Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Dilara Sen"'
Publikováno v:
BMC Biotechnology, Vol 21, Iss 1, Pp 1-16 (2021)
Abstract Background Human cerebral organoids (hCO) are attractive systems due to their ability to model important brain regions and transcriptomics of early in vivo brain development. To date, they have been used to understand the effects of genetics
Externí odkaz:
https://doaj.org/article/94a1b449c5894e8195d07c3036bbd70e
Autor:
Sarvenaz Heirani Moghaddam, Dilara Sen, Megan Carson, Robert Mackowiak, Rachel Markley, Gerome Aleandro Manson
Publikováno v:
Brain Sciences, Vol 13, Iss 9, p 1256 (2023)
Previous studies have shown that people with limited motor capabilities may rely on previous motor experience when making action possibility judgments for others. In the present study, we examined if having limited previous motor experience, as a con
Externí odkaz:
https://doaj.org/article/e5af3b106f0b42f9900565ec901fb234
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract UBE3A is an E3 ubiquitin ligase encoded by the neurally imprinted UBE3A gene. The abundance and subcellular distribution of UBE3A has been the topic of many previous studies as its dosage and localization has been linked to neurodevelopmenta
Externí odkaz:
https://doaj.org/article/9e387ac290914899a72d3d48062a092f
Human Cerebral Organoids Reveal Early Spatiotemporal Dynamics and Pharmacological Responses of UBE3A
Publikováno v:
Stem Cell Reports
Summary Angelman syndrome is a complex neurodevelopmental disorder characterized by delayed development, intellectual disability, speech impairment, and ataxia. It results from the loss of UBE3A protein, an E3 ubiquitin ligase, in neurons of the brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d561bb1b87df41dc68bfd4bd8839c8
http://europepmc.org/articles/PMC7561513
http://europepmc.org/articles/PMC7561513
Publikováno v:
BMC Biotechnology
BMC Biotechnology, Vol 21, Iss 1, Pp 1-16 (2021)
BMC Biotechnology, Vol 21, Iss 1, Pp 1-16 (2021)
Background Human cerebral organoids (hCO) are attractive systems due to their ability to model important brain regions and transcriptomics of early in vivo brain development. To date, they have been used to understand the effects of genetics and solu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a355585941a5f5242fe9b752d3976f92
https://doi.org/10.1186/s12896-021-00718-2
https://doi.org/10.1186/s12896-021-00718-2
Autor:
Dilara Sen, Albert J. Keung
Publikováno v:
Curr Opin Biomed Eng
Epigenetic states inherently define a wide range of complex biological phenotypes and processes in development and disease. Accurate cellular modeling would ideally capture the epigenetic complexity of these processes as well as the accompanying mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d89c95ca38f1cc5032e1fcab29dc2d38
https://europepmc.org/articles/PMC7467398/
https://europepmc.org/articles/PMC7467398/
SUMMARYHuman neurodevelopment and its associated diseases are complex and challenging to study. This has driven recent excitement for human cerebral organoids (hCOs) as research and screening tools. These models are steadily proving their utility; ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785cbc2d241f8e503d66b20a72b7cadb
https://doi.org/10.1101/742213
https://doi.org/10.1101/742213
Autor:
Albert J. Keung, Dilara Sen
Publikováno v:
Methods in Molecular Biology ISBN: 9781493977734
The advent of locus-specific protein recruitment technologies has enabled a new class of studies in chromatin biology. Epigenome editors enable biochemical modifications of chromatin at almost any specific endogenous locus. Their locus-specificity un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820ab78f1ebada3f9ea0c4189f31a9a4
https://pubmed.ncbi.nlm.nih.gov/29524129
https://pubmed.ncbi.nlm.nih.gov/29524129
Autor:
Deniz Inal-Ince, Hulya Arikan, Dilara Sen Saklica, Melda Saglam, Ebru Calik-Kutukcu, Naciye Vardar-Yagli
Publikováno v:
Physiotherapists.
Aim: Respiratory function has a vital role in wind instrument playing. However, there is a lack of study investigating respiratory muscle strength and endurance. The purpose of the study was to examine respiratory parameters and exercise capacity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6452facb26b57649cccaacea38f457f
https://doi.org/10.1183/1393003.congress-2017.pa2538
https://doi.org/10.1183/1393003.congress-2017.pa2538