Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Dike N. Kalu"'
Publikováno v:
Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine. 220:573-578
Previous studies have demonstrated that male Sprague Dawley (SD) rats experience age-related bone loss with the same characteristics as that in ageing men. As articular cartilage, like bone, is a critical component of the health and function of the m
Autor:
Dike N. Kalu, Jameela Banu
Publikováno v:
Bone. 34:432-442
It is well established that age-related bone loss occurs in men and male SD rats. This study was designed to determine whether cerivastatin will prevent age-related bone loss in male Sprague-Dawley (SD) rats. Parathyroid hormone (PTH) was used as a p
Publikováno v:
Calcified Tissue International. 73:196-201
It has been hypothesized that increase in muscle mass increases the strain on bone resulting in increase in bone mass. The aim of the present study was to determine the effects of increased muscle mass on bone. A colony of transgenic mice that overex
Publikováno v:
Aging Clinical and Experimental Research. 13:282-292
The focus of this study is on whether cortical osteopenia occurs in ovariectomized aged female rats, and if so, whether growth hormone (GH) and parathyroid hormone (PTH) independently or together (GH+PTH) can rebuild the lost cortical bone. Tibio-fib
Publikováno v:
Bone. 29:141-148
Osteoporosis is a common occurrence in aging men. There is currently no appropriate animal model for studying age-related bone loss in men. To determine whether male Sprague-Dawley (SD) rats experience bone loss with aging and whether this rodent mod
Publikováno v:
Mechanisms of Ageing and Development. 122:849-864
The aim of this study is to determine the effects of growth hormone (GH), exercise (EX), GH+EX and food restriction on cancellous bone in middle-aged female rats. Female F344 rats aged 13 months were divided into (1) age-matched controls; (2) GH trea
Publikováno v:
Mosekilde, L, Erikstrup, L T, Thomsen, J S, Orhii, P B, Banu, M J & Kalu, D N 2000, ' Parathyroid hormone and growth hormone have additive or synergetic effect when used as intervention treatment in ovariectomized rats with established osteopenia ', Bone, vol. 26, no. 6, pp. 643-51 . https://doi.org/10.1016/S8756-3282(00)00276-3
The severely osteoporotic human skeleton is characterized by thin cortices and a very fragile cancellous framework. To increase the biomechanical competence of such a skeleton, powerful anabolic agents are needed. The aim of the present study was to
Autor:
P. B. Orhii, Dike N. Kalu
Publikováno v:
Calcified Tissue International. 65:73-77
The following studies were undertaken to examine whether estrogen deficiency impairs calcium absorption in aged rats, and to determine whether impaired calcium absorption and the level of dietary calcium are related to the degree of bone loss due to
Publikováno v:
Journal of Bone and Mineral Research. 14:802-809
Peak volumetric bone mineral density (BMD) is determined by the growth in bone size relative to the mineral accrued within its periosteal envelope. Thus, reduced peak volumetric BMD may be the result of reduced mineral accrual relative to growth in b
Autor:
Cang Chen, Dike N. Kalu
Publikováno v:
Journal of Bone and Mineral Research. 14:593-601
Two experiments were carried out to examine whether the ovariectomized mouse is a potential in vivo model of intestinal calcium malabsorption as occurs in postmenopausal osteoporosis. In the first experiment, we compared the effects of ovariectomy an