Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Dilan Khalili"'
Autor:
Dilan Khalili, Mubasher Mohammed, Martin Kunc, Martina Sindlerova, Johan Ankarklev, Ulrich Theopold
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTumor-associated macrophages may act to either limit or promote tumor growth, yet the molecular basis for either path is poorly characterized.MethodsWe use a larval Drosophila model that expresses a dominant-active version of the Ras-onco
Externí odkaz:
https://doaj.org/article/5eb3d955d25a44559ffd68543ba28b27
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionChitinase-like proteins (CLPs) are associated with tissue-remodeling and inflammation but also with several disorders, including fibrosis, atherosclerosis, allergies, and cancer. However, CLP’s role in tumors is far from clear. MethodsH
Externí odkaz:
https://doaj.org/article/52fc893ffaa1407981178991d5c60bff
Publikováno v:
Journal of Innate Immunity, Pp 1-15 (2021)
Fibrotic lesions accompany several pathological conditions, including tumors. We show that expression of a dominant-active form of the Ras oncogene in Drosophila salivary glands (SGs) leads to redistribution of components of the basement membrane (BM
Externí odkaz:
https://doaj.org/article/385755a0fac940dc9662b2af885f1165
Publikováno v:
eLife, Vol 9 (2020)
Postmitotic tissues are incapable of replacing damaged cells through proliferation, but need to rely on buffering mechanisms to prevent tissue disintegration. By constitutively activating the Ras/MAPK-pathway via RasV12-overexpression in the postmito
Externí odkaz:
https://doaj.org/article/9a2a7442136b4d7b82958437a96541b2
Autor:
Kassiani Skouloudaki, Ioannis Christodoulou, Dilan Khalili, Vasilios Tsarouhas, Christos Samakovlis, Pavel Tomancak, Elisabeth Knust, Dimitrios K. Papadopoulos
Publikováno v:
Journal of Cell Biology. 222
Publikováno v:
Journal of Innate Immunity. 13:376-390
Fibrotic lesions accompany several pathological conditions, including tumors. We show that expression of a dominant-active form of the Ras oncogene in Drosophila salivary glands (SGs) leads to redistribution of components of the basement membrane (BM
Autor:
Dimitrios K. Papadopoulos, Christos Samakovlis, Kassiani Skouloudaki, Pavel Tomancak, Elisabeth Knust, Dilan Khalili, Vasilios Tsarouhas, Ioannis Christodoulou
Publikováno v:
The Journal of Cell Biology
Skouloudaki, K, Christodoulou, I, Khalili, D, Tsarouhas, V, Samakovlis, C, Tomancak, P, Knust, E & Papadopoulos, D K 2019, ' Yorkie controls tube length and apical barrier integrity during airway development ', Journal of Cell Biology, vol. 218, no. 8, pp. 2762-2781 . https://doi.org/10.1083/jcb.201809121
Skouloudaki, K, Christodoulou, I, Khalili, D, Tsarouhas, V, Samakovlis, C, Tomancak, P, Knust, E & Papadopoulos, D K 2019, ' Yorkie controls tube length and apical barrier integrity during airway development ', Journal of Cell Biology, vol. 218, no. 8, pp. 2762-2781 . https://doi.org/10.1083/jcb.201809121
Skouloudaki et al. identify an alternative role of the transcriptional coactivator Yorkie (Yki) in controlling water impermeability and tube size of developing Drosophila airways. Tracheal impermeability is triggered by Yki-mediated transcriptional r
Publikováno v:
Journal of Innate Immunity, Pp 1-15 (2021)
J Innate Immun
J Innate Immun
Fibrotic lesions accompany several pathological conditions including tumors. We show that expression of a dominant-active form of the Ras oncogene in Drosophila salivary glands (SGs) leads to redistribution of components of the basement membrane (BM)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb1551f278c262bab766c442a5265cf
https://www.karger.com/Article/FullText/516104
https://www.karger.com/Article/FullText/516104
Postmitotic tissues are incapable of replacing damaged cells through proliferation, but need to rely on buffering mechanisms to prevent tissue disintegration. By constitutively activating the Ras/MAPK-pathway viaRasV12-overexpression in the postmitot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e718204c9b1b9a67a65fbeab47ffdf