Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Dilip Worah"'
Autor:
Wenwen Ma, Panayiotis P. Constantinides, Dean R. Kessler, Alex K. Tustian, Karel J. Lambert, Salima Lalji, Dilip Worah, Steven C. Quay, Bryan Wentzel, Brian Schneider
Publikováno v:
Pharmaceutical Research. 17:175-182
Purpose. Paclitaxel is currently administered i.v. as a slow infusion of asolution of the drug in an ethanol:surfactant:saline admixture. However,poor solubilization and toxicity are associated with this drug therapy.Alternative drug delivery systems
Publikováno v:
Magnetic Resonance in Medicine. 22:216-221
At the currently administered clinical doses, paramagnetic metal chelate complexes presently used as MR contrast enhancement agents appear to be relatively nontoxic. Solution thermodynamic, solubility, and selectivity studies, based on a number of ga
Autor:
Steven C. Quay, C J Fretz, G Elizondo, Joseph T. Ferrucci, Yuk-Ming Tsang, Dilip Worah, David D. Stark, Scott M. Rocklage, M C Chen
Publikováno v:
Radiology. 178:73-78
Manganese(II)-N,N'-dipyridoxylethylenediamine-N,N'-diacetate-5,5'-bis (phosphate) (MnDPDP) is a paramagnetic complex designed for use as a hepatobiliary agent. The T1 relaxivity of MnDPDP (2.8 [mmol/L]-1.sec-1 in aqueous solution) was similar to that
Autor:
Ernest S. Harpur, Dilip Worah, Eckart Holtz, Kazuhisa Furuhama, Petter-Arnt Hals, Hisashi Nomura
Publikováno v:
Investigative radiology. 28
In a wide range of preclinical studies of gadodiamide injection (Omniscan, Sanofi Winthrop, New York, NY, and Nycomed AS, Oslo, Norway), the pharmacokinetics of the compound have been delineated and its safety demonstrated. The pharmacokinetic behavi
Publikováno v:
Investigative radiology. 26(11)
Twenty adult male volunteers were studied in an unblinded, ascending-dose study to evaluate the safety, tolerance, and pharmacokinetics of intravenously administered nonionic gadodiamide injection. Dosages administered were 0.05, 0.1, 0.2, and 0.3 mm
Publikováno v:
Magnetic Resonance Imaging. 12:VIII-IX
Magnetic resonance imaging contrast media used to affect the relaxation times of atoms in body tissues undergoing NMR diagnosis are disclosed. Such media comprise (1) a paramagnetic, physiologically compatible complex of (a) a chelant consisting of a
Publikováno v:
Ultrasound in Medicine & Biology. 23:S137
Publikováno v:
Journal of the American Society of Echocardiography. 8:363
Publikováno v:
Journal of the American Society of Echocardiography. 8:363
Publikováno v:
Magnetic Resonance Imaging. 11:II
In a method of imaging body tissue in a patient, comprising administering to the patient an effective amount of a pharmaceutical agent for effecting the relaxation times of atoms in body tissues undergoing NMR diagnosis, whereby image contrast is enh