Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Dilani B Senadheera"'
Autor:
Jennifer S Downey, Lauren Mashburn-Warren, Eduardo A Ayala, Dilani B Senadheera, Whitney K Hendrickson, Lathan W McCall, Julie G Sweet, Dennis G Cvitkovitch, Grace A Spatafora, Steven D Goodman
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115975 (2014)
Streptococcus mutans, a major acidogenic component of the dental plaque biofilm, has a key role in caries etiology. Previously, we demonstrated that the VicRK two-component signal transduction system modulates biofilm formation, oxidative stress and
Externí odkaz:
https://doaj.org/article/074321a61e3e469db39631097996633a
Autor:
Eduardo Ayala, Jennifer S Downey, Lauren Mashburn-Warren, Dilani B Senadheera, Dennis G Cvitkovitch, Steven D Goodman
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108027 (2014)
Two-component systems (TCSs) are ubiquitous among bacteria and are among the most elegant and effective sensing systems in nature. They allow for efficient adaptive responses to rapidly changing environmental conditions. In this study, we investigate
Externí odkaz:
https://doaj.org/article/5e16dd152ea54d518a719a17d84f6e40
Autor:
Chen Wang, Jiayan Sang, Jiawei Wang, Mingyan Su, Jennifer S Downey, Qinggan Wu, Shida Wang, Yongfei Cai, Xiaozheng Xu, Jun Wu, Dilani B Senadheera, Dennis G Cvitkovitch, Lin Chen, Steven D Goodman, Aidong Han
Publikováno v:
PLoS Biology, Vol 11, Iss 2, p e1001493 (2013)
Two-component systems (TCSs) are important for the adaptation and survival of bacteria and fungi under stress conditions. A TCS is often composed of a membrane-bound sensor histidine kinase (SK) and a response regulator (RR), which are relayed throug
Externí odkaz:
https://doaj.org/article/2209811eb85f41de96bc1fa2ffe496cb
Autor:
Åsa Nylander, Gunnel Svensäter, Dilani B Senadheera, Dennis G Cvitkovitch, Julia R Davies, Karina Persson
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63768 (2013)
The commensal Streptococcus gordonii expresses numerous surface adhesins with which it interacts with other microorganisms, host cells and salivary proteins to initiate dental plaque formation. However, this Gram-positive bacterium can also spread to
Externí odkaz:
https://doaj.org/article/e0b78bd19c5c4b4d855c8ee6bd8ee93c
Autor:
Michael W Hall, Nimali C Wellappuli, Ruo Chen Huang, Kay Wu, David K Lam, Michael Glogauer, Robert G Beiko, Dilani B Senadheera
AimTo understand the spatiotemporal dynamics of bacterial succession during gingivitis, and to identify taxa with a critical role in gum health with prognostic value.Materials and methodsLongitudinal microbiome data were collected from 15 individuals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78dd1b87ec4b49546ef0ae6b754a631d
https://doi.org/10.1101/2022.08.25.505302
https://doi.org/10.1101/2022.08.25.505302
Autor:
L. Jeannine Brady, Paula J. Crowley, Iwona B. Wenderska, Dennis G. Cvitkovitch, Gursonika Binepal, Dilani B. Senadheera, Richard N. Besingi
Publikováno v:
Microbiology. 163:719-730
Potassium (K(+)) is the most abundant cation in dental plaque fluid. Previously, we reported the link between K(+) transport via Trk2 in Streptococcus mutans and its two critical virulence attributes: acid tolerance and surface adhesion. Herein, we b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4e00d53398a86ad590753a076be68f
https://doi.org/10.1099/mic.0.000458
https://doi.org/10.1099/mic.0.000458
Autor:
Dennis G. Cvitkovitch, Dilani B. Senadheera, Richard N. Besingi, L. Jeannine Brady, Zezhang T. Wen, Joanna R. Long, Iwona B. Wenderska
Publikováno v:
Microbiology. 163:488-501
Amyloids have been identified as functional components of the extracellular matrix of bacterial biofilms. Streptococcus mutans is an established aetiologic agent of dental caries and a biofilm dweller. In addition to the previously identified amyloid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24623d5752d0a3ddee2eb155a712dc15
https://doi.org/10.1099/mic.0.000443
https://doi.org/10.1099/mic.0.000443
Autor:
Naomi Glogauer, Dilani B. Senadheera, Morvarid Oveisi, Michael Glogauer, Noah Fine, Chunxiang Sun, Harold Shifman
Publikováno v:
Infection and Immunity. 87
Neutrophils, the most numerous leukocytes, play an important role in maintaining oral health through interactions with oral microbial biofilms. Both neutrophil hyperactivity and the bacterial subversion of neutrophil responses can cause inflammation-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::739c2462a154184236960d7b8133f002
https://doi.org/10.1128/iai.00790-18
https://doi.org/10.1128/iai.00790-18
Autor:
Dilani B. Senadheera, Kamal Gill, L. Jeannine Brady, Martha Cordova, Paula J. Crowley, Gursonika Binepal, Dennis G. Cvitkovitch
Publikováno v:
Journal of Bacteriology. 198:1087-1100
Potassium (K + ) is the most abundant cation in the fluids of dental biofilm. The biochemical and biophysical functions of K + and a variety of K + transport systems have been studied for most pathogenic bacteria but not for oral pathogens. In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b789f2b95c87bdf6d45e113b1c1e240
https://doi.org/10.1128/jb.00813-15
https://doi.org/10.1128/jb.00813-15
Autor:
Iwona B. Wenderska, Andrew Latos, Benjamin Pruitt, Sara Palmer, Grace Spatafora, Dilani B. Senadheera, Dennis G. Cvitkovitch, Gilles P. van Wezel
Publikováno v:
mSystems, Vol 2, Iss 1 (2017)
mSystems, Vol 2, Iss 1, p e00102-16 (2017)
mSystems, Vol 2, Iss 1, p e00102-16 (2017)
In the cariogenic Streptococcus mutans, competence development is regulated by the ComRS signaling system comprised of the ComR regulator and the ComS prepeptide to the competence signaling peptide XIP (ComX-inducing peptide). Aside from competence d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cdcdd342dc196575a3861ac0c56dfc0
https://journals.asm.org/doi/10.1128/mSystems.00102-16
https://journals.asm.org/doi/10.1128/mSystems.00102-16