a critical role in signalling through the T cell receptor. Evidence, mainly from knockout mice, has suggested that ITK plays a particularly important function in Th2 cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba607147a42e4b5b791af64bb57d72f4
http://europepmc.org/articles/PMC4174519?pdf=render
http://europepmc.org/articles/PMC4174519?pdf=render
Autor:
Pierre Graber, Michael V. Milburn, Alain R. Bernard, Anne M. Hassell, Dilniya Fattah, Amanda E. I. Proudfoot, Steven R. Jordan, Timothy N. C. Wells
Publikováno v:
European Journal of Biochemistry. 212:751-755
Interleukin-5 (IL-5) plays a key role in the proliferation and differentiation of eosinophils. To aid the solution of the crystallographic three-dimensional structure, we have expressed large quantities of recombinant human IL-5 (hIL-5) in a methioni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::710755fb3901e2db5bb0c2054f8152c8
https://doi.org/10.1111/j.1432-1033.1993.tb17714.x
https://doi.org/10.1111/j.1432-1033.1993.tb17714.x
Autor:
Dilniya Fattah, Edward D. Zanders, Brian Robert Champion, Robin O'Malley, Amanda E. I. Proudfoot, Diana Quint
Publikováno v:
Cytokine. 2:112-121
The functional activities of highly purified recombinant human IL 5 (hIL 5) have been characterized on a number of cell types in vitro and in BALB/c mice in vivo. In vitro, hIL 5 could induce the differentiation of eosinophils from precursors in both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8148a67f86d8c6dfb3682d053b5bceb2
https://doi.org/10.1016/1043-4666(90)90005-e
https://doi.org/10.1016/1043-4666(90)90005-e
Autor:
Keith P. Ray, Iain Uings, Dilniya Fattah, Susan J. Smith, Francesca Levi-Schaffer, Vladislav Temkin, Ilaria Puxeddu
Publikováno v:
Clinical and Molecular Allergy, Vol 3, Iss 1, p 5 (2005)
Clinical and molecular allergy : CMA
Clinical and molecular allergy : CMA
SummaryBackgroundTNF-alpha is an important mediator in allergy also for its effects on eosinophils.MethodsThe effect of dexamethasone on TNF-alpha induced eosinophils survival, degranulation (ECP), cytokines release (IL-8, GM-CSF) and adhesion to VCA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eed65c0717f6493e4e9f9d184f341e14
https://doi.org/10.1186/1476-7961-3-5
https://doi.org/10.1186/1476-7961-3-5
Autor:
Timothy N. C. Wells, Kevin Page, Dilniya Fattah, Martyn Banks, Christian Y. Arod, Richard Fish, Iain Uings, Murray McKinnon, Amanda E. I. Proudfoot, Roberto Solari, Pierre Graber
Publikováno v:
The Journal of Experimental Medicine
Interleukin 5 (IL-5) is the key cytokine involved in regulating the production and many of the specialized functions of mature eosinophils including priming, adhesion, and survival. We have generated a point mutant of human IL-5, IL-5 (E12K), which i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c840ff5598a5d505ab29345e8d35f33
https://pubmed.ncbi.nlm.nih.gov/9207003
https://pubmed.ncbi.nlm.nih.gov/9207003
Autor:
Dilniya Fattah, Roberto Solari, Martyn Banks, Pierre Graber, Manuel C. Peitsch, M. Mckinnon, Timothy N. C. Wells, Amanda E. I. Proudfoot
Publikováno v:
Annals of the New York Academy of Sciences. 796
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a94c5ac37f6b2f931ba480edd30de8
https://pubmed.ncbi.nlm.nih.gov/8906230
https://pubmed.ncbi.nlm.nih.gov/8906230
Publikováno v:
American journal of respiratory cell and molecular biology. 14(5)
A murine model of allergen-induced airway inflammation and epithelial phenotypic change, and the time-courses of these events, are described. Mice were sensitized to ovalbumin using an adjuvant-free protocol, and challenged by multiple intratracheal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e045f488de67f3a63138f84a45ddc48
https://pubmed.ncbi.nlm.nih.gov/8624247
https://pubmed.ncbi.nlm.nih.gov/8624247
Autor:
Richard Priest, Supriya Bezbaruah, Roberto Solari, Dilniya Fattah, Kevin Page, Carmel M.T. Horgan
Publikováno v:
Cytokine. 8(3)
Interleukin 5 (IL-5) is a T-cell derived cytokine that induces eosinophil growth and differentiation in both mouse and human bone marrow cultures. Elevated levels of IL-5 as well as eosinophils have been detected in the sputum and Bronchoalveolar lav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5cc9556dd138124970c973c5a3a2e1b
https://pubmed.ncbi.nlm.nih.gov/8833040
https://pubmed.ncbi.nlm.nih.gov/8833040