Development towards a novel screening method for nipecotic acid bioisosteres using molecular imprinted polymers (MIPs) as alternative to in vitro cellular uptake assays.

Autor: Knippenberg N; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 MD, Maastricht, the Netherlands. Electronic address: niels.knippenberg@maastrichtuniversity.nl., Lowdon JW; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 MD, Maastricht, the Netherlands., Frigoli M; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 MD, Maastricht, the Netherlands., Cleij TJ; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 MD, Maastricht, the Netherlands., Eersels K; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 MD, Maastricht, the Netherlands., van Grinsven B; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 MD, Maastricht, the Netherlands., Diliën H; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 MD, Maastricht, the Netherlands.

Publikováno v: Talanta [Talanta] 2024 Oct 01; Vol. 278, pp. 126500. Date of Electronic Publication: 2024 Jul 10.

Electrochemical Detection of Pseudomonas aeruginosa Quorum Sensing Molecule ( S )- N -Butyryl Homoserine Lactone Using Molecularly Imprinted Polymers.

Autor: Frigoli M; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, P.O. Box 616, Maastricht 6200 MD, The Netherlands., Lowdon JW; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, P.O. Box 616, Maastricht 6200 MD, The Netherlands., Donetti N; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, P.O. Box 616, Maastricht 6200 MD, The Netherlands., Crapnell RD; John Dalton Building, Faculty of Science and Engineering, Manchester Metropolitan University, Chester Street, Manchester M1 5GD, U.K., Banks CE; John Dalton Building, Faculty of Science and Engineering, Manchester Metropolitan University, Chester Street, Manchester M1 5GD, U.K., Cleij TJ; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, P.O. Box 616, Maastricht 6200 MD, The Netherlands., Diliën H; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, P.O. Box 616, Maastricht 6200 MD, The Netherlands., Eersels K; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, P.O. Box 616, Maastricht 6200 MD, The Netherlands., van Grinsven B; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, P.O. Box 616, Maastricht 6200 MD, The Netherlands.

Publikováno v: ACS omega [ACS Omega] 2024 Aug 14; Vol. 9 (34), pp. 36411-36420. Date of Electronic Publication: 2024 Aug 14 (Print Publication: 2024).

Still in Search for an EAAT Activator: GT949 Does Not Activate EAAT2, nor EAAT3 in Impedance and Radioligand Uptake Assays.

Autor: van Veggel L; Department of Neuroscience, BIOMED Biomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, 3590 Hasselt, Belgium.; Department of Psychiatry and Neuropsychology, Division of Translational Neuroscience, European Graduate School of Neuroscience, School for Mental Health and Neuroscience, Maastricht University, 6200 Maastricht, The Netherlands.; University MS Center (UMSC), 3900 Hasselt-Pelt, Belgium., Mocking TAM; Leiden Academic Centre for Drug Research (LACDR), Division of Drug Discovery and Safety, Leiden University, 2333 Leiden, The Netherlands., Sijben HJ; Leiden Academic Centre for Drug Research (LACDR), Division of Drug Discovery and Safety, Leiden University, 2333 Leiden, The Netherlands., Liu R; Leiden Academic Centre for Drug Research (LACDR), Division of Drug Discovery and Safety, Leiden University, 2333 Leiden, The Netherlands., Gorostiola González M; Leiden Academic Centre for Drug Research (LACDR), Division of Drug Discovery and Safety, Leiden University, 2333 Leiden, The Netherlands., Dilweg MA; Leiden Academic Centre for Drug Research (LACDR), Division of Drug Discovery and Safety, Leiden University, 2333 Leiden, The Netherlands., Royakkers J; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 Maastricht, The Netherlands., Li A; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, OX3 7BN Oxford, U.K., Kumar V; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, OX3 7BN Oxford, U.K., Dong YY; Nuffield Department of Clinical Neurosciences, Weatherall Institute of Molecular Medicine, University of Oxford, OX3 7BN Oxford, U.K., Bullock A; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, OX3 7BN Oxford, U.K., Sauer DB; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, OX3 7BN Oxford, U.K., Diliën H; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 Maastricht, The Netherlands., van Westen GJP; Leiden Academic Centre for Drug Research (LACDR), Division of Drug Discovery and Safety, Leiden University, 2333 Leiden, The Netherlands., Schreiber R; Section of Psychopharmacology, Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, 6200 Maastricht, The Netherlands., Heitman LH; Leiden Academic Centre for Drug Research (LACDR), Division of Drug Discovery and Safety, Leiden University, 2333 Leiden, The Netherlands.; Oncode Institute, Einsteinweg 55, 2333 Leiden, The Netherlands., Vanmierlo T; Department of Neuroscience, BIOMED Biomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, 3590 Hasselt, Belgium.; Department of Psychiatry and Neuropsychology, Division of Translational Neuroscience, European Graduate School of Neuroscience, School for Mental Health and Neuroscience, Maastricht University, 6200 Maastricht, The Netherlands.; University MS Center (UMSC), 3900 Hasselt-Pelt, Belgium.

Publikováno v: ACS chemical neuroscience [ACS Chem Neurosci] 2024 Apr 03; Vol. 15 (7), pp. 1424-1431. Date of Electronic Publication: 2024 Mar 13.

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Visualizing GABA transporters in vivo: an overview of reported radioligands and future directions.

Autor: Knippenberg N; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 MD, Maastricht, The Netherlands. niels.knippenberg@maastrichtuniversity.nl., Bauwens M; Department of Nuclear Medicine, University Hospital Aachen, RWTH Aachen University, 52074, Aachen, Germany.; Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre+ (MUMC+), 6229 HX, Maastricht, The Netherlands., Schijns O; Department of Neurosurgery, Maastricht University Medical Centre+ (MUMC+), 6229 HX, Maastricht, The Netherlands.; School for Mental Health and Neuroscience (MHeNS), Maastricht University, 6200 MD, Maastricht, The Netherlands.; Academic Center for Epileptology (ACE), Maastricht University Medical Centre+ (MUMC+), 6229 HX, Maastricht, The Netherlands., Hoogland G; Department of Neurosurgery, Maastricht University Medical Centre+ (MUMC+), 6229 HX, Maastricht, The Netherlands.; School for Mental Health and Neuroscience (MHeNS), Maastricht University, 6200 MD, Maastricht, The Netherlands., Florea A; Department of Nuclear Medicine, University Hospital Aachen, RWTH Aachen University, 52074, Aachen, Germany.; Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre+ (MUMC+), 6229 HX, Maastricht, The Netherlands.; School for Cardiovascular Diseases (CARIM), Maastricht University Medical Centre+ (MUMC+), 6229 HX, Maastricht, The Netherlands., Rijkers K; Department of Neurosurgery, Maastricht University Medical Centre+ (MUMC+), 6229 HX, Maastricht, The Netherlands.; School for Mental Health and Neuroscience (MHeNS), Maastricht University, 6200 MD, Maastricht, The Netherlands.; Academic Center for Epileptology (ACE), Maastricht University Medical Centre+ (MUMC+), 6229 HX, Maastricht, The Netherlands., Cleij TJ; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 MD, Maastricht, The Netherlands., Eersels K; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 MD, Maastricht, The Netherlands., van Grinsven B; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 MD, Maastricht, The Netherlands., Diliën H; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 MD, Maastricht, The Netherlands.

Publikováno v: EJNMMI research [EJNMMI Res] 2023 May 12; Vol. 13 (1), pp. 42. Date of Electronic Publication: 2023 May 12.