Both Pancreatic Cancer and Pancreatic Stellate Cells Express High Levels of Gamma-glutamyl Transferase That May Be Employed to Deliver a Metabolism Inhibitor to the Tumour Mass

Autor: Decollogne, S, Ramsay, Ee, Joshi, S, Corti, Alessandro, Pompella, Alfonso, Apte, M, Hogg, Pj, Dilda, Pj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3728::2440dca0c583d99ca72579ea1a745f17
http://hdl.handle.net/11568/238375

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RAR Inhibitors Display Photo-Protective and Anti-Inflammatory Effects in A2E Stimulated RPE Cells In Vitro through Non-Specific Modulation of PPAR or RXR Transactivation.

Autor: Fontaine V; Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France., Boumedine T; Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France., Monteiro E; Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France., Fournié M; Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France., Gersende G; Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France., Sahel JA; Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.; Fondation Ophtalmologique Rothschild, 29 rue Manin, 75019 Paris, France.; Department of Ophthalmology, The University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Picaud S; Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France., Veillet S; Biophytis, Sorbonne Université, BC9, 4 place Jussieu, 75005 Paris, France., Lafont R; Biophytis, Sorbonne Université, BC9, 4 place Jussieu, 75005 Paris, France., Latil M; Biophytis, Sorbonne Université, BC9, 4 place Jussieu, 75005 Paris, France., Dilda PJ; Biophytis, Sorbonne Université, BC9, 4 place Jussieu, 75005 Paris, France., Camelo S; Biophytis, Sorbonne Université, BC9, 4 place Jussieu, 75005 Paris, France.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 06; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 06.

Efficacy of oral 20-hydroxyecdysone (BIO101), a MAS receptor activator, in adults with severe COVID-19 (COVA): a randomized, placebo-controlled, phase 2/3 trial.

Autor: Lobo SM; Intensive Care Division. Faculdade de Medicina de São José do Rio Preto, São Paulo, Brazil., Plantefève G; Intensive Care Unit, Clinical Research Center and CRICS-Triggersep Network, Centre Hospitalier Victor Dupouy, 69 rue du lieutenant-colonel Prudhon, 95100, Argenteuil, France., Nair G; William Beaumont Hospital, 3601 W. 13 Mile Road, Royal Oak, MI, 48073, USA., Joaquim Cavalcante A; CEMEC - Centro Multidisciplinar de Estudos Clínicos, São Bernardo do Campo, São Paulo, Brazil., Franzin de Moraes N; Hospital Municipal de Barueri Dr. Francisco Moran, Barueri, São Paulo, Brazil., Nunes E; Instituto Nacional de Infectologia Evandro Chagas/ Fiocruz, Rio de Janeiro, Brazil., Barnum O; Barnum Medical Research, Inc, 1029 Keyser Ave, Suite H, Natchitoches, LA, 71457, USA., Berdun Stadnik CM; Santa Casa de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil., Lima MP; Hospital e Maternidade Celso Pierro - PUCCAMP, Campinas, São Paulo, Brazil., Lins M; AZ Sint-Maarten Department: Pneumology General Hospital Sint-Maarten, Liersesteenweg 435, 2800, Mechelen, Belgium., Hajjar LA; Instituto do Coração - INCOR, Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo. HC-FMUSP, São Paulo, Brazil., Lipinski C; Abrazo Health, 2000 West Bethany Home Road Phoenix, AZ, 85015, USA., Islam S; Medical College of Georgia, Augusta University, 1120 15th Street, Augusta, GA, 30912, USA., Ramos F; Hospital São Lucas da Pontíficia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, Brazil., Simon T; Instituto Méderi de Pesquisa e Saúde, Passo Fundo, Rio Grande do Sul, Brazil., Martinot JB; CHU-CLU Clinique et maternité Sainte Elisabeth CSME Namur, Department of Pneumology Place Louise Godin 15, Namur, 5000, Belgium., Guimard T; Centre Hospitalier Départemental de Vendée, Les Oudairies 85925 La Roche-sur-Yon cedex 9, France., Desclaux A; Le Tripode, Groupe hospitalier Pellegrin, Place Amélie Raba-Léon 33000 Bordeaux CHU Bordeaux, France., Lioger B; Service de médecine Interne et Polyvalente, Centre Hospitalier de Blois, Mail Pierre Charlot 41016 Blois CEDEX, France., Neuenschwander FC; Hospital Vera Cruz, Belo Horizonte, Minas Gerais, Brazil., DeSouza Paolino B; Hospital São Lucas SA, Rio de Janeiro, Brazil., Amin A; University of California, Irvine 333 City Blvd West, Suite 500 Orange, CA, 92868, USA., Acosta SA; Manati Medical Center Calle Hernandez Carrion, No. 668 Urb. Atenas Manati, PR, 00674, USA., Dilling DF; Loyola University Medical Center, 2160 S. 1st Ave blg 115 suite 253, Maywood, IL 60153, USA., Cartagena E; San Juan Bautista School of Medicine Clinical Research Unit/ Hospital Menonita Caguas, PR, 00725, USA., Snyder B; Catholic Health System, 2605 Harlem Road, Cheektowaga, NY, 14225, USA., Devaud E; Centre hospitalier René Dubos, Bâtiment A, 6 avenue de l'Ile de France, Cergy Pontoise, 95300, France., Barreto Berselli Marinho AK; Conjunto Hospitalar do Mandaqui, São Paulo, Brazil., Tanni S; UPECLIN - Unidade de Pesquisa Clínica da Faculdade de Medicina de Botucatu - UNESP, Botucatu, São Paulo, Brazil., Milhomem Beato PM; Fundação Doutor Amaral Carvalho - Hospital Amaral, Jau, São Paulo, Brazil., De Wit S; CHU Saint-Pierre, 105, rue aux Laines, Brussels, 1000, Belgium., Selvan V; Texas Tech University Health Sciences Center, Department of Family and Community Medicine, 701 W 5th Street, Odessa, TX, 79763, USA., Gray J; United Health Services Hospitals, 33-57 Harrison Street, Johnson City, NY, 13790, USA., Fernandez R; FDI Clinical Research - San Juan City Hospital, 998 Muñoz Rivera Ave, San Juan, PR, 00927, USA., Pourcher V; Service des Maladies Infectieuses et Tropicales, Groupe Hospitalier Pitié Salpêtrière-Charles Foix, 47-83 Boulevard de l'Hôpital, Paris Cedex 13, 75651, France., Maddox L; WellSpan York Hospital, 101 Shouth George Street, York, 17403, USA., Kay R; RK Statistics Ltd, Brook House, Mesne Lane, Bakewell, DE45 1AL, UK., Azbekyan A; Biophytis - Sorbonne Université, BC9, 4 place Jussieu, 75005, Paris, France., Chabane M; Biophytis - Sorbonne Université, BC9, 4 place Jussieu, 75005, Paris, France., Tourette C; Biophytis - Sorbonne Université, BC9, 4 place Jussieu, 75005, Paris, France., Esmeraldino LE; Biophytis - Sorbonne Université, BC9, 4 place Jussieu, 75005, Paris, France., Dilda PJ; Biophytis - Sorbonne Université, BC9, 4 place Jussieu, 75005, Paris, France., Lafont R; Biophytis - Sorbonne Université, BC9, 4 place Jussieu, 75005, Paris, France.; Sorbonne Université & CNRS - Institut de Biologie Paris Seine (BIOSIPE), 75005, Paris, France., Mariani J; Biophytis - Sorbonne Université, BC9, 4 place Jussieu, 75005, Paris, France.; Sorbonne Université & CNRS - Institut de Biologie Paris Seine, UMR 8256, 75005 Paris, France., Camelo S; Biophytis - Sorbonne Université, BC9, 4 place Jussieu, 75005, Paris, France., Rabut S; Biophytis - Sorbonne Université, BC9, 4 place Jussieu, 75005, Paris, France., Agus S; Biophytis - Sorbonne Université, BC9, 4 place Jussieu, 75005, Paris, France.; Actual address: Altus Care powered by Oberon Sciences, Israel., Veillet S; Biophytis - Sorbonne Université, BC9, 4 place Jussieu, 75005, Paris, France., Dioh W; Biophytis - Sorbonne Université, BC9, 4 place Jussieu, 75005, Paris, France., van Maanen R; Biophytis - Sorbonne Université, BC9, 4 place Jussieu, 75005, Paris, France., Morelot-Panzini C; Service de Pneumologie, Groupe Hospitalier Pitié Salpêtrière, Sorbonne Université 47-83 Boulevard de l'Hôpital, Paris Cedex 13, 75651, France.

Publikováno v: EClinicalMedicine [EClinicalMedicine] 2024 Jan 03; Vol. 68, pp. 102383. Date of Electronic Publication: 2024 Jan 03 (Print Publication: 2024).

Inhibition of mitochondrial translocase SLC25A5 and histone deacetylation is an effective combination therapy in neuroblastoma.

Autor: Seneviratne JA; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia.; School of Women's & Children's Health, UNSW Sydney, New South Wales, Australia., Carter DR; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia.; School of Women's & Children's Health, UNSW Sydney, New South Wales, Australia.; School of Biomedical Engineering, University of Technology Sydney, New South Wales, Australia., Mittra R; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia., Gifford A; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, New South Wales, Australia., Kim PY; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia., Luo JS; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia.; Department of Paediatrics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China., Mayoh C; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia.; School of Women's & Children's Health, UNSW Sydney, New South Wales, Australia., Salib A; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia.; School of Women's & Children's Health, UNSW Sydney, New South Wales, Australia., Rahmanto AS; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia., Murray J; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia., Cheng NC; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia., Nagy Z; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia., Wang Q; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia., Kleynhans A; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia.; School of Women's & Children's Health, UNSW Sydney, New South Wales, Australia., Tan O; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia., Sutton SK; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia., Xue C; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia., Chung SA; Adult Cancer Program, Lowy Cancer Research Centre, UNSW Sydney, New South Wales, Australia., Zhang Y; Department of Paediatrics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.; Department of Paediatric Oncology, Sun Yat-sen University Cancer Centre, Guangzhou, Guangdong, China., Sun C; Department of Paediatrics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.; Department of Paediatric Oncology, Sun Yat-sen University Cancer Centre, Guangzhou, Guangdong, China., Zhang L; Department of Paediatrics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.; Department of Paediatric Oncology, Sun Yat-sen University Cancer Centre, Guangzhou, Guangdong, China., Haber M; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia., Norris MD; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia.; University of New South Wales, Centre for Childhood Cancer Research, Randwick, New South Wales, Australia., Fletcher JI; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia.; School of Women's & Children's Health, UNSW Sydney, New South Wales, Australia., Liu T; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia.; School of Women's & Children's Health, UNSW Sydney, New South Wales, Australia., Dilda PJ; Adult Cancer Program, Lowy Cancer Research Centre, UNSW Sydney, New South Wales, Australia., Hogg PJ; Australian Cancer Research Foundation (ACRF), Centenary Cancer Research Centre, Charles Perkins Centre, University of Sydney, New South Wales, Australia., Cheung BB; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia.; School of Women's & Children's Health, UNSW Sydney, New South Wales, Australia.; Department of Paediatrics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China., Marshall GM; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Kensington, New South Wales, Australia.; School of Women's & Children's Health, UNSW Sydney, New South Wales, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, New South Wales, Australia.

Publikováno v: International journal of cancer [Int J Cancer] 2023 Apr 01; Vol. 152 (7), pp. 1399-1413. Date of Electronic Publication: 2022 Nov 17.