A real-world pharmacovigilance study of KRAS G12C mutation inhibitors based on the food and drug administration adverse event reporting system

Autor: Lisha Wu, Maosheng Xu, Xueqin Li, Dilinuer Aierken, Jinxiu Yu, Tao Qin

Publikováno v: Frontiers in Pharmacology, Vol 15 (2024)

IntroductionSotorasib and adagrasib have been widely used for the non-small cell lung cancer (NSCLC) patients harboring Kirsten rat sarcoma viral oncogene homolog (KRAS) G12C mutation. It's necessary to assess their safety profiles in the real-world

Externí odkaz: https://doaj.org/article/d7694903bb0243c59db2c1973e58b157

Rat model demonstrates a high risk of tremolite but a low risk of anthophyllite for mesothelial carcinogenesis

Autor: Dilinuer, Aierken, Yasumasa, Okazaki, Shan Hwu, Chew, Akihiro, Sakai, Yue, Wang, Hirotaka, Nagai, Nobuaki, Misawa, Norihiko, Kohyama, Shinya, Toyokuni

Publikováno v: Nagoya Journal of Medical Science

Asbestos was abundantly used in industry during the last century. Currently, asbestos confers a heavy social burden due to an increasing number of patients with malignant mesothelioma (MM), which develops after a long incubation period. Many studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::32af1ec8a1a35de068b3441813cf4b6d
https://pubmed.ncbi.nlm.nih.gov/25130001

[Excessive fluoride increases the expression of osteocalcin in the mouse testis].

Autor: Qin JH; School of Preclinical Medicine, Xinjiang Medical University, Urumqi, Xinjiang 830011, China.; People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang 830011, China., Dilinuer A; School of Preclinical Medicine, Xinjiang Medical University, Urumqi, Xinjiang 830011, China., Saimire S; School of Preclinical Medicine, Xinjiang Medical University, Urumqi, Xinjiang 830011, China., Kalibinuer A; School of Preclinical Medicine, Xinjiang Medical University, Urumqi, Xinjiang 830011, China., Yusufu M; School of Preclinical Medicine, Xinjiang Medical University, Urumqi, Xinjiang 830011, China., Yirizhati A; School of Preclinical Medicine, Xinjiang Medical University, Urumqi, Xinjiang 830011, China., Cui SS; School of Preclinical Medicine, Xinjiang Medical University, Urumqi, Xinjiang 830011, China., Nuersimanguli M; School of Preclinical Medicine, Xinjiang Medical University, Urumqi, Xinjiang 830011, China., Chen WJ; School of Preclinical Medicine, Xinjiang Medical University, Urumqi, Xinjiang 830011, China., Bai SB; School of Preclinical Medicine, Xinjiang Medical University, Urumqi, Xinjiang 830011, China.

Publikováno v: Zhonghua nan ke xue = National journal of andrology [Zhonghua Nan Ke Xue] 2017 Sep; Vol. 23 (9), pp. 782-785.