Rapid Detection and Inhibition of SARS-CoV-2-Spike Mutation-Mediated Microthrombosis

Autor: Satta, Sandro, Lai, Angela, Cavallero, Susana, Williamson, Cayden, Chen, Justin, Blázquez-Medela, Ana M, Roustaei, Mehrdad, Dillon, Barbara J, Ashammakhi, Nureddin, Carlo, Dino Di, Li, Zhaoping, Sun, Ren, Hsiai, Tzung K

Publikováno v: Advanced science (Weinheim, Baden-Wurttemberg, Germany), vol 8, iss 23

Activation of endothelial cells following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is thought to be the primary driver for the increasingly recognized thrombotic complications in coronavirus disease 2019 patients, potent

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Rapid Detection and Inhibition of SARS-CoV-2-Spike Mutation-Mediated Microthrombosis.

Autor: Satta S; Division of Cardiology, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, CA, 90095, USA., Lai A; Division of Cardiology, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, CA, 90095, USA., Cavallero S; Division of Cardiology, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, CA, 90095, USA.; Department of Medicine, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA, 90073, USA., Williamson C; Department of Bioengineering, Henry Samueli School of Engineering & Applied Science, University of California, Los Angeles, CA, 90095, USA., Chen J; Department of Bioengineering, Henry Samueli School of Engineering & Applied Science, University of California, Los Angeles, CA, 90095, USA., Blázquez-Medela AM; Division of Cardiology, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, CA, 90095, USA., Roustaei M; Department of Bioengineering, Henry Samueli School of Engineering & Applied Science, University of California, Los Angeles, CA, 90095, USA., Dillon BJ; Division of Cardiology, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, CA, 90095, USA., Ashammakhi N; Department of Bioengineering, Henry Samueli School of Engineering & Applied Science, University of California, Los Angeles, CA, 90095, USA., Carlo DD; Department of Bioengineering, Henry Samueli School of Engineering & Applied Science, University of California, Los Angeles, CA, 90095, USA., Li Z; Department of Medicine, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA, 90073, USA.; Division of Clinical Nutrition, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, CA, 90095, USA., Sun R; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at University of California, Los Angeles, CA, 90095, USA.; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Hsiai TK; Division of Cardiology, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, CA, 90095, USA.; Department of Medicine, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA, 90073, USA.; Department of Bioengineering, Henry Samueli School of Engineering & Applied Science, University of California, Los Angeles, CA, 90095, USA.

Publikováno v: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2021 Dec; Vol. 8 (23), pp. e2103266. Date of Electronic Publication: 2021 Oct 23.