Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Dilani A. Jayawardhana"'
Autor:
Xiyun Guan, Dilani A. Jayawardhana, Daniel W. Armstrong, Deqiang Wang, Qitao Zhao, Ranulu Samanthi S. de Zoysa
Publikováno v:
The Journal of Physical Chemistry B. 113:13332-13336
One of the key challenges to nanopore DNA sequencing is to slow down DNA translocation. Here, we report that the translocation velocities of various DNA homo- and copolymers through protein pores could be significantly decreased by using electrolyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e215116d9e702e9d2355daa2b96ec5
https://doi.org/10.1021/jp9040293
https://doi.org/10.1021/jp9040293
Publikováno v:
Biophysical Journal
Salt plays a critical role in the physiological activities of cells. We show that ionic strength significantly affects the kinetics of noncovalent interactions in protein channels, as observed in stochastic studies of the transfer of various analytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ed865c766f68cca2d746a68db6e10b
http://europepmc.org/articles/PMC2212693
http://europepmc.org/articles/PMC2212693
Autor:
Dilani A. Jayawardhana, Xiyun Guan, Mrinal Kumar Sengupta, D. M. Milan Krishantha, Jyoti Gupta, Daniel W. Armstrong
Publikováno v:
Analytical chemistry. 83(20)
The transmembrane protein α-hemolysin pore has been used to develop ultrasensitive biosensors, study biomolecular folding and unfolding, investigate covalent and non-covalent bonding interactions, and probe enzyme kinetics. Here, we report that by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6b1547f0ba7a96c34ebfac52d104e1e
https://pubmed.ncbi.nlm.nih.gov/21919492
https://pubmed.ncbi.nlm.nih.gov/21919492
Publikováno v:
Nanopores ISBN: 9781441982513
Stochastic sensing can detect analytes at the single-molecule level, in which a biological ion channel embedded in a lipid bilayer or a nano-scale sized pore fabricated in a solid-state membrane is used as the sensing element. By monitoring the ionic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7101166fe59b173ab50258557a10dca7
https://doi.org/10.1007/978-1-4419-8252-0_13
https://doi.org/10.1007/978-1-4419-8252-0_13
Publikováno v:
Nanotechnology. 19(50)
In this study, we demonstrate that a pattern-recognition stochastic sensor can be constructed by employing an array of protein pores modified with a variety of non-covalent bonding sites as effective sensing elements. The collective responses of each
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d6ff1f598493fc5431303020040df3c
https://pubmed.ncbi.nlm.nih.gov/19942772
https://pubmed.ncbi.nlm.nih.gov/19942772
Publikováno v:
Analytical chemistry. 81(1)
We report a rapid and sensitive stochastic nanopore sensing method for the detection of monovalent cations and liquid explosive components and their sensitizers. The sensing element is a wild-type alpha-hemolysin protein pore with boromycin as a mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd91761e8fe733ab4bad3f8e4c01428
https://pubmed.ncbi.nlm.nih.gov/19055422
https://pubmed.ncbi.nlm.nih.gov/19055422
Publikováno v:
Journal of the American Chemical Society. 131:6324-6325
Here we report a rapid, label-free method for monitoring peptide cleavage. Monitoring peptide translocation through an engineered ion channel in the absence and the presence of an enzyme allowed quantitative chemical kinetics information on enzymatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d0fe55e54167fb6e7e354a4dc4eba7
https://doi.org/10.1021/ja9004893
https://doi.org/10.1021/ja9004893
Autor:
Ranulu Samanthi S. de Zoysa, Dilani A. Jayawardhana, Qitao Zhao, Deqiang Wang, Daniel W. Armstrong, Xiyun Guan
Publikováno v:
Journal of Physical Chemistry B; Oct2009, Vol. 113 Issue 40, p13332-13336, 5p
Publikováno v:
Journal of Physical Chemistry B; Mar2009, Vol. 113 Issue 11, p3572-3578, 7p
Publikováno v:
Nanotechnology; Dec2008, Vol. 19 Issue 50, p05504-05504, 1p