Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Dilaware Khan"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The Circle of Willis perforation (cWp) mouse model is a key tool in subarachnoid hemorrhage (SAH) research; however, inconsistent bleeding volumes can challenge experimental reliability. To address this issue, we introduced the ROB Scoring S
Externí odkaz:
https://doaj.org/article/9dda0d9e737c4ab1b3317487bb615280
Autor:
Dilaware Khan, Huakang Zhou, Jinliang You, Vera Annika Kaiser, Rajiv K Khajuria, Sajjad Muhammad
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Smoking is the major cause of cardiovascular diseases and cancer. It induces oxidative stress, leading to DNA damage and cellular senescence. Senescent cells increase the expression and release of pro-inflammatory molecules and matrix metall
Externí odkaz:
https://doaj.org/article/50c59c189e184f72b8a88e40cc22deae
Autor:
Huakang Zhou, Dilaware Khan, Sajid Muhammad Hussain, Norbert Gerdes, Carsten Hagenbeck, Majeed Rana, Jan Frederick Cornelius, Sajjad Muhammad
Publikováno v:
Journal of Inflammation, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Background Smoking, alcohol abuse, and hypertension are – among others, potential risk factors for cardiovascular diseases. These risk factors generate oxidative stress and cause oxidative stress-induced DNA damage, resulting in cellular s
Externí odkaz:
https://doaj.org/article/4ea19ca5a96f4f8fb221ce5aa7ab69d5
Autor:
Dilaware Khan, Xuanchen Li, Tomoki Hashimoto, Rokuya Tanikawa, Mika Niemela, Michael Lawton, Sajjad Muhammad
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 3 (2024)
Intracranial aneurysms (IAs) are rare vascular lesions that are more frequently found in women. The pathophysiology behind the formation and growth of IAs is complex. Hence, to date, no single pharmacological option exists to treat them. Animal model
Externí odkaz:
https://doaj.org/article/abda606c57764480a5e6da27fea4f961
Autor:
Huakang Zhou, Xuanchen Li, Majeed Rana, Jan Frederick Cornelius, Dilaware Khan, Sajjad Muhammad
Publikováno v:
Cells, Vol 12, Iss 22, p 2609 (2023)
The cardiovascular risk factors, including smoking, ethanol, and oxidative stress, can induce cellular senescence. The senescent cells increase the expression and release of pro-inflammatory molecules and matrix metalloproteinase (MMPs). These pro-in
Externí odkaz:
https://doaj.org/article/a36474bc46794e6fb8f1f1069cd08257
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14218 (2023)
Intracranial aneurysms (IAs) are abnormal dilations of the cerebral vessels, which pose a persistent threat of cerebral hemorrhage. Inflammation is known to contribute to IA development. The nuclear factor “kappa-light-chain-enhancer” of activate
Externí odkaz:
https://doaj.org/article/2b62627ffdbd47ebb2c62c3200aac1fd
Autor:
Zuhair Hawsawi, Dilaware Khan, Igor Fischer, Jan Frederick Cornelius, Daniel Hänggi, Sajjad Muhammad
Publikováno v:
Frontiers in Human Neuroscience, Vol 16 (2022)
IntroductionSARS-CoV-2 virus infection causes a dysbalanced and severe inflammatory response, including hypercytokinemia and immunodepression. Systemic inflammation triggered by a viral infection can potentially cause vascular damage, which may lead
Externí odkaz:
https://doaj.org/article/64693f2950d64dd2a66227bd4315cebc
Autor:
Huakang Zhou, Dilaware Khan, Norbert Gerdes, Carsten Hagenbeck, Majeed Rana, Jan Frederick Cornelius, Sajjad Muhammad
Publikováno v:
Antioxidants, Vol 12, Iss 4, p 960 (2023)
Inflammaging is a potential risk factor for cardiovascular diseases. It results in the development of thrombosis and atherosclerosis. The accumulation of senescent cells in vessels causes vascular inflammaging and contributes to plaque formation and
Externí odkaz:
https://doaj.org/article/5b7652c2675545558b7ed0cf151d86e9
Publikováno v:
Antioxidants, Vol 11, Iss 12, p 2413 (2022)
Excess alcohol consumption is a potential risk factor for cardiovascular diseases and is linked to accelerated aging. Drug discovery to reduce toxic cellular events of alcohol is required. Here, we investigated the effects of ethanol on human umbilic
Externí odkaz:
https://doaj.org/article/17709a82c0724cb49bd0872434864310
Autor:
Dilaware Khan, Soheil Naderi, Mostafa Ahmadi, Askar Ghorbani, Jan Frederick Cornelius, Daniel Hänggi, Sajjad Muhammad
Publikováno v:
Pathogens, Vol 11, Iss 6, p 617 (2022)
Background: SARS-CoV virus infection results in a dysbalanced and severe inflammatory response with hypercytokinemia and immunodepression. Viral infection triggers systemic inflammation and the virus itself can potentially cause vascular damage, incl
Externí odkaz:
https://doaj.org/article/a877e42455c048d191e04cff6e9bdd5d